Traitement en cours

Veuillez attendre...

Paramétrages

Paramétrages

Aller à Demande

1. WO2004099375 - IMMUNOCONJUGUES A PHOTOSENSIBILISATEUR LIE INDIRECTEMENT, LEURS PROCEDES DE PRODUCTION ET D'UTILISATION

Numéro de publication WO/2004/099375
Date de publication 18.11.2004
N° de la demande internationale PCT/US2004/013430
Date du dépôt international 30.04.2004
CIB
A61K 39/00 2006.01
ANÉCESSITÉS COURANTES DE LA VIE
61SCIENCES MÉDICALE OU VÉTÉRINAIRE; HYGIÈNE
KPRÉPARATIONS À USAGE MÉDICAL, DENTAIRE OU POUR LA TOILETTE
39Préparations médicinales contenant des antigènes ou des anticorps
C07K 1/13 2006.01
CCHIMIE; MÉTALLURGIE
07CHIMIE ORGANIQUE
KPEPTIDES
1Procédés généraux de préparation de peptides
13Marquage de peptides
CPC
A61K 41/0057
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
41Medicinal preparations obtained by treating materials with wave energy or particle radiation ; ; Therapies using these preparations
0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
A61K 41/0071
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
41Medicinal preparations obtained by treating materials with wave energy or particle radiation ; ; Therapies using these preparations
0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
0071PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
A61K 41/0076
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
41Medicinal preparations obtained by treating materials with wave energy or particle radiation ; ; Therapies using these preparations
0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
0076PDT with expanded (metallo)porphyrins, i.e. having more than 20 ring atoms, e.g. texaphyrins, sapphyrins, hexaphyrins, pentaphyrins, porphocyanines
A61K 47/6883
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
51the non-active ingredient being a modifying agent
68the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
6835the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
6883Polymer-drug antibody conjugates, e.g. mitomycin-dextran-Ab; DNA-polylysine-antibody complex or conjugate used for therapy
G01N 33/582
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
58involving labelled substances
582with fluorescent label
Déposants
  • THE GENERAL HOSPITAL CORPORATION [US]/[US] (AllExceptUS)
  • HASAN, Tayyaba [US]/[US] (UsOnly)
Inventeurs
  • HASAN, Tayyaba
Mandataires
  • LEAHY, Amy, M.
Données relatives à la priorité
60/466,57430.04.2003US
Langue de publication anglais (EN)
Langue de dépôt anglais (EN)
États désignés
Titre
(EN) INDIRECTLY LINKED PHOTOSENSITIZER IMMUNOCONJUGATES, PROCESSES FOR THE PRODUCTION THEREOF AND METHODS OF USE THEROF
(FR) IMMUNOCONJUGUES A PHOTOSENSIBILISATEUR LIE INDIRECTEMENT, LEURS PROCEDES DE PRODUCTION ET D'UTILISATION
Abrégé
(EN)
The present invention relates to indirectly linked photosensitizer immunoconjugate (PIC) compositions, methods of preparation and the use of the same in photodynamic therapeutic and diagnostic applications. PICs comprising a photosensitizer indirectly linked to an antibody via a PEGylated polyglutamate chain are described.
(FR)
L'invention concerne des compositions d'immunoconjugués (PIC) à photosensibilisateur lié, leurs procédés de préparation et d'utilisation dans des applications thérapeutiques photodynamiques et diagnostiques. Des PIC comprenant un photosensibilisateur lié indirectement à un anticorps par l'intermédiaire d'une chaîne de polyglutamate PEG sont également décrits.
Également publié en tant que
US2007020272
Dernières données bibliographiques dont dispose le Bureau international