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1. BR112020013546 - derivação eficiente de células-tronco embrionárias pluripotentes estáveis de bovinos

Office Brésil
Numéro de la demande 112020013546
Date de la demande 11.01.2019
Numéro de publication 112020013546
Date de publication 01.12.2020
Type de publication A2
CIB
C12N 5/00
CCHIMIE; MÉTALLURGIE
12BIOCHIMIE; BIÈRE; SPIRITUEUX; VIN; VINAIGRE; MICROBIOLOGIE; ENZYMOLOGIE; TECHNIQUES DE MUTATION OU DE GÉNÉTIQUE
NMICRO-ORGANISMES OU ENZYMES; COMPOSITIONS LES CONTENANT; CULTURE OU CONSERVATION DE MICRO-ORGANISMES; TECHNIQUES DE MUTATION OU DE GÉNÉTIQUE; MILIEUX DE CULTURE
5Cellules non différenciées humaines, animales ou végétales, p.ex. lignées cellulaires; Tissus; Leur culture ou conservation; Milieux de culture à cet effet
CPC
C12N 5/0606
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor;
06Animal cells or tissues; Human cells or tissues
0602Vertebrate cells
0603Embryonic cells
0606Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
C12N 2500/99
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2500Specific components of cell culture medium
99Serum-free medium
C12N 2501/115
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2501Active agents used in cell culture processes, e.g. differentation
10Growth factors
115Basic fibroblast growth factor (bFGF, FGF-2)
C12N 2501/415
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2501Active agents used in cell culture processes, e.g. differentation
40Regulators of development
415Wnt; Frizzeled
A01K 67/0275
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
67Rearing or breeding animals, not otherwise provided for; New breeds of animals
027New breeds of vertebrates
0275Genetically modified vertebrates, e.g. transgenic
A01K 2207/12
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
2207Modified animals
12Animals modified by administration of exogenous cells
Déposants THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
THE SALK INSTITUTE FOR BIOLOGICAL SCIENCE
Inventeurs JUAN CARLOS IZPISUA BELMONTE
JUN WU
MARCELA VILARINO
PABLO JUAN ROSS
YANINA BOGLIOTTI
Mandataires Clarke, Modet Propriedade Intelectual Ltda.
Données relatives à la priorité 62/616,975 12.01.2018 US
Titre
(PT) derivação eficiente de células-tronco embrionárias pluripotentes estáveis de bovinos
Abrégé
(PT)
esta exposição refere-se a células-tronco embrionárias (escs) de ungulados derivadas da massa celular interna de blastocistos pré-implantação ou células pluripotentes a partir de embriões. em perspectivas agrícolas e biomédicas, a derivação de escs estáveis a partir de ungulados domésticos é importante para seleção e testes genômicos, engenharia genética e a provisão de uma ferramenta experimental para estudar doenças humanas. os bovinos são um dos ungulados domésticos mais importantes e são comumente usados para alimentação e biorreatores.

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