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1. WO2008103367 - PROCÉDÉ PERMETTANT D'ASSEMBLER DES BIBLIOTHÈQUES CHIMIQUES D'UNE GRANDE PURETÉ, ET COMPOSÉS PROAPOPTOTIQUES DÉCOUVERTS GRÂCE À CE PROCÉDÉ

Numéro de publication WO/2008/103367
Date de publication 28.08.2008
N° de la demande internationale PCT/US2008/002203
Date du dépôt international 20.02.2008
CIB
C07H 21/00 2006.01
CCHIMIE; MÉTALLURGIE
07CHIMIE ORGANIQUE
HSUCRES; LEURS DÉRIVÉS; NUCLÉOSIDES; NUCLÉOTIDES; ACIDES NUCLÉIQUES
21Composés contenant au moins deux unités mononucléotide comportant chacune des groupes phosphate ou polyphosphate distincts liés aux radicaux saccharide des groupes nucléoside, p.ex. acides nucléiques
CPC
C07D 209/14
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
209Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
02condensed with one carbocyclic ring
04Indoles; Hydrogenated indoles
10with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
C07D 209/34
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
209Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
02condensed with one carbocyclic ring
04Indoles; Hydrogenated indoles
30with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
32Oxygen atoms
34in position 2
C07D 209/52
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
209Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
02condensed with one carbocyclic ring
52condensed with a ring other than six-membered
C07D 211/78
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
211Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
04with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
68having one double bond between ring members or between a ring member and a non-ring member
72with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
78Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
C07D 403/12
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
403Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
02containing two hetero rings
12linked by a chain containing hetero atoms as chain links
C07D 405/14
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
405Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
14containing three or more hetero rings
Déposants
  • KOZMIN, Sergey [RU]/[US]
  • CUI, Jiayue [CN]/[US]
  • MATSUMOTO, Kenji [JP]/[US]
  • LEE, Hajoong [KR]/[US]
Inventeurs
  • KOZMIN, Sergey
  • CUI, Jiayue
  • MATSUMOTO, Kenji
  • LEE, Hajoong
Mandataires
  • MRKSICH, K., Shannon
Données relatives à la priorité
60/902,59420.02.2007US
Langue de publication anglais (EN)
Langue de dépôt anglais (EN)
États désignés
Titre
(EN) METHOD FOR ASSEMBLING HIGH-PURITY CHEMICAL LIBRARIES, PROAPOPTOTIC COMPOUNDS DISCOVERED BY SAME
(FR) PROCÉDÉ PERMETTANT D'ASSEMBLER DES BIBLIOTHÈQUES CHIMIQUES D'UNE GRANDE PURETÉ, ET COMPOSÉS PROAPOPTOTIQUES DÉCOUVERTS GRÂCE À CE PROCÉDÉ
Abrégé
(EN)
The present disclosure provides novel compounds of the formula (I): wherein R0, R1, R2, R3, R4, R5, and n are as defined in the detailed description. One preferred compound of formula (Vl), referred to as triazatricyclamide A, is disclosed.
(FR)
Cette invention concerne des nouveaux composés représentés par la formule (I): dans cette formule, R0, R1, R2, R3, R4, R5, et n sont tels que définis dans la description détaillée. Cette invention concerne un composé privilégié représenté par la formule (Vl), le triazatricyclamide A.
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