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1. AU1999026449 - Use of succinic acid or salts thereof and method of treating insulin resistance

Office Australie
Numéro de la demande 26449/99
Date de la demande 12.11.1998
Numéro de publication 1999026449
Date de publication 03.08.2000
Type de publication A
CIB
A61K 31/194
ANÉCESSITÉS COURANTES DE LA VIE
61SCIENCES MÉDICALE OU VÉTÉRINAIRE; HYGIÈNE
KPRÉPARATIONS À USAGE MÉDICAL, DENTAIRE OU POUR LA TOILETTE
31Préparations médicinales contenant des ingrédients actifs organiques 
185Acides; Leurs anhydrides, halogénures ou sels, p.ex. acides du soufre, acides imidiques, hydrazoniques ou hydroximiques
19Acides carboxyliques, p.ex. acide valproïque
194ayant plusieurs groupes carboxyle, p.ex. acides succinique, maléique ou phtalique
CPC
A61K 31/194
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic, hydroximic acids
19Carboxylic acids, e.g. valproic acid
194having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
Déposants Kolesova, Olga Evgenievna
Pomytkin, Igor Anatolievich
Ukhanova, Tatiyana Jurievna
Verteletsky, Pavel Vasilievich
Inventeurs Kolesova, Olga Evgenievna
Pomytkin, Igor Anatolievich
Ukhanova, Tatiyana Jurievna
Titre
(EN) Use of succinic acid or salts thereof and method of treating insulin resistance
Abrégé
(EN)
The invention relates to the use of succinic acid or pharmaceutically acceptable salts thereof for manufacture of medicaments or nutritional supplements effective for treating of insulin resistance in mammals, preferably in non-insulin dependent diabetic humans. Insulin resistance is associated with disorders such as Non-insulin dependent Diabetes Mellitus (NIDDM) and its chronic complications, gestational diabetes mellitus, impaired glucose tolerance, obesity, aging, atherosclerosis, syndrome X, cardiovascular disease, AIDS, cancer, wasting/cachecxia, sepsis, trauma associated with burns, malnutrition, lupus and other autoimmune diseases, endocrine diseases, hyperuricemia, hyperlipidemia, dyslipidemia, polycystic ovary syndrome or complications arising from athletic activity. The invention provides a method of treating insulin resistance in mammals, preferably in humans, which comprises administering to a mammal in need thereof succinic acid or a pharmaceutically acceptable salts thereof.

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