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A hypodermic syringe is provided having a barrel with a movable plunger therein to inject a fluid through a hollow needle thereof which is housed within a passageway of a needle assembly that is attached to the barrel by ultrasonic welding means or other permanent attaching means. Positioned between sacrificial supports in the needle assembly and the barrel is a deformable base. The deformable base houses an enlarged head of the needle which is in contact with energy storage means within the passageway of the needle assembly. The plunger has a rupturable boot thereon which, upon completion of an injection, contacts a deformable base forcing it downward and severing a sacrificial support means within the needle assembly thereby permitting the base to move the enlarged head of the needle downward, until it is blocked by the passageway. Further movement of the base forces the enlarged needle head from the base and into contact with the rupturable boot. Movement of the base continues until the rupturable boot is ruptured by the enlarged head of the needle and the enlarged head of the needle is released from the base thereby triggering a projection of the needle into a hollow portion of the plunger by transfer of energy from energy storage means. Once inside the plunger, the needle is trapped by its enlarged head within the plunger, and the plunger is locked into the body of the syringe.