(EN)
Disclosed are carboxamide, sulfonamide and amine compounds, as well as
pharmaceutical compositions and methods
of use. One embodiment is a compound having the structure in which R1, R2, R4,
D, E, J, T, p, q and x are as described herein.
In certain embodiments, a compound disclosed herein activates the AMPK
pathway, and can be used to treat metabolism-related
disorders and conditions.