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1. WO2020182927 - AGENTS DE LIAISON AU POTASSIUM DESTINÉS À ÊTRE UTILISÉS CHEZ DES PATIENTS SOUS HÉMODIALYSE


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INTERNATIONAL SEARCH REPORT (ISR)
Part 1:  1  2  3  4  5  6          Part 2:  A  B  C  D  E 
International application No. Applicant's or agent's file reference
PCT/EP2020/056595 200823-WO-PCT
International filing date (day/month/year) (Earliest) Priority Date (day/month/year)
12 March 2020 13 March 2019
Applicant
ASTRAZENECA AB
FOR FURTHER ACTION: See Form PCT/ISA/220 as well as, where applicable, item 5 below.
This international search report has been prepared by this International Searching Authority and is transmitted to the applicant according to Article 18. A copy is being transmitted to the International Bureau.
It is also accompanied by a copy of each prior art document cited in this report.
1. Basis of the report
a. With regard to the language, the international search was carried out on the basis of:
the international application in the language in which it was filed.
a translation of the international application into                                          which is the language of a translation furnished for the purposes of international search (Rules 12.3(a) and 23.1(b)).
b.
This international search report has been established taking into account the rectification of an obvious mistake authorized by or notified to this Authority under Rule 91 (Rule 43.6bis(a)).
c.
With regard to any nucleotide and/or amino acid sequence disclosed in the international application, the international search was carried out on the basis of a sequence listing:
2. Certain claims were found unsearchable
3. Unity of invention is lacking
4. Title of the invention
The text is approved as submitted by the applicant.
The text has been established by this Authority to read as follows:
5. Abstract
The text is approved as submitted by the applicant.
The text has been established, according to Rule 38.2, by this Authority as it appears in Box No. IV. The applicant may, within one month from the date of mailing of this international search report, submit comments to this Authority.
6. Drawings
a.
The figure of the drawings to be published with the abstract is Figure No.     1    
as suggested by the applicant.
as selected by this Authority, because the applicant failed to suggest a figure.
as selected by this Authority, because this figure better characterizes the invention.
b.
none of the figures is to be published with the abstract.

A. CLASSIFICATION OF SUBJECT MATTER

     A61K 33/24 (2019.01)i; A61K 31/78 (2006.01)i; A61P 3/12 (2006.01)i
According to International Patent Classification (IPC) or to both national classification and IPC

B. FIELDS SEARCHED

Minimum documentation searched (classification system followed by classification symbols):
     A61K; A61P
Documentation searched other than minimum documentation to the extent that such documents are included in the fields searched:
Electronic data base consulted during the international search (name of data base and, where practicable, search terms used):
EPO-Internal, WPI Data, BIOSIS, EMBASE, CHEM ABS Data

C. DOCUMENTS CONSIDERED TO BE RELEVANT

Category* Citation of document, with indication, where appropriate, of the relevant passages Relevant to claim No.
(1)
X
CSABA P. KOVESDY ET AL, "Real-World Evaluation of Patiromer for the Treatment of Hyperkalemia in Hemodialysis Patients", KIDNEY INTERNATIONAL REPORTS,Vol. 4, No. 2, 01 February 2019 (2019-02-01), page 301-309,
XP055699854
1,4,8-10
the whole document
(2)
X
DAVID A. BUSHINSKY ET AL, "Patiromer Decreases Serum Potassium and Phosphate Levels in Patients on Hemodialysis", AMERICAN JOURNAL OF NEPHROLOGY,Vol. 44, No. 5, 01 January 2016 (2016-01-01), page 404-410,
XP055699859
1,4,8-10
the whole document
(3)
X
WO 2010022383 A2 (RELYPSA INC [US]; MANSKY PAUL [US] ET AL.) 25 February 2010 (2010-02-25)
1,4,8
paragraphs [0001], [0044]; claims 1-61,64,64
(4)
X
Anonymous, "NCT03303521 : A Phase 3b, Multicenter, Prospective, Randomized, Double Blind, Placebocontrolled Study to Reduce Incidence of Hyperkalemia With Sodium Zirconium Cyclosilicate (DIALIZE)", 17 September 2018 (2018-09-17),
Retrieved from the Internet:
URL:https://clinicaltrials.gov/ct2/history/NCT03303521?V_14=View#StudyPageTop
XP055699843
[retrieved on  2020-05-29]
1-8
the whole document
(5)
A
CALVIN J. MEANEY ET AL, "Systematic Review and Meta-Analysis of Patiromer and Sodium Zirconium Cyclosilicate: A New Armamentarium for the Treatment of Hyperkalemia", PHARMACOTHERAPY,Vol. 37, No. 4, 10 March 2017 (2017-03-10), page 401-411,
XP055699850
1-10
the whole document
(6)
A
DAVID K. PACKHAM ET AL, "Sodium Zirconium Cyclosilicate in Hyperkalemia", NEW ENGLAND JOURNAL OF MEDICINE,Vol. 372, No. 3, 21 November 2014 (2014-11-21), page 222-231,
XP055413209
1-8
the whole document
(7)
X,P
STEVEN FISHBANE ET AL, "A Phase 3b, Randomized, Double-Blind, Placebo-Controlled Study of Sodium Zirconium Cyclosilicate for Reducing the Incidence of Predialysis Hyperkalemia", JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY.,Vol. 30, No. 9, 14 June 2019 (2019-06-14), page 1723-1733,
XP055699844
1-8
the whole document
*
Special categories of cited documents:
"A"
document defining the general state of the art which is not considered to be of particular relevance
"D"
document cited by the applicant in the international application
"E"
earlier application or patent but published on or after the international filing date
"L"
document which may throw doubts on priority claim(s) or which is cited to establish the publication date of another citation or other special reason (as specified)
"O"
document referring to an oral disclosure, use, exhibition or other means
"P"
document published prior to the international filing date but later than the priority date claimed
"T"
later document published after the international filing date or priority date and not in conflict with the application but cited to understand the principle or theory underlying the invention
"X"
document of particular relevance; the claimed invention cannot be considered novel or cannot be considered to involve an inventive step when the document is taken alone
"Y"
document of particular relevance; the claimed invention cannot be considered to involve an inventive step when the document is combined with one or more other such documents, such combination being obvious to a person skilled in the art
"&"
document member of the same patent family

D. INFORMATION ON PATENT FAMILY MEMBERS

Patent document cited in search report Publication date
(day/month/year)
Patent family member(s) Publication date
(day/month/year)
WO 2010022383 A2
25 February 2010
AU 2009282721 A1
BR PI0917853 A2
CA 2735058 A1
CN 102202670 A
CN 103919792 A
DE 112009002063 T5
DK 2365988 T3
DK 2957286 T3
EP 2365988 A2
EP 2957286 A1
EP 3431094 A1
ES 2545887 T3
ES 2699494 T3
GB 2475657 A
GB 2495426 A
GB 2495427 A
GB 2495428 A
HK 1184675 A1
HR P20150955 T1
HR P20181961 T1
HU E025934 T2
HU S1900003 I1
JP 5756403 B2
JP 5883471 B2
JP 6232468 B2
JP 6633583 B2
JP 2012500806 A
JP 2014144977 A
JP 2014144978 A
JP 2016145256 A
JP 2017218454 A
JP 2019065030 A
KR 20110063647 A
KR 20180014845 A
KR 20180133561 A
KR 20200029614 A
LT 2957286 T
LT PA2018004 I1
LT PA2018016 I1
LU C00094 I1
MX 364398 B
NO 2018004 I1
NO 2018041 I1
PL 2365988 T3
PL 2957286 T3
PT 2365988 E
PT 2957286 T
SI 2957286 T1
SM T201500207 T1
US 2011236340 A1
US 2017165292 A1
WO 2010022383 A2
25 February 2010
24 November 2015
25 February 2010
28 September 2011
16 July 2014
12 January 2012
26 October 2015
17 December 2018
21 September 2011
23 December 2015
23 January 2019
16 September 2015
11 February 2019
25 May 2011
10 April 2013
10 April 2013
10 April 2013
25 April 2014
09 October 2015
08 February 2019
30 May 2016
28 February 2019
29 July 2015
15 March 2016
15 November 2017
22 January 2020
12 January 2012
14 August 2014
14 August 2014
12 August 2016
14 December 2017
25 April 2019
13 June 2011
09 February 2018
14 December 2018
18 March 2020
10 December 2018
12 February 2018
10 January 2019
19 December 2018
24 April 2019
17 January 2018
14 December 2018
31 December 2015
29 March 2019
22 October 2015
30 November 2018
31 December 2018
30 October 2015
29 September 2011
15 June 2017
25 February 2010
Name and mailing address of the ISA/:
European Patent Office
P.B. 5818, Patentlaan 2, 2280 HV Rijswijk,
Netherlands
Telephone No. (+31-70)340-2040
Facsimile No. (+31-70)340-3016
Date of the actual completion of the international search:
02 June 2020
Date of mailing of the international search report:
12 June 2020
Authorized officer:
Hoff, Philippe
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