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1. BR112021015853 - compostos de tieno[3,2-b]piridin-7-amina para o tratamento de disautonomia familiar

Office
Brésil
Numéro de la demande 112021015853
Date de la demande 10.02.2020
Numéro de publication 112021015853
Date de publication 05.10.2021
Type de publication A2
CIB
C07D 495/00
CCHIMIE; MÉTALLURGIE
07CHIMIE ORGANIQUE
DCOMPOSÉS HÉTÉROCYCLIQUES
495Composés hétérocycliques contenant dans le système condensé au moins un hétérocycle comportant des atomes de soufre comme uniques hétéro-atomes du cycle
A61K 31/00
ANÉCESSITÉS COURANTES DE LA VIE
61SCIENCES MÉDICALE OU VÉTÉRINAIRE; HYGIÈNE
KPRÉPARATIONS À USAGE MÉDICAL, DENTAIRE OU POUR LA TOILETTE
31Préparations médicinales contenant des ingrédients actifs organiques 
A61P 25/00
ANÉCESSITÉS COURANTES DE LA VIE
61SCIENCES MÉDICALE OU VÉTÉRINAIRE; HYGIÈNE
PACTIVITÉ THÉRAPEUTIQUE SPÉCIFIQUE DE COMPOSÉS CHIMIQUES OU DE PRÉPARATIONS MÉDICINALES
25Médicaments pour le traitement des troubles du système nerveux
Déposants PTC THERAPEUTICS, INC.
Inventeurs AMAL DAKKA
GARY MITCHELL KARP
JANA NARASIMHAN
JIASHI WANG
MICHAEL A. ARNOLD
NANJING ZHANG
NIKOLAI A. NARYSHKIN
TOM TUAN LUONG
XIAOYAN ZHANG
Mandataires DANNEMANN, SIEMSEN, BIGLER & IPANEMA MOREIRA
Données relatives à la priorité 62/805,283 13.02.2019 US
Titre
(PT) compostos de tieno[3,2-b]piridin-7-amina para o tratamento de disautonomia familiar
Abrégé
(PT) compostos de tieno[3,2-b]piridin-7-amina para o tratamento de disautonomia familiar.a presente invenção refere-se aos compostos de fórmula (i) úteis para melhorar splicing de pré-mrna em uma célula. em particular, outro aspecto da presente invenção aos compostos de tieno[3,2 b]piridina substituída, formas e composições farmacêuticas dos mesmos e métodos de uso para o tratamento ou melhora de disautonomia familiar.
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