Traitement en cours

Veuillez attendre...

Paramétrages

Paramétrages

1. WO2003007989 - PRODUIT PHARMACEUTIQUE CHIMERIQUE DE CIBLAGE ANTIMICROBIEN

Numéro de publication WO/2003/007989
Date de publication 30.01.2003
N° de la demande internationale PCT/US2002/022695
Date du dépôt international 17.07.2002
Demande présentée en vertu du Chapitre 2 13.02.2003
CIB
A61K 47/48 2006.01
ANÉCESSITÉS COURANTES DE LA VIE
61SCIENCES MÉDICALE OU VÉTÉRINAIRE; HYGIÈNE
KPRÉPARATIONS À USAGE MÉDICAL, DENTAIRE OU POUR LA TOILETTE
47Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. les supports ou les additifs inertes; Agents de ciblage ou de modification chimiquement liés à l’ingrédient actif
48l'ingrédient non actif étant chimiquement lié à l'ingrédient actif, p.ex. conjugués polymère-médicament
C07K 16/12 2006.01
CCHIMIE; MÉTALLURGIE
07CHIMIE ORGANIQUE
KPEPTIDES
16Immunoglobulines, p.ex. anticorps monoclonaux ou polyclonaux
12contre du matériel provenant de bactéries
CPC
A61K 2039/505
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
505comprising antibodies
A61K 47/6809
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
51the non-active ingredient being a modifying agent
68the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
6801Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
6803Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
6807the drug or compound being a sugar, nucleoside, nucleotide, nucleic acid, e.g. RNA antisense
6809Antibiotics, e.g. antitumor antibiotics anthracyclins, adriamycin, doxorubicin or daunomycin
A61K 47/6811
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
51the non-active ingredient being a modifying agent
68the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
6801Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
6803Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
6811the drug being a protein or peptide, e.g. transferrin or bleomycin
A61K 47/6835
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
51the non-active ingredient being a modifying agent
68the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
6835the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
A61K 47/6875
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
51the non-active ingredient being a modifying agent
68the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
6835the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
6875the antibody being a hybrid immunoglobulin
A61P 1/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
Déposants
  • C3 SCIENTIFIC CORPORATION [US/US]; 9706 Fourth Avenue Seattle, WA 98115, US (AllExceptUS)
  • REGENTS OF THE UNIVERSITY OF CALIFORNIA [US/US]; 1111 Franklin Street Oakland, CA 94607-5200, US (AllExceptUS)
  • SHI, Wenyuan [US/US]; US (UsOnly)
  • MORRISON, Sherie, L. [US/US]; US (UsOnly)
  • TRINH, Kham [US/US]; US (UsOnly)
  • WIMS, Letitia [US/US]; US (UsOnly)
  • CHEN, Li [CN/US]; US (UsOnly)
  • ANDERSON, Maxwell, H. [US/US]; US (UsOnly)
  • QI, Fengxia [US/US]; US (UsOnly)
Inventeurs
  • SHI, Wenyuan; US
  • MORRISON, Sherie, L.; US
  • TRINH, Kham; US
  • WIMS, Letitia; US
  • CHEN, Li; US
  • ANDERSON, Maxwell, H.; US
  • QI, Fengxia; US
Mandataires
  • WU, Nan; Gray Cary Ware & Freidenrich LLP 153 Townsend Street Suite 800 San Francisco, CA 94107-1907, US
Données relatives à la priorité
09/910,35819.07.2001US
10/077,62414.02.2002US
Langue de publication anglais (EN)
Langue de dépôt anglais (EN)
États désignés
Titre
(EN) ANTI-MICROBIAL TARGETING CHIMERIC PHARMACEUTICAL
(FR) PRODUIT PHARMACEUTIQUE CHIMERIQUE DE CIBLAGE ANTIMICROBIEN
Abrégé
(EN)
The present invention is based on the discovery of a composition that provides targeted anti-microbial effect. Specifically the composition contains a targeting moiety which recognizes a target microbial organism and an anti-microbial peptide moiety which has anti-microbial activity. In addition, the present invention provides methods of treating a microbial infection, e.g., on mucosal surfaces by using the compositions provided by the present invention.
(FR)
L'invention concerne une composition ayant une activité antimicrobienne ciblée. Plus particulièrement, la composition de l'invention contient un fragment de ciblage qui identifie un organisme microbien cible et un fragment peptidique antimicrobien ayant une activité antimicrobienne. L'invention concerne en outre des méthodes de traitement d'une infection microbienne, par exemple sur des surfaces de muqueuses, qui mettent en oeuvre les compositions de l'invention.
Également publié en tant que
Dernières données bibliographiques dont dispose le Bureau international