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1. JP2013510167 - ストレスコピン様ペプチドによる心不全の治療方法

Office
Japon
Numéro de la demande 2012538004
Date de la demande 04.11.2010
Numéro de publication 2013510167
Date de publication 21.03.2013
Type de publication A
CIB
A61K 38/00
ANÉCESSITÉS COURANTES DE LA VIE
61SCIENCES MÉDICALE OU VÉTÉRINAIRE; HYGIÈNE
KPRÉPARATIONS À USAGE MÉDICAL, DENTAIRE OU POUR LA TOILETTE
38Préparations médicinales contenant des peptides
A61P 9/04
ANÉCESSITÉS COURANTES DE LA VIE
61SCIENCES MÉDICALE OU VÉTÉRINAIRE; HYGIÈNE
PACTIVITÉ THÉRAPEUTIQUE SPÉCIFIQUE DE COMPOSÉS CHIMIQUES OU DE PRÉPARATIONS MÉDICINALES
9Médicaments pour le traitement des troubles du système cardiovasculaire
04Agents inotropes, c. à d. stimulants de la contraction cardiaque; Médicaments pour le traitement de l'insuffisance cardiaque
C07K 14/575
CCHIMIE; MÉTALLURGIE
07CHIMIE ORGANIQUE
KPEPTIDES
14Peptides ayant plus de 20 amino-acides; Gastrines; Somatostatines; Mélanotropines; Leurs dérivés
435provenant d'animaux; provenant d'humains
575Hormones
CPC
A61K 38/2228
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
22Hormones
2228Corticotropin releasing factor [CRF] (Urotensin)
A61P 3/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
08for glucose homeostasis
10for hyperglycaemia, e.g. antidiabetics
A61P 9/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
A61P 9/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Déposants ヤンセン ファーマシューティカ エヌ.ベー.
Inventeurs ゲンゴ,ピーター,ジェイ.
サバハ,ハニ,エヌ.
シャンクレイ,ニゲル,ピー.
Mandataires 小林 浩
小林 純子
大森 規雄
鈴木 康仁
Données relatives à la priorité 12612548 04.11.2009 US
61/258,181 04.11.2009 US
Titre
(JA) ストレスコピン様ペプチドによる心不全の治療方法
Abrégé
(JA)

本発明は、ある量のストレスコピン様ペプチドを、心不全の治療方法を必要としている被験者に投与することと、被験者の血漿中に存在する該ペプチドの量を、該被験者の心拍数の実質的増加なしに治療的利益をもたらす濃度に実質的に維持することと、を含む、心不全の新規な治療方法に関する。記方法は、選択的副腎皮質刺激ホルモン放出ホルモン受容体2型(CRHR2)作動薬であるストレスコピン様ペプチドの使用を含む。

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