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1. WO2020115048 - ANALOGUES PEPTIDIQUES DE GIP MODIFIÉS


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INTERNATIONAL SEARCH REPORT (ISR)
Part 1:  1  2  3  4  5  6          Part 2:  A  B  C  D  E 
International application No. Applicant's or agent's file reference
PCT/EP2019/083506
International filing date (day/month/year) (Earliest) Priority Date (day/month/year)
03 December 2019 03 December 2018
Applicant
ANTAG THERAPEUTICS APS
FOR FURTHER ACTION: See Form PCT/ISA/220 as well as, where applicable, item 5 below.
This international search report has been prepared by this International Searching Authority and is transmitted to the applicant according to Article 18. A copy is being transmitted to the International Bureau.
It is also accompanied by a copy of each prior art document cited in this report.
1. Basis of the report
a. With regard to the language, the international search was carried out on the basis of:
the international application in the language in which it was filed.
a translation of the international application into                                          which is the language of a translation furnished for the purposes of international search (Rules 12.3(a) and 23.1(b)).
b.
This international search report has been established taking into account the rectification of an obvious mistake authorized by or notified to this Authority under Rule 91 (Rule 43.6bis(a)).
c.
1. With regard to any nucleotide and/or amino acid sequence disclosed in the international application, the international search was carried out on the basis of a sequence listing:
a. forming part of the international application as filed:
in the form of an Annex C/ST.25 text file.
on paper or in the form of an image file.
b. furnished together with the international application under PCT Rule 13ter.1(a) for the purposes of international search only in the form of an Annex C/ST.25 text file.
c. furnished subsequent to the international filing date for the purposes of international search only:
in the form of an Annex C/ST.25 text file (Rule 13ter.1(a)).
on paper or in the form of an image file (Rule 13ter.1(b) and Administrative Instructions, Section 713).
2.
In addition, in the case that more than one version or copy of a sequence listing has been filed or furnished, the required statements that the information in the subsequent or additional copies is identical to that forming part of the application as filed or does not go beyond the application as filed, as appropriate, were furnished.
3.
Additional comments:
2. Certain claims were found unsearchable
3. Unity of invention is lacking
4. Title of the invention
The text is approved as submitted by the applicant.
The text has been established by this Authority to read as follows:
5. Abstract
The text is approved as submitted by the applicant.
The text has been established, according to Rule 38.2, by this Authority as it appears in Box No. IV. The applicant may, within one month from the date of mailing of this international search report, submit comments to this Authority.
6. Drawings
a.
The figure of the drawings to be published with the abstract is Figure No. ____________
as suggested by the applicant.
as selected by this Authority, because the applicant failed to suggest a figure.
as selected by this Authority, because this figure better characterizes the invention.
b.
none of the figures is to be published with the abstract.

A. CLASSIFICATION OF SUBJECT MATTER

     C07K 14/435 (2006.01)i; C07K 14/605 (2006.01)i
According to International Patent Classification (IPC) or to both national classification and IPC

B. FIELDS SEARCHED

Minimum documentation searched (classification system followed by classification symbols):
     C07K
Documentation searched other than minimum documentation to the extent that such documents are included in the fields searched:
Electronic data base consulted during the international search (name of data base and, where practicable, search terms used):
EPO-Internal, CHEM ABS Data, BIOSIS, EMBASE, WPI Data

C. DOCUMENTS CONSIDERED TO BE RELEVANT

Category* Citation of document, with indication, where appropriate, of the relevant passages Relevant to claim No.
(1)
Y
WO 2016034186 A1 (UNIV COPENHAGEN [DK]) 10 March 2016 (2016-03-10)
1-98
cited in the application
the whole document
(2)
Y
WO 2006086769 A2 (AMYLIN PHARMACEUTICALS INC [US]; LEVY ODILE ESTHER [US] ET AL.) 17 August 2006 (2006-08-17)
1-98
figure 12H
(3)
Y
US 2008312157 A1 (LEVY ODILE ESTHER [US] ET AL) 18 December 2008 (2008-12-18)
1-98
figures 5, 12.19
(4)
Y
NIGEL IRWIN ET AL, "GIP(Lys 16 PAL) and GIP(Lys 37 PAL):? Novel Long-Acting Acylated Analogues of Glucose-Dependent Insulinotropic Polypeptide with Improved Antidiabetic Potential", JOURNAL OF MEDICINAL CHEMISTRY,Vol. 49, No. 3, 01 February 2006 (2006-02-01), page 1047-1054,
XP055044385
1-98
figure 1
(5)
X
PATHAK V ET AL, "Antagonism of gastric inhibitory polypeptide (GIP) by palmitoylation of GIP analogues with N- and C-terminal modifications improves obesity and metabolic control in high fat fed mice", MOLECULAR AND CELLULAR ENDOCRINOLOGY,Vol. 401, 01 January 2015 (2015-01-01), page 120-129,
XP029191523
1-10,13-15,19-21,40-43,47,49,50,52-60,64,69-72,74,76-78,85-91,93-95,97,98
the whole document
(6)
X
PATHAK VARUN ET AL, "Sequential induction of beta cell rest and stimulation using stable GIP inhibitor and GLP-1 mimetic peptides improves metabolic control in C57BL/KsJdb/dbmice", 06 June 2015 (2015-06-06), Vol. 58, No. 9, page 2144-2153,
XP035858863
[retrieved on  2015-06-06]
7-15,47,49,50,52-55,59,64,70-72,74,76-78,85-91,93-95,97,98
the whole document
(7)
X,P
WO 2018220123 A1 (UNIV COPENHAGEN [DK]) 06 December 2018 (2018-12-06)
1-98
the whole document
*
Special categories of cited documents:
"A"
document defining the general state of the art which is not considered to be of particular relevance
"D"
document cited by the applicant in the international application
"E"
earlier application or patent but published on or after the international filing date
"L"
document which may throw doubts on priority claim(s) or which is cited to establish the publication date of another citation or other special reason (as specified)
"O"
document referring to an oral disclosure, use, exhibition or other means
"P"
document published prior to the international filing date but later than the priority date claimed
"T"
later document published after the international filing date or priority date and not in conflict with the application but cited to understand the principle or theory underlying the invention
"X"
document of particular relevance; the claimed invention cannot be considered novel or cannot be considered to involve an inventive step when the document is taken alone
"Y"
document of particular relevance; the claimed invention cannot be considered to involve an inventive step when the document is combined with one or more other such documents, such combination being obvious to a person skilled in the art
"&"
document member of the same patent family

D. INFORMATION ON PATENT FAMILY MEMBERS

Patent document cited in search report Publication date
(day/month/year)
Patent family member(s) Publication date
(day/month/year)
WO 2016034186 A1
10 March 2016
EP 3189072 A1
EP 3530671 A2
ES 2685987 T3
PL 3189072 T3
US 2018258152 A1
WO 2016034186 A1
12 July 2017
28 August 2019
15 October 2018
30 April 2019
13 September 2018
10 March 2016
WO 2006086769 A2
17 August 2006
AU 2006213607 A1
BR PI0606992 A2
CA 2597649 A1
EA 200701704 A1
EP 1853627 A2
EP 2390264 A1
EP 2392595 A1
JP 2008530130 A
KR 20070115947 A
NZ 561361 A
SG 159551 A1
US 2009036364 A1
US 2013196913 A1
WO 2006086769 A2
17 August 2006
28 July 2009
17 August 2006
28 February 2008
14 November 2007
30 November 2011
07 December 2011
07 August 2008
06 December 2007
26 February 2010
30 March 2010
05 February 2009
01 August 2013
17 August 2006
US 2008312157 A1
18 December 2008
US 2008312157 A1
US 2013137631 A1
18 December 2008
30 May 2013
WO 2018220123 A1
06 December 2018
AU 2018276434 A1
CA 3064510 A1
CN 110691788 A
WO 2018220123 A1
02 January 2020
06 December 2018
14 January 2020
06 December 2018
Name and mailing address of the ISA/:
European Patent Office
P.B. 5818, Patentlaan 2, 2280 HV Rijswijk,
Netherlands
Telephone No. (+31-70)340-2040
Facsimile No. (+31-70)340-3016
Date of the actual completion of the international search:
14 February 2020
Date of mailing of the international search report:
28 February 2020
Authorized officer:
Pinheiro Vieira, E
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