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1. WO2012023093 - ECHAFAUDAGE POLYMÈRE DE POLYCAPROLACTONE TRIDIMENSIONNEL

Numéro de publication WO/2012/023093
Date de publication 23.02.2012
N° de la demande internationale PCT/IB2011/053586
Date du dépôt international 11.08.2011
CIB
A01K 67/027 2006.01
ANÉCESSITÉS COURANTES DE LA VIE
01AGRICULTURE; SYLVICULTURE; ÉLEVAGE; CHASSE; PIÉGEAGE; PÊCHE
KÉLEVAGE; AVICULTURE; APICULTURE; PISCICULTURE; PÊCHE; OBTENTION D'ANIMAUX, NON PRÉVUE AILLEURS; NOUVELLES RACES D'ANIMAUX
67Élevage ou obtention d'animaux, non prévus ailleurs; Nouvelles races d'animaux
027Nouvelles races de vertébrés
C12N 5/00 2006.01
CCHIMIE; MÉTALLURGIE
12BIOCHIMIE; BIÈRE; SPIRITUEUX; VIN; VINAIGRE; MICROBIOLOGIE; ENZYMOLOGIE; TECHNIQUES DE MUTATION OU DE GÉNÉTIQUE
NMICRO-ORGANISMES OU ENZYMES; COMPOSITIONS LES CONTENANT; CULTURE OU CONSERVATION DE MICRO-ORGANISMES; TECHNIQUES DE MUTATION OU DE GÉNÉTIQUE; MILIEUX DE CULTURE
5Cellules non différenciées humaines, animales ou végétales, p.ex. lignées cellulaires; Tissus; Leur culture ou conservation; Milieux de culture à cet effet
CPC
A01K 2227/105
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
2227Animals characterised by species
10Mammal
105Murine
A01K 2267/0331
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
2267Animals characterised by purpose
03Animal model, e.g. for test or diseases
0331Animal model for proliferative diseases
A01K 67/0271
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
67Rearing or breeding animals, not otherwise provided for; New breeds of animals
027New breeds of vertebrates
0271Chimeric animals, e.g. comprising exogenous cells
A61L 27/18
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for ; grafts or; prostheses or for coating ; grafts or; prostheses
14Macromolecular materials
18obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
A61L 27/3604
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for ; grafts or; prostheses or for coating ; grafts or; prostheses
36containing ingredients of undetermined constitution or reaction products thereof ; , e.g. transplant tissue, natural bone, extracellular matrix
3604characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
A61L 27/56
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for ; grafts or; prostheses or for coating ; grafts or; prostheses
50Materials characterised by their function or physical properties ; , e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
56Porous materials, ; e.g. foams or sponges
Déposants
  • FONDAZIONE T. CAMPANELLA - C.O.E. [IT]/[IT] (AllExceptUS)
  • TASSONE, Pierfrancesco [IT]/[IT] (UsOnly)
  • CAUSA, Filippo [IT]/[IT] (UsOnly)
  • TAGLIAFERRI, Pierosandro [IT]/[IT] (UsOnly)
  • CALIMERI, Teresa [IT]/[IT] (UsOnly)
  • DI MARTINO, Maria, Teresa [IT]/[IT] (UsOnly)
  • BATTISTA, Edmondo [IT]/[IT] (UsOnly)
Inventeurs
  • TASSONE, Pierfrancesco
  • CAUSA, Filippo
  • TAGLIAFERRI, Pierosandro
  • CALIMERI, Teresa
  • DI MARTINO, Maria, Teresa
  • BATTISTA, Edmondo
Mandataires
  • SPADARO, Marco
Données relatives à la priorité
RM2010A00045417.08.2010IT
Langue de publication anglais (EN)
Langue de dépôt anglais (EN)
États désignés
Titre
(EN) THREE-DIMENSIONAL POLY-CAPROLACTONE POLYMERIC SCAFFOLD
(FR) ECHAFAUDAGE POLYMÈRE DE POLYCAPROLACTONE TRIDIMENSIONNEL
Abrégé
(EN)
The present invention refers to a three-dimensional scaffold consisting of poly-ε- caprolactone, optionally pre-coated with human bone marrow stromal cells, to its use for engraftment and in vivo growth of human primary or IL6-dependent multiple myeloma cells in a non-human animal. The present invention also refers to a non-human animal carrying the scaffold of the invention.
(FR)
La présente invention a trait à un échafaudage tridimensionnel qui est constitué de poly-ε-caprolactone, éventuellement préenrobé avec des cellules stromales de moelle osseuse humaine, afin d'être utilisé pour une prise de greffe et une croissance in vivo de cellules de myélome multiple dépendant d'IL6 ou primaire humain chez un animal non humain. La présente invention a également trait à un animal non humain portant l'échafaudage selon la présente invention.
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