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IC:G01N33/569 AND EN_ALLTXT:(coronavirus OR coronaviruses OR coronaviridae OR coronavirinae OR orthocoronavirus OR orthocoronaviruses OR orthocoronaviridae OR orthocoronavirinae OR betacoronavirus OR betacoronaviruses OR betacoronaviridae OR betacoronavirinae OR sarbecovirus OR sarbecoviruses OR sarbecoviridae OR sarbecovirinae OR "severe acute respiratory syndrome" OR sars OR "2019 ncov" OR covid)

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1 / 346
1.WO/2023/102512PREDICTION OF SEVERITY OF COVID-19 AND METHODS OF TREATMENT
WO - 08.06.2023
国际分类 G01N 33/569
G物理
01用于测量的传感器,如敏感元件
N借助于测定材料的化学或物理性质来测试或分析材料
33利用不包括在G01N1/00至G01N31/00组中的特殊方法来研究或分析材料
48生物物质,例如血、尿;血球计数器
50生物物质(例如血、尿)的化学分析;包括了生物特有的配体结合方法的测试;免疫学试验
53免疫测定法;生物特异性结合测定;相应的生物物质
569用于微生物,例如原生动物、细菌、病毒
 申请号 PCT/US2022/080795 申请人 VANDA PHARMACEUTICALS INC. 发明人 SMIESZEK, Sandra
The invention relates generally to coronavirus disease 2019 (COVID-19) and more particularly to the prediction of severity of COVID-19 manifestation in a patient or in an individual at risk of infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) based on a level of chemokine (C-X-C motif) ligand 16 (CXCL16) expression in and/or the rs10490770 genotype of the patient or individual.
2.WO/2021/204770PRO-ADRENOMEDULLIN FOR PROGNOSING DISEASE PROGRESSION IN SEVERE ACUTE RESPIRATORY SYNDROME (SARS)
WO - 14.10.2021
国际分类 G01N 33/569
G物理
01用于测量的传感器,如敏感元件
N借助于测定材料的化学或物理性质来测试或分析材料
33利用不包括在G01N1/00至G01N31/00组中的特殊方法来研究或分析材料
48生物物质,例如血、尿;血球计数器
50生物物质(例如血、尿)的化学分析;包括了生物特有的配体结合方法的测试;免疫学试验
53免疫测定法;生物特异性结合测定;相应的生物物质
569用于微生物,例如原生动物、细菌、病毒
 申请号 PCT/EP2021/058885 申请人 B.R.A.H.M.S GMBH 发明人 EBMEYER, Stefan
The invention relates to a method for prognosing disease progression in a patient that has or is at risk of developing a severe acute respiratory syndrome (SARS), wherein the method comprises determining a level of pro-adrenomedullin (proADM) or fragment(s) thereof in a sample from the patient, wherein said level indicates the severity of SARS progression. The method is in some embodiments configured for use when a patient exhibits symptoms of a severe acute respiratory syndrome (SARS), a patient exhibits symptoms of infection with a SARS-virus, the patient is infected with a SARS-virus, such as a SARS-coronavirus, such as SARS-CoV2.
3.WO/2022/015573SARS-COV-2 ANTIGEN-BINDING PROTEINS AND USES THEREOF
WO - 20.01.2022
国际分类 A61K 39/42
A人类生活必需
61医学或兽医学;卫生学
K医用、牙科用或梳妆用的制剂
39含有抗原或抗体的医药配制品
395抗体;免疫球蛋白;免疫血清,例如抗淋巴细胞血清
42病毒性的
 申请号 PCT/US2021/040900 申请人 PRESIDENT AND FELLOWS OF HARVARD COLLEGE 发明人 ABRAHAM, Jonathan
The present invention provides severe acute respiratory syndrome coronavirus (SARS-CoV), e.g., severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigen-binding proteins and methods of use thereof to passively immunize and treat subjects having or at risk of having a SARS-CoV, e.g., SARS-CoV-2, infection.
4.20210373020Systems and processes to screen for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) of 2019 (COVID-19)
US - 02.12.2021
国际分类 G01N 33/569
G物理
01用于测量的传感器,如敏感元件
N借助于测定材料的化学或物理性质来测试或分析材料
33利用不包括在G01N1/00至G01N31/00组中的特殊方法来研究或分析材料
48生物物质,例如血、尿;血球计数器
50生物物质(例如血、尿)的化学分析;包括了生物特有的配体结合方法的测试;免疫学试验
53免疫测定法;生物特异性结合测定;相应的生物物质
569用于微生物,例如原生动物、细菌、病毒
 申请号 17337022 申请人 BATTELLE MEMORIAL INSTITUTE 发明人 Melicia R. Gainey

Alternative antibodies to screen for SARS-CoV-2 are disclosed. One alternative antibody is Mouse Species Coronavirus (COVID-19, MERS, and SARS-CoV NP) Antibody, Catalog Number HM1056 (“E3-Antibody” or “E3”), from EastCoast Bio, Inc., PO Box 489, North Berwick, ME 03906, USA (“EastCoast Bio”). Another alternative antibody is a combination of the E3-Antibody and Mouse Species Coronavirus (COVID-19, MERS, and SARS-CoV NP) Antibody, Catalog Number HM1057 (“E1-Antibody” or “E1”), from EastCoast Bio (the combination of the E1-Antibody and the E3-Antibody is designated as “E1/E3-Antibody” or simply “E1/E3”). Yet another alternative antibody is a combination of Mouse Species Anti-SARS-CoV-2 NP mAb, clone 4B21, Catalog Number CABT-CS027 (“C4-Antibody” or “C4”), from Creative Diagnostics, 45-1 Ramsey Road, Shirley, NY 11967, USA (“Creative Diagnostics”), and Mouse Species Anti-SARS-CoV-2 NP mAb, clone 7G21, Catalog Number CABT-CS026 (“C5-Antibody” or “C5”), also from Creative Diagnostics (the combination of the C4-Antibody and the C5-Antibody is designated as “C4/C5-Antibody” or simply “C4/C5”).

5.WO/2021/207962ANTIBODIES TO SARS-CORONAVIRUS (COVID-19) S1 SPIKE PROTEIN
WO - 21.10.2021
国际分类 C07K 16/10
C化学;冶金
07有机化学
K肽
16免疫球蛋白,例如,单克隆或多克隆抗体
08抗来自病毒的物质
10来自RNA病毒
 申请号 PCT/CN2020/084857 申请人 ACTIVE MOTIF SHANGHAI LIMITED 发明人 LU, Yanan
Provided are recombinant monoclonal antibodies that bind to the Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2 or COVID-19) spike protein and using methods thereof. The antibodies can inhibit or neutralize SARS-CoV-2 activity, thus can be used for treating or preventing or diagnosing COVID-19 infection in humans.
6.20230324402DEVICES FOR DETECTING ANTIBODIES TO CORONAVIRUS ANTIGENS AND METHODS FOR USING THEM
US - 12.10.2023
国际分类 G01N 33/68
G物理
01用于测量的传感器,如敏感元件
N借助于测定材料的化学或物理性质来测试或分析材料
33利用不包括在G01N1/00至G01N31/00组中的特殊方法来研究或分析材料
48生物物质,例如血、尿;血球计数器
50生物物质(例如血、尿)的化学分析;包括了生物特有的配体结合方法的测试;免疫学试验
68涉及蛋白质、肽或氨基酸的
 申请号 17914149 申请人 The Regents of the University of California 发明人 Phillip L. FELGNER

In alternative embodiments, provided are multiplexed systems, compositions, including products of manufacture such as arrays, microarrays and biochips, and kits, and methods, for detecting presence of a coronavirus in a sample, or to detect a coronavirus, e.g., COVID-19, infection. In alternative embodiments, provided are methods for detecting the presence of a coronavirus infection in an individual. In alternative embodiments, provided are vaccines and methods for using them to prevent, mitigate or lessen to effects of, or treat a coronavirus infection in an individual.

7.WO/2022/011160SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS COV-2) PEPTIDE EPITOPES
WO - 13.01.2022
国际分类 G01N 33/569
G物理
01用于测量的传感器,如敏感元件
N借助于测定材料的化学或物理性质来测试或分析材料
33利用不包括在G01N1/00至G01N31/00组中的特殊方法来研究或分析材料
48生物物质,例如血、尿;血球计数器
50生物物质(例如血、尿)的化学分析;包括了生物特有的配体结合方法的测试;免疫学试验
53免疫测定法;生物特异性结合测定;相应的生物物质
569用于微生物,例如原生动物、细菌、病毒
 申请号 PCT/US2021/040920 申请人 THE BRIGHAM AND WOMEN'S HOSPITAL, INC. 发明人 ELLEDGE, Stephen J.
Peptide epitopes identified in subjects infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and methods of use thereof for diagnosing, determining prognosis, and treating Coronavirus Disease 2019 (COVID-19), and developing prophylactic or therapeutic vaccines against SARS-CoV-2.
8.10948490Severe acute respiratory syndrome (SARS)—associated coronavirus diagnostics
US - 16.03.2021
国际分类 G01N 33/569
G物理
01用于测量的传感器,如敏感元件
N借助于测定材料的化学或物理性质来测试或分析材料
33利用不包括在G01N1/00至G01N31/00组中的特殊方法来研究或分析材料
48生物物质,例如血、尿;血球计数器
50生物物质(例如血、尿)的化学分析;包括了生物特有的配体结合方法的测试;免疫学试验
53免疫测定法;生物特异性结合测定;相应的生物物质
569用于微生物,例如原生动物、细菌、病毒
 申请号 16944649 申请人 INSTITUT PASTEUR 发明人 Sylvie Van Der Werf

The invention relates to the diagnosis of a SARS-associated coronavirus, such as a SARS CoV-2 infection and SARS-CoV infection, using the SARS-CoV and SARS-CoV-2 nucleocapsid proteins and antibodies binding to these proteins. The invention encompasses reagents, methods and kits for the detection of a SARS-associated coronavirus.

9.20150275183Human Betacoronavirus lineage C and identification of N-terminal dipeptidyl peptidase as its virus receptor
US - 01.10.2015
国际分类 C12N 7/00
C化学;冶金
12生物化学;啤酒;烈性酒;果汁酒;醋;微生物学;酶学;突变或遗传工程
N微生物或酶;其组合物;繁殖、保藏或维持微生物;变异或遗传工程;培养基。
7病毒,如噬菌体;其组合物;其制备或纯化
 申请号 14430010 申请人 Erasmus University Medical Center Rotterdam 发明人 Bartholomeus Leonardus Haagmans

The invention provides an isolated essentially mammalian positive-sense single stranded RNA virus classifiable as belonging to the Order: Nidovirales; Family: Coronaviridae; Subfamily: Coronavirinae; Genus: Betacoronavirus; and non-Lineage A, non-Lineage B or non-Lineage D, human betacoronavirus. The invention also provides a human virus having a receptor binding domain (RBD) capable of binding to a dipeptidyl peptidase 4. The invention also provides diagnostic means and methods, prophylactic means and methods and therapeutic means and methods to be employed in the diagnosis, prevention and/or treatment of disease, in particular of respiratory disease, in particular of mammals, more in particular in humans.

10.WO/2021/247631SYSTEMS AND PROCESSES TO SCREEN FOR SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-COV-2) OF 2019 (COVID-19)
WO - 09.12.2021
国际分类 G01N 33/569
G物理
01用于测量的传感器,如敏感元件
N借助于测定材料的化学或物理性质来测试或分析材料
33利用不包括在G01N1/00至G01N31/00组中的特殊方法来研究或分析材料
48生物物质,例如血、尿;血球计数器
50生物物质(例如血、尿)的化学分析;包括了生物特有的配体结合方法的测试;免疫学试验
53免疫测定法;生物特异性结合测定;相应的生物物质
569用于微生物,例如原生动物、细菌、病毒
 申请号 PCT/US2021/035335 申请人 BATTELLE MEMORIAL INSTITUTE 发明人 GAINEY, Melicia, R.
Systems and processes to screen for SARS-CoV-2, which includes a process that uses an alternative antibody for ELISA. The alternative antibody is an alternative to a mouse antibody, thereby expanding the ability to test for COVID-19 using non-human antibodies.
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