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1. WO2005002572 - METHODES D'UTILISATION DE COMPOSES [3.2.0] HETEROCYCLIQUES ET D'ANALOGUES CORRESPONDANTS

Numéro de publication WO/2005/002572
Date de publication 13.01.2005
N° de la demande internationale PCT/US2004/019543
Date du dépôt international 18.06.2004
CIB
A61K 31/407 2006.01
ANÉCESSITÉS COURANTES DE LA VIE
61SCIENCES MÉDICALE OU VÉTÉRINAIRE; HYGIÈNE
KPRÉPARATIONS À USAGE MÉDICAL, DENTAIRE OU POUR LA TOILETTE
31Préparations médicinales contenant des ingrédients actifs organiques 
33Composés hétérocycliques
395ayant l'azote comme hétéro-atome d'un cycle, p.ex. guanéthidine ou rifamycines
40ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p.ex. sulpiride, succinimide, tolmétine, buflomédil
407condensés avec des systèmes hétérocycliques, p.ex. kétorolac, physostigmine
CPC
A61K 31/407
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
407condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
A61P 11/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
06Antiasthmatics
A61P 17/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
06Antipsoriatics
A61P 19/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
02for joint disorders, e.g. arthritis, arthrosis
Y02A 50/409
YSECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
50in human health protection
30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
38Medical treatment of vector-borne diseases characterised by the agent
408the vector-borne disease being caused by a protozoa
409of the genus Leishmania i.e. Leishmaniasis, Sand-fly fever, phlebotomus fever, kala-azar, black fever or Dumdum fever
Y02A 50/411
YSECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
50in human health protection
30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
38Medical treatment of vector-borne diseases characterised by the agent
408the vector-borne disease being caused by a protozoa
411of the genus Plasmodium, i.e. Malaria
Déposants
  • NEREUS PHARMACEUTICALS, INC. [US/US]; 10480 Wateridge Circle San Diego, CA 92121, US (AllExceptUS)
  • PALLADINO, Michael [US/US]; US (UsOnly)
  • NEUTEBOOM, Saskia, Theodora, Cornelia [NL/US]; US (UsOnly)
  • MACHERLA, Venkata, Rami, Reddy [IN/US]; US (UsOnly)
  • POTTS, Barbara, Christine [US/US]; US (UsOnly)
Inventeurs
  • PALLADINO, Michael; US
  • NEUTEBOOM, Saskia, Theodora, Cornelia; US
  • MACHERLA, Venkata, Rami, Reddy; US
  • POTTS, Barbara, Christine; US
Mandataires
  • HART, Daniel; Knobbe Martens Olson & Bear LLP 2040 Main Street 14th Floor Irvine, CA 92614, US
Données relatives à la priorité
60/480,27020.06.2003US
60/566,95230.04.2004US
Langue de publication anglais (EN)
Langue de dépôt anglais (EN)
États désignés
Titre
(EN) USE OF [3.2.0] HETEROCYCLIC COMPOUNDS AND ANALOGS THEREOF FOR THE TREATMENT OF CANCER, INFLAMMATION AND INFECTIOUS DISEASES
(FR) METHODES D'UTILISATION DE COMPOSES [3.2.0] HETEROCYCLIQUES ET D'ANALOGUES CORRESPONDANTS
Abrégé
(EN)
Disclosed are methods of treating cancer, inflammatory conditions, and/or infectious disease in an animal comprising: administering to the animal, a therapeutically effective amount of a [3.2.0] heterocyclic compound, Preferably a 6-oxa-2-azabicyclo [3.2.0] heptane-3, 7-dione, such as salinosporamide A. The animal is a mammal, preferably a human or a rodent.
(FR)
L'invention concerne des méthodes de traitement du cancer, d'affections inflammatoires et/ou de maladies infectieuses chez un animal. Ces méthodes consistent à administrer à cet animal une dose thérapeutiquement efficace d'un composé hétérocyclique. L'animal est un mammifère, de préférence un être humain ou un rongeur.
Dernières données bibliographiques dont dispose le Bureau international