Traitement en cours

Veuillez attendre...

Paramétrages

Paramétrages

Aller à Demande

1. WO2004056343 - FORMULATIONS INGERABLES POUR LA REDUCTION TRANSITOIRE NON INVASIVE DU VOLUME GASTRIQUE

Numéro de publication WO/2004/056343
Date de publication 08.07.2004
N° de la demande internationale PCT/US2003/041061
Date du dépôt international 19.12.2003
CIB
A61K 9/00 2006.01
ANÉCESSITÉS COURANTES DE LA VIE
61SCIENCES MÉDICALE OU VÉTÉRINAIRE; HYGIÈNE
KPRÉPARATIONS À USAGE MÉDICAL, DENTAIRE OU POUR LA TOILETTE
9Préparations médicinales caractérisées par un aspect particulier
CPC
A61F 5/003
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
5Orthopaedic methods or devices for non-surgical treatment of bones or joints
0003Apparatus for the treatment of obesity; Anti-eating devices
0013Implantable devices or invasive measures
003inflatable
A61F 5/0036
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
5Orthopaedic methods or devices for non-surgical treatment of bones or joints
0003Apparatus for the treatment of obesity; Anti-eating devices
0013Implantable devices or invasive measures
0036Intragastrical devices
A61K 2800/546
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
2800Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
40Chemical, physico-chemical or functional or structural properties of particular ingredients
54Polymers characterized by specific structures/properties
546Swellable particulate polymers
A61K 31/7088
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7088Compounds having three or more nucleosides or nucleotides
A61K 31/715
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
A61K 31/765
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
74Synthetic polymeric materials
765Polymers containing oxygen
Déposants
  • POLYMORFIX, INC. [US]/[US] (AllExceptUS)
  • BURNETT, Daniel, R. [US]/[US] (UsOnly)
  • EDELMAN, Peter, G. [US]/[US] (UsOnly)
Inventeurs
  • BURNETT, Daniel, R.
  • EDELMAN, Peter, G.
Mandataires
  • WU, Nan
Données relatives à la priorité
60/434,36719.12.2002US
60/468,13106.05.2003US
Langue de publication anglais (EN)
Langue de dépôt anglais (EN)
États désignés
Titre
(EN) INGESTIBLE FORMULATIONS FOR TRANSIENT, NONINVASIVE REDUCTION OF GASTRIC VOLUME
(FR) FORMULATIONS INGERABLES POUR LA REDUCTION TRANSITOIRE NON INVASIVE DU VOLUME GASTRIQUE
Abrégé
(EN)
Provided are ingestible polymeric formulations and oral dosage forms for the reduction of gastric volume in the treatment of overweight and obese patients. The formulation includes an acid-sensitive, gelatin coating over a dehydrated hydrophilic polymer. When ingested, the acid-sensitive coating is quickly dissolved by gastric secretions and the hydrophilic polymer is exposed to the aqueous environment of the gastric milieu. The polymer absorbs water and expands to the point that will not allow the polymer to pass beyond the pyloric valve, and the expanded polymer is therefore trapped in the stomach.
(FR)
L'invention concerne des formulations polymères ingérables et des formes pharmaceutiques orales pour la réduction du volume gastrique, à utiliser dans le cadre du traitement de patients à surcharge pondérale et obèses. Ce type de formulation comprend un revêtement de gélatine sensible aux acides établi sur un polymère hydrophile déshydraté. Une fois ingéré, ledit revêtement est rapidement dissous par les sécrétions gastriques, et le polymère hydrophile est alors exposé à l'environnement aqueux du milieu gastrique. Le polymère absorbe l'eau et subit une expansion jusqu'à ne plus pouvoir franchir la valvule pylorique, moyennant quoi il est prisonnier dans l'estomac.
Dernières données bibliographiques dont dispose le Bureau international