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1. KR1020060087509 - METHOD OF DIFFERENTIATION FROM EMBRYO-STEM CELL OF PRIMATE TO HEMATOGENOUS CELL

Office République de Corée
Numéro de la demande 1020067003500
Date de la demande 21.02.2006
Numéro de publication 1020060087509
Date de publication 02.08.2006
Type de publication A
CIB
C12N 5/06
CCHIMIE; MÉTALLURGIE
12BIOCHIMIE; BIÈRE; SPIRITUEUX; VIN; VINAIGRE; MICROBIOLOGIE; ENZYMOLOGIE; TECHNIQUES DE MUTATION OU DE GÉNÉTIQUE
NMICRO-ORGANISMES OU ENZYMES; COMPOSITIONS LES CONTENANT; CULTURE OU CONSERVATION DE MICRO-ORGANISMES; TECHNIQUES DE MUTATION OU DE GÉNÉTIQUE; MILIEUX DE CULTURE
5Cellules non différenciées humaines, animales ou végétales, p.ex. lignées cellulaires; Tissus; Leur culture ou conservation; Milieux de culture à cet effet
06Cellules ou tissus animaux
C12N 5/00
CCHIMIE; MÉTALLURGIE
12BIOCHIMIE; BIÈRE; SPIRITUEUX; VIN; VINAIGRE; MICROBIOLOGIE; ENZYMOLOGIE; TECHNIQUES DE MUTATION OU DE GÉNÉTIQUE
NMICRO-ORGANISMES OU ENZYMES; COMPOSITIONS LES CONTENANT; CULTURE OU CONSERVATION DE MICRO-ORGANISMES; TECHNIQUES DE MUTATION OU DE GÉNÉTIQUE; MILIEUX DE CULTURE
5Cellules non différenciées humaines, animales ou végétales, p.ex. lignées cellulaires; Tissus; Leur culture ou conservation; Milieux de culture à cet effet
A01K 67/027
ANÉCESSITÉS COURANTES DE LA VIE
01AGRICULTURE; SYLVICULTURE; ÉLEVAGE; CHASSE; PIÉGEAGE; PÊCHE
KÉLEVAGE; AVICULTURE; APICULTURE; PISCICULTURE; PÊCHE; OBTENTION D'ANIMAUX, NON PRÉVUE AILLEURS; NOUVELLES RACES D'ANIMAUX
67Élevage ou obtention d'animaux, non prévus ailleurs; Nouvelles races d'animaux
027Nouvelles races de vertébrés
CPC
A01K 67/0271
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
67Rearing or breeding animals, not otherwise provided for; New breeds of animals
027New breeds of vertebrates
0271Chimeric animals, e.g. comprising exogenous cells
A01K2227/103
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
2227Animals characterised by species
10Mammal
103Ovine
A01K2227/106
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
2227Animals characterised by species
10Mammal
106Primate
A61K 35/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
Déposants TANABE SEIYAKU CO., LTD.
다나베 세이야꾸 가부시키가이샤
Inventeurs HANAZONO YUTAKA
하나조노 유타카
SASAKI KYOKO
사사키 교코
Mandataires 특허법인코리아나
Données relatives à la priorité JP-P-2003-00208724 25.08.2003 JP
Titre
(EN) METHOD OF DIFFERENTIATION FROM EMBRYO-STEM CELL OF PRIMATE TO HEMATOGENOUS CELL
(KO) 영장류 동물의 배아성 줄기 세포로부터 조혈계 세포로의분화 방법
Abrégé
(EN)

A method of differentiation from embryo-stem cells of primates to hematogenous cells, comprising maintaining embryo-stem cells of primates under conditions suitable for differentiation-induction of hematogenous cells; transplanting obtained cells into a fetus lying in the uterus of pregnant sheep; growing the fetus to birth; administering a primates- specific cytokine to larval sheep; further growing the larval sheep to sheep; and collecting hematogenous cells of primates from the resultant sheep. There are further provided a process for producing hematogenous cells of primates; hematogenous cells produced by the process; and a method of preparing a chimeric sheep capable of producing hematogenous cells of primates, comprising maintaining embryo-stem cells of primates under conditions suitable for differentiation-induction of hematogenous cells; and transplanting obtained cells into a fetus lying in the uterus of pregnant sheep. Thus, means for treating symptoms or diseases needing setup of hematogenous system or action of hematogenous cells can be developed.

© KIPO & WIPO 2007

(KO)
영장류 동물의 배아성 줄기 세포를 조혈계 세포의 분화 유도에 적합한 조건으로 유지하고, 얻어진 세포를 임신한 양 자궁 내의 태아에 이식하고, 그 태아를 생육시켜, 출생에 이르른 새끼 양에게 영장류 동물에게 특이적인 사이토카인을 투여하고, 추가로 그 새끼 양을 생육시켜 얻어진 양으로부터 영장류 동물의 조혈계 세포를 얻는, 영장류 동물의 배아성 줄기 세포로부터 조혈계 세포로의 분화 방법, 영장류 동물의 조혈계 세포 제조 방법, 그 제조 방법에 의해 얻어진 조혈계 세포, 및 영장류 동물의 배아성 줄기 세포를 조혈계 세포의 분화 유도에 적합한 조건으로 유지하고, 얻어진 세포를 임신한 양 자궁 내의 태아에 이식하는 영장류 동물의 조혈계 세포를 생산하는 키메라 양의 제작 방법. 본 발명에 의해, 조혈계의 구축 혹은 조혈 세포의 작용을 필요로 하는 질환 또는 상태의 치료를 위한 수단의 개발이 가능해 진다.

Également publié en tant que
US2007124826