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PUBLICATION_DATE=2009
1 / 1
1.WO/2009/1341105-ARYL-4-(5-SUBSTITUTED 2,4-DIHYDROXYPHENYL)-1,2,3-THIADIAZOLES AS INHIBITORS OF HSP90 CHAPERONE AND THE INTERMEDIATES FOR PRODUCTION THEREOF
WO - 05.11.2009
国际分类 C07D 285/06
C化学;冶金
07有机化学
D杂环化合物(高分子化合物入C08)
285杂环化合物,有氮原子和硫原子作为仅有的杂环原子的环,不包含在C07D275/00至C07D283/00组中
01五元环
02噻二唑;氢化噻二唑
04不和其他环稠合
061,2,3-Thiadiazoles; Hydrogenated 1,2,3-thiadiazoles
 申请号 PCT/LT2008/000003 申请人 BIOTECHNOLOGIJOS INSTITUTAS 发明人 MATULIS, Daumantas
Invention is related to novel compounds - 5-aryl-4-(5-substituted 2,4-dihydroxyphenyl)-1,2,3-thiadiazoles with general formula (I). The compounds can be used in biomedicine as active ingredients in pharmaceutical formulations, because they inhibit Hsp90 chaperone which participate in cancer progression. This invention is also related to new intermediate compounds which are used for the synthesis of thiadiazoles of general formula (I).
2.2054420BENZIMIDAZO[1,2-C][1,2,3]THIADIAZOL-7-SULFONSÄUREAMIDE ALS CARBOANHYDRASEINHIBITOREN UND ZWISCHENPRODUKTE ZU DEREN HERSTELLUNG
EP - 06.05.2009
国际分类 C07D 513/04
C化学;冶金
07有机化学
D杂环化合物(高分子化合物入C08)
513杂环化合物,在稠环系中至少有1个杂环具有氮原子和硫原子作为仅有的杂环原子,不包含在C07D463/00、C07D477/00或C07D499/00至C07D507/00组中
02稠环系中含有两个杂环
04邻位稠合系
 申请号 07793796 申请人 BIOTECHNOLOGIJOS INST 发明人 MATULIS DAUMANTAS
The invention is related to novel compounds - benzimidazo[1,2-c][1,2,3]thiadiazole sulfonamides, corresponding to the general formula (I). The compounds can be used in biomedicine as active ingredients in pharmaceutical formulations, because they inhibit enzymes which participate in disease progression such as glaucome. The compounds of formula (I) inhibits enzymes such as carbonic anhydrases and metallo proteinases. This invention is also related to new intermediate compounds which are used for the synthesis of sulfonamides of formula (I).
3.2054420BENZIMIDAZO[1,2-C][1,2,3]THIADIAZOL-7-SULFONSÄUREAMIDE ALS CARBOANHYDRASEINHIBITOREN UND ZWISCHENPRODUKTE ZU DEREN HERSTELLUNG
EP - 06.05.2009
国际分类 C07D 513/04
C化学;冶金
07有机化学
D杂环化合物(高分子化合物入C08)
513杂环化合物,在稠环系中至少有1个杂环具有氮原子和硫原子作为仅有的杂环原子,不包含在C07D463/00、C07D477/00或C07D499/00至C07D507/00组中
02稠环系中含有两个杂环
04邻位稠合系
 申请号 07793796 申请人 BIOTECHNOLOGIJOS INST 发明人 MATULIS DAUMANTAS
The invention is related to novel compounds - benzimidazo[1,2-c][1,2,3]thiadiazole sulfonamides, corresponding to the general formula (I). The compounds can be used in biomedicine as active ingredients in pharmaceutical formulations, because they inhibit enzymes which participate in disease progression such as glaucome. The compounds of formula (I) inhibits enzymes such as carbonic anhydrases and metallo proteinases. This invention is also related to new intermediate compounds which are used for the synthesis of sulfonamides of formula (I).
4.56235-ARYL-4-(5-SUBSTITUTED 2,4-DIHYDROXYFENIL)-1,2,3-THIADIAZOLES AS INHIBITORS OF HSP90 CHAPERONE AND THE INTERMEDIATES FOR PRODUCTION THEREOF
LT - 25.11.2009
国际分类 C07D 285/00
C化学;冶金
07有机化学
D杂环化合物(高分子化合物入C08)
285杂环化合物,有氮原子和硫原子作为仅有的杂环原子的环,不包含在C07D275/00至C07D283/00组中
 申请号 2008035 申请人 BIOTECHNOLOGIJOS INST 发明人 MATULIS DAUMANTAS
Ivention is related to novel compounds - 5-aryl-4-(5-substituted 2,4-dihydroxyphenyl)-1,2,3-thiadiazoles with general formula (I). The compounds can be used in biomedicine as active ingredients in pharmaceutical formulations, because they inhibit Hsp90 chaperone which participate in cancer progression. This invention is also related to new intermediate compounds which are used for the synthesis of thiadiazoles of formula (I).@
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