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1. WO2011112969 - DÉRIVÉS DE POLY(ÉTHYLÈNEGLYCOL) POUR CHIMIE CLICK SANS MÉTAL

Numéro de publication WO/2011/112969
Date de publication 15.09.2011
N° de la demande internationale PCT/US2011/028153
Date du dépôt international 11.03.2011
CIB
A01N 31/14 2006.1
ANÉCESSITÉS COURANTES DE LA VIE
01AGRICULTURE; SYLVICULTURE; ÉLEVAGE; CHASSE; PIÉGEAGE; PÊCHE
NCONSERVATION DE CORPS HUMAINS OU ANIMAUX OU DE VÉGÉTAUX, OU DE PARTIES DE CEUX-CI; BIOCIDES, p.ex. EN TANT QUE DÉSINFECTANTS, PESTICIDES OU HERBICIDES; PRODUITS REPOUSSANT OU ATTIRANT LES ANIMAUX NUISIBLES; RÉGULATEURS DE CROISSANCE DES VÉGÉTAUX
31Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés organiques de l'oxygène ou du soufre
08l'atome d'oxygène ou de soufre étant lié directement à un système cyclique aromatique
14Ethers
A61K 31/08 2006.1
ANÉCESSITÉS COURANTES DE LA VIE
61SCIENCES MÉDICALE OU VÉTÉRINAIRE; HYGIÈNE
KPRÉPARATIONS À USAGE MÉDICAL, DENTAIRE OU POUR LA TOILETTE
31Préparations médicinales contenant des ingrédients actifs organiques 
075Ethers ou acétals
08acycliques, p.ex. paraformaldéhyde
CPC
A61K 47/60
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
51the non-active ingredient being a modifying agent
56the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
59obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
60the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
C08G 65/2606
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
65Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
02from cyclic ethers by opening of the heterocyclic ring
26from cyclic ethers and other compounds
2603the other compounds containing oxygen
2606containing hydroxyl groups
C08G 65/2618
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
65Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
02from cyclic ethers by opening of the heterocyclic ring
26from cyclic ethers and other compounds
2618the other compounds containing nitrogen
C08G 65/329
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
65Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
02from cyclic ethers by opening of the heterocyclic ring
32Polymers modified by chemical after-treatment
329with organic compounds
C08G 65/33396
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
65Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
02from cyclic ethers by opening of the heterocyclic ring
32Polymers modified by chemical after-treatment
329with organic compounds
333containing nitrogen
33396having oxygen in addition to nitrogen
C08G 65/3356
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
65Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
02from cyclic ethers by opening of the heterocyclic ring
32Polymers modified by chemical after-treatment
329with organic compounds
335containing phosphorus
3356having nitrogen in addition to phosphorus
Déposants
  • INTEZYNE TECHNOLOGIES, INC. [US]/[US] (AllExceptUS)
  • SILL, Kevin N. [US]/[US] (UsOnly)
  • CARDOEN, Gregoire [FR]/[US] (UsOnly)
Inventeurs
  • SILL, Kevin N.
  • CARDOEN, Gregoire
Mandataires
  • NIHAN, Danielle M.
Données relatives à la priorité
61/312,84211.03.2010US
Langue de publication Anglais (en)
Langue de dépôt anglais (EN)
États désignés
Titre
(EN) POLY(ETHYLENE GLYCOL) DERIVATIVES FOR METAL-FREE CLICK CHEMISTRY
(FR) DÉRIVÉS DE POLY(ÉTHYLÈNEGLYCOL) POUR CHIMIE CLICK SANS MÉTAL
Abrégé
(EN) The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof.
(FR) La présente invention concerne des polymères bifonctionnels, leurs procédés de préparation et des intermédiaires à cet effet. Ces composés peuvent être utilisés dans diverses applications, dont la pégylation de molécules biologiquement actives. L'invention concerne également des procédés d'utilisation desdits composés et des compositions en contenant.
Documents de brevet associés
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