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1 / 127.537
1.WO/2024/005852AUTOMATED PROVISIONING FOR MANAGING OF CONVERSATIONS ACROSS SERVICE DELIVERY NETWORKS
WO - 04.01.2024
Clasificación Internacional H04M 9/00
HELECTRICIDAD
04TECNICA DE LAS COMUNICACIONES ELECTRICAS
MCOMUNICACIONES TELEFONICAS
9Disposiciones de interconexión no comprendiendo conmutación centralizada
 Nº de solicitud PCT/US2022/045291 Solicitante M3G TECHNOLOGY, INC. Inventor/a MARINARO, Douglas E.
A method for establishing at least three-way conversations between customers, service providers, and brand agents within a service delivery network (SDN) is provided. The method commences with receiving a request from a customer for a service by a brand and collecting metadata associated with the customer. The method continues with receiving identification data associated with a service provider. The service provider is selected by the brand based on at least the metadata. The method further includes initiating a two-way communication channel between the customer and one or more brand agents associated with the brand. The method further includes providing a Uniform Resource Locator to the service provider to join the two-way communication channel. The method further includes initiating an at least three-way conversation between the customer, the service provider, and the one or more brand agents via the two-way communication channel.
2.WO/2024/006842BORDETELLA T CELL EPITOPES, MEGAPOOLS AND USES THEREOF
WO - 04.01.2024
Clasificación Internacional A61K 39/02
ANECESIDADES CORRIENTES DE LA VIDA
61CIENCIAS MEDICAS O VETERINARIAS; HIGIENE
KPREPARACIONES DE USO MEDICO, DENTAL O PARA EL ASEO
39Preparaciones medicinales que contienen antígenos o anticuerpos
02Antígenos bacterianos
 Nº de solicitud PCT/US2023/069274 Solicitante LA JOLLA INSTITUTE FOR IMMUNOLOGY Inventor/a SETTE, Alessandro
The present invention includes compositions, including epitope megapools, and methods for detecting the presence of: a Bordetella or an immune response relevant to a Bordetella infection including T cells responsive to one or more Bordetella peptides or proteins comprising, consisting of, or consisting essentially of: one or more amino acid sequences, fusion proteins, a pool of 2 or more peptides, or polynucleotides that expression the amino acid sequences selected from those set forth in any one of Tables 1-20 (SEQ ID NOS: 1 to 2598). The invention further provides vaccines, diagnostics, therapies, and kits, comprising such proteins or peptides.
3.WO/2024/006827METHODS AND SYSTEMS FOR LIGHT-CONTROLLED SURFACE PATTERNING USING PHOTOMASKS
WO - 04.01.2024
Clasificación Internacional B01J 19/00
BTECNICAS INDUSTRIALES DIVERSAS; TRANSPORTES
01PROCEDIMIENTOS O APARATOS FISICOS O QUIMICOS EN GENERAL
JPROCEDIMIENTOS QUÍMICOS O FÍSICOS, p. ej. CATÁLISIS O QUÍMICA DE LOS COLOIDES; APARATOS ADECUADOS
19Procedimientos químicos, físicos o físico-químicos en general; Aparatos apropiados
 Nº de solicitud PCT/US2023/069258 Solicitante 10X GENOMICS, INC. Inventor/a PRISTINSKI, Denis
Provided in some aspects are methods for light-controlled in situ surface patterning of a substrate using a minimal mask scheme. Systems and kits employing the methods are also disclosed. In some embodiments, a method disclosed herein comprises using photomasks and photoresist for photocontrollable hybridization and/or ligation of nucleic acid molecules, wherein photoresist removal allows hybridization and/or ligation of nucleic acid molecules at the exposed area. A large diversity of barcodes can be created in molecules on the substrate via sequential rounds of light exposure, hybridization, and ligation.
4.WO/2024/006797METHODS AND COMPOSITIONS FOR REFINING FEATURE BOUNDARIES IN MOLECULAR ARRAYS
WO - 04.01.2024
Clasificación Internacional B01J 19/00
BTECNICAS INDUSTRIALES DIVERSAS; TRANSPORTES
01PROCEDIMIENTOS O APARATOS FISICOS O QUIMICOS EN GENERAL
JPROCEDIMIENTOS QUÍMICOS O FÍSICOS, p. ej. CATÁLISIS O QUÍMICA DE LOS COLOIDES; APARATOS ADECUADOS
19Procedimientos químicos, físicos o físico-químicos en general; Aparatos apropiados
 Nº de solicitud PCT/US2023/069221 Solicitante 10X GENOMICS, INC. Inventor/a RAMACHANDRAN IYER, Eswar Prasad
Provided in some aspects are methods for light-controlled in situ surface patterning of a substrate. Compositions such as nucleic acid arrays produced by the methods are also disclosed. Further provided in some aspects are methods for light-controlled in situ refinement of nucleic acid array feature boundaries. In some embodiments, a method disclosed herein comprises using photoresist for photocontrollable removal, blocking, and/or inactivation of nucleic acid molecules at feature boundaries. A large diversity of barcodes can be created in molecules on the substrate via sequential rounds of light exposure, hybridization, ligation, and further interceded and/or followed by one or more rounds of photocontrollable refinement of array feature boundaries, to improve spatial array resolution and sensitivity.
5.WO/2024/006782METHODS AND COMPOSITIONS FOR TREATING PANCREATIC CANCER
WO - 04.01.2024
Clasificación Internacional A61K 31/7105
ANECESIDADES CORRIENTES DE LA VIDA
61CIENCIAS MEDICAS O VETERINARIAS; HIGIENE
KPREPARACIONES DE USO MEDICO, DENTAL O PARA EL ASEO
31Preparaciones medicinales que contienen ingredientes orgánicos activos
70Hidratos de carbono; Azúcares; Sus derivados
7088Compuestos que tienen al menos tres nucleósidos o nucleótidos
7105Acidos ribonucleicos naturales, es decir conteniendo unicamente ribosas unidas a la adenina, la guanina, la citosina, o el uracilo y teniendo enlaces 3'-5' fosfodiester
 Nº de solicitud PCT/US2023/069201 Solicitante SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE Inventor/a KAUFMAN, Randal J.
Methods and compositions related to treating pancreatic cancer are described.
6.WO/2024/253577VIDEO GENERATION METHOD
WO - 12.12.2024
Clasificación Internacional G06N 3/0475
GFISICA
06CALCULO; CONTEO
NSISTEMAS DE COMPUTADORES BASADOS EN MODELOS DE CALCULO ESPECIFICOS
3Sistemas de computadores basados en modelos biológicos
02que utilizan modelos de redes neuronales
04Arquitectura, p. ej. topología de interconexión
0475Redes generativas
 Nº de solicitud PCT/SG2024/050285 Solicitante ALIBABA INNOVATION PRIVATE LIMITED Inventor/a WANG, Jiuniu
Provided in the embodiments of the present disclosure is a video generation method. The method comprises: determining text to be processed, and generating initial noise; inputting the initial noise and said text into a video generation model, and in the video generation model, respectively processing the initial noise and said text in a temporal dimension and a spatial dimension by using a spatio-temporal processing unit, so as to obtain at least two video frame representations and a temporal relationship of the at least two video frame representations, wherein the video generation model is obtained by means of performing training according to a text sample, a video frame representation sample corresponding to the text sample, and a noise-added video frame representation sample, and the noise-added video frame representation sample is obtained by means of adding noise to the video frame representation sample according to sample noise; and according to the at least two video frame representations and the temporal relationship of the at least two video frame representations, determining a target video corresponding to said text. Thus, generation of single video frames and generation of a temporal relationship between the single video frames can be realized, thereby ensuring the inter-frame consistency of the video frames.
7.WO/2024/253607AN EXTENDED DEPTH OF FIELD LENS
WO - 12.12.2024
Clasificación Internacional A61F 2/16
ANECESIDADES CORRIENTES DE LA VIDA
61CIENCIAS MEDICAS O VETERINARIAS; HIGIENE
FFILTROS IMPLANTABLES EN LOS VASOS SANGUINEOS; PROTESIS; DISPOSITIVOS QUE MANTIENEN LA LUZ O QUE EVITAN EL COLAPSO DE ESTRUCTURAS TUBULARES, p. ej. STENTS; DISPOSITIVOS DE ORTOPEDIA, CURA O PARA LA CONTRACEPCION; FOMENTACION; TRATAMIENTO O PROTECCION DE OJOS Y OIDOS; VENDAJES, APOSITOS O COMPRESAS ABSORBENTES; BOTIQUINES DE PRIMEROS AUXILIOS
2Filtros implantables en los vasos sanguíneos; Prótesis, es decir, elementos de sustitución o de reemplazo para partes del cuerpo; Dispositivos para unirlas al cuerpo; Dispositivos para proporcionar permeabilidad o para evitar que colapsen las estructuras tubulares del cuerpo, p. ej. stents
02Prótesis implantables en el cuerpo
14Partes de los ojos, p. ej. cristalinos, implantes de córnea; Ojos artificiales
16Lentes intraoculares
 Nº de solicitud PCT/TR2023/050546 Solicitante VSY BIYOTEKNOLOJI VE ILAC SANAYI A.S. Inventor/a HOLMSTRÖM, Sven Thage Sigvard
Presently disclosed is an ophthalmic multifocal lens providing far, intermediate, and near vision as well as an enhanced depth-of-field. According to multiple embodiments, disclosed EDOF lenses minimize undesired photic phenomena, provide seamless far and intermediate vision, with a plateau of vision connected to far vision rather than isolated sharp intensity peaks, and accommodate various pupil sizes, disclosing lenses with additions above 2D, allow shaping of the addition curve, and maintain sharp far vision under different lighting conditions, with phase-shifting structures that have relatively low height.
8.WO/2024/007022MULTI-TIER DIGITAL BEAMFORMING
WO - 04.01.2024
Clasificación Internacional H04B 7/06
HELECTRICIDAD
04TECNICA DE LAS COMUNICACIONES ELECTRICAS
BTRANSMISION
7Sistemas de radiotransmisión, es decir, utilizando un campo de radiación
02Sistemas que utilizan técnicas de diversidad; Sistemas multi-antena, es decir, transmisión o recepción utilizando múltiples antenas
04utilizando una o más antenas independientes espaciadas
06en la estación de emisión
 Nº de solicitud PCT/US2023/069557 Solicitante INNOPHASE, INC. Inventor/a KAVER, Yaniv
A method and apparatus for multi-tier beamforming are disclosed. The method includes receiving a first-tier beamformed frequency-domain IQ data packet and a plurality of second-tier beamformed frequency-domain IQ data packets at a transceiver integrated circuit (IC) subarray. Each transceiver IC of the transceiver IC subarray (i) forms a multi-tier beamformed frequency-domain IQ data set by combining beamformed frequency-domain IQ data from the first-tier beamformed frequency-domain IQ data packet with beamformed frequency-domain IQ data from selected ones of the second-tier beamformed frequency‑domain IQ data packets, (ii) generates a discrete-time-domain signal from the multi-tier beamformed frequency-domain IQ data set, and (ii) generates a modulated radio frequency (RF) signal from the discrete-time-domain signal. The method further includes transmitting a multi-tier beamformed signal by transmitting respective modulated RF signals from the transceiver ICs of the transceiver IC subarray via a corresponding adjacent antenna element subarray.
9.WO/2024/006947SURFACE DISPLAYED FUSION PROTEINS
WO - 04.01.2024
Clasificación Internacional C40B 40/02
CQUIMICA; METALURGIA
40TECNOLOGIA COMBINATORIA
BQUIMICA COMBINATORIA; BIBLIOTECAS, p. ej. QUIMIOTECAS
40Bibliotecas per se, p. ej. arrays, mezclas
02Bibliotecas contenidas en o exhibidas por microorganismos, p. ej. bacterias o células animales; Bibliotecas contenidas en o exhibidas por vectores, p. ej. plásmidos; Bibliotecas que únicamente contienen microorganismos o vectores
 Nº de solicitud PCT/US2023/069438 Solicitante CLARA FOODS CO. Inventor/a ZHONG, Weixi
The present disclosure provides engineered eukaryotic cells comprising a surface displayed fusion proteins comprising a catalytic domain of an enzyme and an anchoring domain of a glycosylphosphatidylinositol (GPI)-anchored protein and methods of use.
10.WO/2024/006917SYSTEMS AND METHODS FOR A NOVEL IMAGE-BASED MULTI-OMICS AGING CLOCK FOR THE PREDICTION OF REMAINING LIFESPAN
WO - 04.01.2024
Clasificación Internacional G16H 50/30
GFISICA
16TECNOLOGÍAS DE LA INFORMACIÓN Y DE LA COMUNICACIÓN ESPECIALMENTE ADAPTADAS PARA ÁREAS DE APLICACIÓN ESPECÍFICAS
HINFORMÁTICA PARA LA ATENCIÓN SANITARIA, p. ej. TECNOLOGÍAS DE LA INFORMACIÓN Y DE LA COMUNICACIÓN ADAPTADAS ESPECIALMENTE AL TRATAMIENTO O AL PROCESAMIENTO DE DATOS MÉDICOS O DEL SISTEMA SANITARIO
50TIC especialmente adaptadas para el diágnostico médico, la simulación médica o la minería de datos médicos; TIC especialmente adaptadas para la detección, monitorización o modelación de las epidemias o de las pandemias
30para el cálculo de los índices de la salud; para la evaluación de los riesgos de la salud de una persona
 Nº de solicitud PCT/US2023/069388 Solicitante ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA Inventor/a SUTPHIN, George
Systems and methods are disclosed for a multi-omics clock designed to predict remaining lifespan in mammals for the purpose of preclinical drug prioritization.
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