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1.WO/2018/111326METHODS AND INGESTIBLE DEVICES FOR THE REGIO-SPECIFIC RELEASE OF IMMUNOSUPPRESSANTS AT THE SITE OF GASTROINTESTINAL TRACT DISEASE
WO 21.06.2018
国际分类 A61K 9/00
A人类生活必需
61医学或兽医学;卫生学
K医用、牙科用或梳妆用的制剂
9以特殊物理形状为特征的医药配制品
申请号 PCT/US2017/025116 申请人 PROGENITY INC. 发明人 JONES, Mitchell Lawrence
This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with an immunosuppressant.
2.WO/2018/111328METHODS AND INGESTIBLE DEVICES FOR THE REGIO-SPECIFIC RELEASE OF TNF INHIBITORS AT THE SITE OF GASTROINTESTINAL TRACT DISEASE
WO 21.06.2018
国际分类 A61M 31/00
A人类生活必需
61医学或兽医学;卫生学
M将介质输入人体内或输到人体上的器械;为转移人体介质或为从人体内取出介质的器械;用于产生或结束睡眠或昏迷的器械
31体腔中引入或保留介质,例如药物的器械
申请号 PCT/US2017/025119 申请人 PROGENITY INC. 发明人 JONES, Mitchell Lawrence
This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with a TNF inhibitor.
3.WO/2018/182612METHODS AND INGESTIBLE DEVICES FOR THE REGIO-SPECIFIC RELEASE OF STEM CELLS AT THE SITE OF GASTROINTESTINAL TRACT DISEASE
WO 04.10.2018
国际分类 A61K 35/545
A人类生活必需
61医学或兽医学;卫生学
K医用、牙科用或梳妆用的制剂
35含有其有不明结构的原材料或其反应产物的医用配制品
12来源于哺乳动物的材料的;包括非特定组织或细胞的组合物;包括非胚胎干细胞的组合物;基因重组细胞
48生殖器官
54卵巢;卵细胞;卵子;胚胎;胎细胞;胚细胞
545胚胎干细胞;多能干细胞;诱导性多能干细胞;未定性的干细胞
申请号 PCT/US2017/024997 申请人 PROGENITY INC. 发明人 JONES, Mitchell Lawrence
This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with a stem cell.
4.WO/2018/111321METHODS AND INGESTIBLE DEVICES FOR THE REGIO-SPECIFIC RELEASE OF IL-12/IL-23 INHIBITORS AT THE SITE OF GASTROINTESTINAL TRACT DISEASE
WO 21.06.2018
国际分类 A61K 9/00
A人类生活必需
61医学或兽医学;卫生学
K医用、牙科用或梳妆用的制剂
9以特殊物理形状为特征的医药配制品
申请号 PCT/US2017/025053 申请人 PROGENITY INC. 发明人 JONES, Mitchell Lawrence
This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with an IL-12/IL-23 inhibitor. An embodiment of the disclosure relates to releasing the IL-12/IL-13 inhibitor at a location in the gastrointestinal tract of a subject that is proximate to one or more sites of disease, by administering an orally ingestible delivery device comprising such IL-12/IL-23 inhibitor, said device comprise of an ingestible housing comprising a reservoir that contains the IL-12/IL-23 inhibitor, a detector coupled to the ingestible housing, a valve system in fluid communication with the reservoir, and a controller communicably coupled to the valve and the detector.
5.WO/2018/111329METHODS AND INGESTIBLE DEVICES FOR THE REGIO-SPECIFIC RELEASE OF IL-1 INHIBITORS AT THE SITE OF GASTROINTESTINAL TRACT DISEASE
WO 21.06.2018
国际分类 A61K 9/00
A人类生活必需
61医学或兽医学;卫生学
K医用、牙科用或梳妆用的制剂
9以特殊物理形状为特征的医药配制品
申请号 PCT/US2017/025143 申请人 PROGENITY INC. 发明人 JONES, Mitchell Lawrence
This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with an IL-1 inhibitor. An embodiment of the disclosure relates to releasing the IL- 1 inhibitor at a location in the gastrointestinal tract of a subject that is proximate to one or more sites of disease, by administering an orally ingestible delivery device comprising such IL-1 inhibitor, said device comprise of an ingestible housing comprising a reservoir that contains the IL-1 inhibitor, a detector coupled to the ingestible housing, a valve system in fluid communication with the reservoir, and a controller communicably coupled to the valve and the detector.
6.WO/2018/111322METHODS AND INGESTIBLE DEVICES FOR THE REGIO-SPECIFIC RELEASE OF INTEGRIN INHIBITORS AT THE SITE OF GASTROINTESTINAL TRACT DISEASE
WO 21.06.2018
国际分类 A61K 9/00
A人类生活必需
61医学或兽医学;卫生学
K医用、牙科用或梳妆用的制剂
9以特殊物理形状为特征的医药配制品
申请号 PCT/US2017/025059 申请人 PROGENITY INC. 发明人 JONES, Mitchell Lawrence
This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with an integrin inhibitor.
7.WO/2018/111323METHODS AND INGESTIBLE DEVICES FOR THE REGIO-SPECIFIC RELEASE OF SMAD7 INHIBITORS AT THE SITE OF GASTROINTESTINAL TRACT DISEASE
WO 21.06.2018
国际分类 A61K 9/00
A人类生活必需
61医学或兽医学;卫生学
K医用、牙科用或梳妆用的制剂
9以特殊物理形状为特征的医药配制品
申请号 PCT/US2017/025082 申请人 PROGENITY INC. 发明人 JONES, Mitchell Lawrence
This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with a SMAD7 inhibitor.
8.WO/2018/111327METHODS AND INGESTIBLE DEVICES FOR THE REGIO-SPECIFIC RELEASE OF JAK INHIBITORS AT THE SITE OF GASTROINTESTINAL TRACT DISEASE
WO 21.06.2018
国际分类 A61K 9/00
A人类生活必需
61医学或兽医学;卫生学
K医用、牙科用或梳妆用的制剂
9以特殊物理形状为特征的医药配制品
申请号 PCT/US2017/025117 申请人 PROGENITY INC. 发明人 JONES, Mitchell Lawrence
This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with a JAK inhibitor.
9.WO/2018/182641METHODS AND INGESTIBLE DEVICES FOR THE REGIO-SPECIFIC RELEASE OF IL-13 INHIBITORS AT THE SITE OF GASTROINTESTINAL TRACT DISEASE
WO 04.10.2018
国际分类 A61K 9/00
A人类生活必需
61医学或兽医学;卫生学
K医用、牙科用或梳妆用的制剂
9以特殊物理形状为特征的医药配制品
申请号 PCT/US2017/025142 申请人 PROGENITY INC. 发明人 JONES, Mitchell Lawrence
This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with an IL-13 inhibitor. An embodiment of the disclosure relates to releasing the IL- 13 inhibitor at a location in the gastrointestinal tract of a subject that is proximate to one or more sites of disease, by administering an orally ingestible delivery device comprising such IL-13 inhibitor, said device comprise of an ingestible housing comprising a reservoir that contains the IL- 13 inhibitor, a detector coupled to the ingestible housing, a valve system in fluid communication with the reservoir, and a controller communicably coupled to the valve and the detector.
10.WO/2018/111325METHODS AND INGESTIBLE DEVICES FOR THE REGIO-SPECIFIC RELEASE OF IL-6R INHIBITORS AT THE SITE OF GASTROINTESTINAL TRACT DISEASE
WO 21.06.2018
国际分类 A61K 39/395
A人类生活必需
61医学或兽医学;卫生学
K医用、牙科用或梳妆用的制剂
39含有抗原或抗体的医药配制品
395抗体;免疫球蛋白;免疫血清,例如抗淋巴细胞血清
申请号 PCT/US2017/025102 申请人 PROGENITY INC. 发明人 JONES, Mitchell Lawrence
This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with an IL-6R inhibitor.