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1. KR1020130042990 - INGENANE TYPE DITERPENE COMPOUND SEPARATED FROM AN EUPHORBIA KANSUI ROOT PARTS AND A PHARMACEUTICAL COMPOSITION FOR TREATMENT AND PREVENTION OF VIRUS INFECTION COMPRISING THE SAME

Office
République de Corée
Numéro de la demande 1020110107175
Date de la demande 19.10.2011
Numéro de publication 1020130042990
Date de publication 29.04.2013
Numéro de délivrance 1014062010000
Date de délivrance 12.06.2014
Type de publication B1
CIB
C07C 69/716
CCHIMIE; MÉTALLURGIE
07CHIMIE ORGANIQUE
CCOMPOSÉS ACYCLIQUES OU CARBOCYCLIQUES
69Esters d'acides carboxyliques; Esters de l'acide carbonique ou de l'acide formique halogéné
66Esters d'acides carboxyliques dont le groupe carboxyle estérifié est lié à un atome de carbone acyclique et dont l'un des groupes OH, O-métal, -CHO, céto, éther, acyloxy, des groupes , des groupes ou des groupes se trouve dans la partie acide
67d'acides saturés
716Esters d'acides céto-carboxyliques
A61K 31/22
ANÉCESSITÉS COURANTES DE LA VIE
61SCIENCES MÉDICALE OU VÉTÉRINAIRE; HYGIÈNE
KPRÉPARATIONS À USAGE MÉDICAL, DENTAIRE OU POUR LA TOILETTE
31Préparations médicinales contenant des ingrédients actifs organiques 
21Esters, p.ex. nitroglycérine, sélénocyanates
215d'acides carboxyliques
22d'acides acycliques, p.ex. pravastatine
A61P 31/12
ANÉCESSITÉS COURANTES DE LA VIE
61SCIENCES MÉDICALE OU VÉTÉRINAIRE; HYGIÈNE
PACTIVITÉ THÉRAPEUTIQUE SPÉCIFIQUE DE COMPOSÉS CHIMIQUES OU DE PRÉPARATIONS MÉDICINALES
31Agents anti-infectieux, c. à d. antibiotiques, antiseptiques, chimiothérapeutiques
12Antiviraux
Déposants KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
한국생명공학연구원
Inventeurs OH, SEI RYANG
오세량
KIM, JAE WHA
김재화
LEE, HYEONG KYU
이형규
KHIEV PISETH
키엡, 피셋
KIM, DOO YOUNG
김두영
KIM, JUNG HEE
김정희
SONG, JAE SUNG
송재성
AHN, KYUNG SEOP
안경섭
Mandataires 손민
Titre
(EN) INGENANE TYPE DITERPENE COMPOUND SEPARATED FROM AN EUPHORBIA KANSUI ROOT PARTS AND A PHARMACEUTICAL COMPOSITION FOR TREATMENT AND PREVENTION OF VIRUS INFECTION COMPRISING THE SAME
(KO) 인제난 타입의 디테르펜 화합물 및 이를 포함하는 바이러스 감염 질환의 치료 또는 예방용 약학적 조성물
Abrégé
(EN) PURPOSE: An ingenane type diterpene compound is provided to have activity deriving IFN-γ generation from NK cells, thereby treating and preventing virus infection. CONSTITUTION: A compound is represented by chemical formula 1. A pharmaceutical composition for treatment and prevention of virus infection comprising the same comprises a compound represented by chemical formula 2 as an active ingredient. In chemical formula 2, R1 is H, R2 is H, R3 is OCO-(CH2)10-CH3, and R4 is CO-CH(CH3)-CH(CH3)2; R1 is CO-CH(CH3)-CH(CH3)2, R2 is H, R3 is OCO-(CH2)10-CH3, and R4 is H; R1 is H, R2 is OCO-(CH2)8-CH3, R3 is H, and R4 is H; R1 is CO(CH=CH)-(CH2)4-CH3, R2 is OAc, R3 is H, and R4 is H; R1 is CO-CH(CH3)-CH(CH3)2, R2 is OCO-(CH2)14-CH3, R3 is OCO-(CH2)10-CH3, and R4 is H; or R1 is CO-CH(CH3)-CH(CH3)2, R2 is OH, R3 is OCO-(CH2)10-CH3, and R4 is H. COPYRIGHT KIPO 2013 null
(KO) 본 발명은 감수 유래 인제난 타입의 디테르펜 화합물 및 이를 포함하는 바이러스 감염 질환의 치료 또는 예방용 약학적 조성물에 관한 것으로, 더욱 상세하게는 ()의 뿌리인 감수로부터 분리된 신규한 인제난 타입의 디테르펜 화합물 및 상기 신규 화합물 또는 이외의 다른 감수 유래 인제난 타입의 디테르펜 화합물을 포함하는 바이러스 감염 질환의 치료 또는 예방용 약학적 조성물에 관한 것이다. 이유포르비아 간수이 Euphorbia kansui
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