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IC:C12M3/00 AND EN_ALLTXT:(coronavirus OR coronaviruses OR coronaviridae OR coronavirinae OR orthocoronavirus OR orthocoronaviruses OR orthocoronaviridae OR orthocoronavirinae OR betacoronavirus OR betacoronaviruses OR betacoronaviridae OR betacoronavirinae OR sarbecovirus OR sarbecoviruses OR sarbecoviridae OR sarbecovirinae OR "severe acute respiratory syndrome" OR sars OR "2019 ncov" OR covid)

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1 / 16
1.20070042350Methods and compositions for detecting sars virus and other infectious agents
US - 22.02.2007
国际分类 C12Q 1/70
C化学;冶金
12生物化学;啤酒;烈性酒;果汁酒;醋;微生物学;酶学;突变或遗传工程
Q包含酶、核酸或微生物的测定或检验方法;其所用的组合物或试纸;这种组合物的制备方法;在微生物学方法或酶学方法中的条件反应控制
1包含酶、核酸或微生物的测定或检验方法;其组合物;这种组合物的制备方法
70包括病毒或噬菌体
 申请号 10564378 申请人 LI ZE 发明人 Li Ze

This invention relates generally to the field of virus detection. In particular, the invention provides chips, probes, primers, kits and methods for amplifying and detecting SARS-CoV nucleotides sequence. The clinical and other uses of the present chips, probes, primers, kits and methods are also contemplated.

2.WO/2021/202066METHOD AND SYSTEM FOR PROCESSING GENETIC DATA
WO - 07.10.2021
国际分类 C12M 1/34
C化学;冶金
12生物化学;啤酒;烈性酒;果汁酒;醋;微生物学;酶学;突变或遗传工程
M酶学或微生物学装置
1酶学或微生物学装置
34用条件测量或信号传感方法测量或检验,如菌落计数器
 申请号 PCT/US2021/021551 申请人 ALIBABA GROUP HOLDING LIMITED 发明人 GU, Fei
Processing genetic data is disclosed including inputting data, the data corresponding to source data for gene sequencing on a sample, receiving a selected data processing technique, performing, using the selected data processing technique, gene sequencing processing on the inputted data based on the pathogen genome of a predetermined pathogen to obtain a data processing result, the data processing result indicating whether the sample includes the predetermined pathogen, and presenting the data processing result.
3.20230174946ORGAN INFECTION MODELS
US - 08.06.2023
国际分类 C12N 5/071
C化学;冶金
12生物化学;啤酒;烈性酒;果汁酒;醋;微生物学;酶学;突变或遗传工程
N微生物或酶;其组合物;繁殖、保藏或维持微生物;变异或遗传工程;培养基。
5未分化的人类、动物或植物细胞,如细胞系;组织;它们的培养或维持;其培养基
07动物细胞或组织
071脊椎动物细胞或组织,例如人类细胞或组织
 申请号 17922162 申请人 CEDARS-SINAI MEDICAL CENTER 发明人 Barry R. Stripp

Described herein are particular infection model systems, methods of studying infection, and method of screening compounds in various model systems. Particularly, SARS-CoV-2 is studied in these organ and infection models.

4.WO/2022/081568DETECTION OF ACE2 IgM AUTOANTIBODIES AS MARKERS OF SEVERITY AND MECHANISM IN COVID19 PATIENTS
WO - 21.04.2022
国际分类 G01N 33/53
G物理
01用于测量的传感器,如敏感元件
N借助于测定材料的化学或物理性质来测试或分析材料
33利用不包括在G01N1/00至G01N31/00组中的特殊方法来研究或分析材料
48生物物质,例如血、尿;血球计数器
50生物物质(例如血、尿)的化学分析;包括了生物特有的配体结合方法的测试;免疫学试验
53免疫测定法;生物特异性结合测定;相应的生物物质
 申请号 PCT/US2021/054571 申请人 THE JOHNS HOPKINS UNIVERSITY 发明人 ROSEN, Antony
Provided herein are methods for diagnosing the probability of extended duration of severe COVID19 symptoms in a subject infected with a SARS-CoV2 virus or suspected of being infected with the SARS-CoV2 virus, the method including (a) providing a biological sample from the subject; and (b) detecting the presence of an anti-ACE2 IgM antibody in the biological sample, thereby diagnosing the probability of extended duration of severe COVID19 symptoms in the subject.
5.20210341467PORTABLE DEVICES AND METHODS FOR DETECTING AND IDENTIFYING COMPOUNDS IN SALIVA
US - 04.11.2021
国际分类 G01N 33/543
G物理
01用于测量的传感器,如敏感元件
N借助于测定材料的化学或物理性质来测试或分析材料
33利用不包括在G01N1/00至G01N31/00组中的特殊方法来研究或分析材料
48生物物质,例如血、尿;血球计数器
50生物物质(例如血、尿)的化学分析;包括了生物特有的配体结合方法的测试;免疫学试验
53免疫测定法;生物特异性结合测定;相应的生物物质
543用不溶解的载体固定免疫化学物品
 申请号 16933525 申请人 Pelican Diagnostics Inc. 发明人 Raj Reddy

This disclosure relates to portable devices for SARS-COV-2 Antigen (SC2A), a biomarker for the detection of Coronavirus disease 2019 (COVID19). Diagnosis of viral infections such as SARS-COV-2 can be obtained in the early stages of a disease by detection of viral antigens (e.g., SC2A) directly in the clinical specimen.

6.WO/2022/107006METHODS AND DEVICES FOR RAPID DETECTION OF COVID-19 AND OTHER PATHOGENS
WO - 27.05.2022
国际分类 C12Q 1/6844
C化学;冶金
12生物化学;啤酒;烈性酒;果汁酒;醋;微生物学;酶学;突变或遗传工程
Q包含酶、核酸或微生物的测定或检验方法;其所用的组合物或试纸;这种组合物的制备方法;在微生物学方法或酶学方法中的条件反应控制
1包含酶、核酸或微生物的测定或检验方法;其组合物;这种组合物的制备方法
68包括核酸
6844核酸扩增反应
 申请号 PCT/IB2021/060631 申请人 KHALIFA UNIVERSITY OF SCIENCE AND TECHNOLOGY 发明人 ALAZZAM, Anas
A device (10) and method for detecting COVID-19 and other pathogens includes a sample compartment (26) contained within an interior of the device and having multiple apertures (32) for releasably receiving one or more test tubes (42) containing a biological sample. A bottom portion (48) of the test tube (42) is contained within the interior (22) of the device (10) and a top portion (46) of the test tube (42) is exposed to atmosphere. The biological sample is lysed using the device (10); the lysed sample is mixed with one or more primers and then amplification (RT-LAMP) is performed using the device (10). A thermally conductive material on or in proximity to the sample compartment (26) can facilitate precise heating of the compartment (26) and sample. A thermally insulative material can be inside the interior of the compartment housing (30). Multiple samples can be tested simultaneously. The results can be interpreted by a color change of the sample. The device (10) is efficient, portable, reliable, and re-usable.
7.WO/2021/195544NOVEL ANUCLEATED CELLS FOR THE TREATMENT OF DISEASES
WO - 30.09.2021
国际分类 A61K 35/12
A人类生活必需
61医学或兽医学;卫生学
K医用、牙科用或梳妆用的制剂
35含有其有不明结构的原材料或其反应产物的医用配制品
12来源于哺乳动物的材料的;包括非特定组织或细胞的组合物;包括非胚胎干细胞的组合物;基因重组细胞
 申请号 PCT/US2021/024442 申请人 PLATELET BIOGENESIS, INC. 发明人 HETT, Sunita R.
The present disclosure takes advantage of non-naturally existing, novel, anucleated platelets or platelet-like cells or platelet variants (collectively referred to as PECs) or derivatives thereof (i.e., genetically engineered), which share at least one common receptor, ligand or an antigen with endogenous cells that are targets for autoantibodies and effectuate their clearance. The present disclosure also takes advantage of viral adhesion or entry receptors or genetically engineered PECs or derivatives thereof, which are engineered to express viral adhesion or entry receptors, that specifically binds to viral proteins on viruses or viral particles and effectuate their clearance.
8.WO/2022/047154POINT OF CARE AND IMPROVED DETECTION AND QUANTIFICATION OF BIOMOLECULES
WO - 03.03.2022
国际分类 B01L 3/00
B作业;运输
01大类中的化学工艺及装置;
L化学或物理实验设备
3实验室用的容器或器皿,如实验室玻璃仪器;点滴器
 申请号 PCT/US2021/047948 申请人 CHAN ZUCKERBERG BIOHUB, INC. 发明人 ABATE, Adam
The present disclosure provides materials and methods for detecting the presence of a target, such as a nucleic acid, biomolecule or biological particle, or virus genome in a sample. The present disclosure further provides point of care detection methods that can be done quickly and simply, optionally without sophisticated instrumentation. The present disclosure further provides improved methods for detecting and quantifying detection signals from various emulsions.
9.20070092871Microarray for pathogen identification
US - 26.04.2007
国际分类 C12Q 1/70
C化学;冶金
12生物化学;啤酒;烈性酒;果汁酒;醋;微生物学;酶学;突变或遗传工程
Q包含酶、核酸或微生物的测定或检验方法;其所用的组合物或试纸;这种组合物的制备方法;在微生物学方法或酶学方法中的条件反应控制
1包含酶、核酸或微生物的测定或检验方法;其组合物;这种组合物的制备方法
70包括病毒或噬菌体
 申请号 11584379 申请人 CombiMatrix Corporation 发明人 Lodes Michael J.

There is disclosed a microarray device for pathogen identification and for subtyping influenza A. Pools of primers are disclosed and used to amplify any subtype of influenza A. Pathogen identification includes influenza A, influenza B, parainfluenza virus, adenovirus, enterovirus, rhinovirus, human metapneumovirus, respiratory syncytal virus, herpes simplex viruses, SARS coronavirus, Epstein-Barr virus, human herpes virus, pan bacteria, Chlamydia, Mycoplasma, streptococcus, Bacillus anthracis, Streptococcuspyogenes, Mycoplasmapneumoniae, Chlamydiapneumoniae, Bacillus thuringiensis, Bacillus subtilis, Bacillus cereus, and B. anthracis. The probes are preferably selected from the first 500 nt of a gene from the 5′ end. The primers are preferably selected from bases in the 500 to 600 nt range from the 5′ end.

10.WO/2023/141532DETECTION OF CONDENSED AMPLIFICATION PRODUCTS
WO - 27.07.2023
国际分类 C12Q 1/68
C化学;冶金
12生物化学;啤酒;烈性酒;果汁酒;醋;微生物学;酶学;突变或遗传工程
Q包含酶、核酸或微生物的测定或检验方法;其所用的组合物或试纸;这种组合物的制备方法;在微生物学方法或酶学方法中的条件反应控制
1包含酶、核酸或微生物的测定或检验方法;其组合物;这种组合物的制备方法
68包括核酸
 申请号 PCT/US2023/060940 申请人 THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 发明人 PELECHANO GARCIA, Vicente Jose
Provided herein is a method for detecting a target nucleic acid in a sample. In some embodiments, the method may comprise: (a) amplifying the target nucleic acid isothermally in the presence of one or more compaction oligonucleotides to produce a product that comprises condensed amplification products; (b) flowing the product through a microfluidic channel; and (c) detecting a change in impedance as the condensed amplification products pass through the microfluidic channel. A microfluidic system and kit for preforming the method are also provided.
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