Traitement en cours

Veuillez attendre...

Paramétrages

Paramétrages

1. WO2005007696 - LOCUS D'IMMUNOGLOBULINE HUMANISES

Numéro de publication WO/2005/007696
Date de publication 27.01.2005
N° de la demande internationale PCT/US2004/023226
Date du dépôt international 15.07.2004
CIB
C07K 16/46 2006.01
CCHIMIE; MÉTALLURGIE
07CHIMIE ORGANIQUE
KPEPTIDES
16Immunoglobulines, p.ex. anticorps monoclonaux ou polyclonaux
46Immunoglobulines hybrides
CPC
A01K 2207/15
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
2207Modified animals
15Humanized animals
A01K 2217/00
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
2217Genetically modified animals
A01K 2227/105
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
2227Animals characterised by species
10Mammal
105Murine
A01K 2227/107
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
2227Animals characterised by species
10Mammal
107Rabbit
A01K 2267/01
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
2267Animals characterised by purpose
01Animal expressing industrially exogenous proteins
A01K 67/0278
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
67Rearing or breeding animals, not otherwise provided for; New breeds of animals
027New breeds of vertebrates
0275Genetically modified vertebrates, e.g. transgenic
0278Humanized animals, e.g. knockin
Déposants
  • THERAPEUTIC HUMAN POLYCLONALS, INC. [US/US]; 2105 Landings Drive Mountain View, CA 94043, US (AllExceptUS)
  • BUELOW, Roland [DE/US]; US (UsOnly)
  • VAN SCHOOTEN, Wim [NL/US]; US (UsOnly)
Inventeurs
  • BUELOW, Roland; US
  • VAN SCHOOTEN, Wim; US
Mandataires
  • DREGER, Ginger, R.; Heller, Ehrman, White & McAuliffe LLP 275 Middlefield Road Menlo Park, CA 94025-3506, US
Données relatives à la priorité
60/487,73315.07.2003US
Langue de publication anglais (EN)
Langue de dépôt anglais (EN)
États désignés
Titre
(EN) HUMANIZED IMMUNOGLOBULIN LOCI
(FR) LOCUS D'IMMUNOGLOBULINE HUMANISES
Abrégé
(EN)
The present invention concerns methods and means to produce humanized antibodies from transgenic non-human animals. The invention specifically relates to novel immunoglobulin heavy and light chain constructs, recombination and transgenic vectors useful in making transgenic non-human animals expressing humanized antibodies, transgenic animals, and humanized immunoglobulin preparations.
(FR)
L'invention se rapporte à des procédés et des moyens de production d'anticorps à partir d'animaux non humains transgéniques. Cette invention porte notamment sur des constructions de chaînes lourdes et légères d'immunoglobuline, sur des vecteurs de recombinaison et des vecteurs transgéniques utiles dans la fabrication d'animaux non humains transgéniques exprimant des anticorps humanisés, sur des animaux transgéniques, et sur des préparations d'immunoglobuline humanisées.
Autres publications associées
Dernières données bibliographiques dont dispose le Bureau international