(EN) The present invention provides new compositions and methods for removal of protein aggregates from a sample in a flow-through mode. According to an embodiment of the present invention, a flow-through chromatography method of separating a monomeric proteinof interest from protein aggregates in a sample, the method comprising contacting the sample with a solid support that includes one or more cation exchange binding groups attached thereto, at a density of about 1 to about 30 mM, wherein the solid support selectively binds protein aggregates, thereby to separate the monomeric protein of interest from protein aggregates. COPYRIGHT KIPO 2015
(KO) 본 발명은 샘플로부터 단백질 응집물을 플로우 쓰루 모드로 제거하기 위한 신규 조성물과 방법을 제공한다.
