WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO1978000011) FORM OF IMPLANT MEDICAMENT AND PREPARATION PROCESS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1978/000011    International Application No.:    PCT/DE1978/000003
Publication Date: 21.12.1978 International Filing Date: 07.06.1978
IPC:
A61K 9/16 (2006.01), A61K 9/20 (2006.01), A61K 9/51 (2006.01)
Applicants:
Inventors:
Priority Data:
7082/77 07.06.1977 CH
Title (EN) FORM OF IMPLANT MEDICAMENT AND PREPARATION PROCESS
(FR) FORME D"IMPLANT MEDICAMENTEUX ET PROCEDE DE PREPARATION
Abstract: front page image
(EN)A form of implant medicament for oral and/or parenteral application having one or more medicaments enclosed in a polymer matrix whereby, under physiological conditions, the matter slowly hydrolyses into non-toxic combinations, that can be eliminated physiologically, and, in doing so, liberates the medicament or medicaments, is formed of the product of polycondensation of a dicarboxylic acid, a hydroxy monocarboxylic acid and/or one physiologically will tolerated amino acid, or made of several of these acids and, if necessary, of one or more of the polyols 1,2-propanediol, inosite, pyridoxal, D-panthenol, pentaerythrite, adonite, and preparation of the implant medicament, and in which the still water soluble polycondensate together with the medicament disperses when stirred in a slightly polar dispersing medium and the condensation of the polycondensate is completed until full water insolubility is reached.
(FR)Forme d"implant medicamenteux pour administration par voie orale et/ou parenterale comportant un ou plusieurs medicaments inclus dans une matrice de polymere. Dans des conditions physiologiques la substance s"hydrolyse lentement en elements non toxiques, physiologiquement eliminables et, ce faisant, libere le ou les medicaments. Elle est le produit de la polycondensation d"un acide dicarboxylique, d"un acide hydroxy monocarboxylique et/ou d"un acide amine bien tolere, ou constituee de plusieurs de ces acides et, si necessaire, d"un ou plusieurs des polyols propanediol-1, 2, inosite, pyridoxal, D-penthenol, pentaerythrite, adonite. Preparation de l"implant medicamenteux consistant a disperser le polycondensat encore soluble dans l"eau avec le medicament par agitation dans un milieu de dispersion legerement polaire, et a poursuivre la condensation du polycondensat jusqu"a l"obtention d"une insolubilite totale dans l"eau.
Designated States:
Publication Language: German (DE)
Filing Language: German (DE)