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IC:A61K35/76 AND EN_ALLTXT:(coronavirus OR coronaviruses OR coronaviridae OR coronavirinae OR orthocoronavirus OR orthocoronaviruses OR orthocoronaviridae OR orthocoronavirinae OR betacoronavirus OR betacoronaviruses OR betacoronaviridae OR betacoronavirinae OR sarbecovirus OR sarbecoviruses OR sarbecoviridae OR sarbecovirinae OR "severe acute respiratory syndrome" OR sars OR "2019 ncov" OR covid)

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Análisis

1.WO/2022/175436INFLUENZA VIRUS DEFECTIVE INTERFERING PARTICLES FOR USE IN THE PROPHYLACTIC OR THERAPEUTIC TREATMENT OF CORONAVIRIDAE INFECTION
WO 25.08.2022
Clasificación Internacional A61P 31/14
ANECESIDADES CORRIENTES DE LA VIDA
61CIENCIAS MEDICAS O VETERINARIAS; HIGIENE
PACTIVIDAD TERAPEUTICA ESPECIFICA DE COMPUESTOS QUIMICOS O DE PREPARACIONES MEDICINALES
31Antiinfecciosos, es decir antibióticos, antisépticos, quimioterápicos
12Antivirales
14para virus ARN
Nº de solicitud PCT/EP2022/054047 Solicitante MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. Inventor/a KUPKE, Sascha
The present invention relates in a first aspect to the use of influenza virus defective interfering particles in the prophylactic or therapeutic treatment of coronaviridae infection. In particular, it has been recognized that defective interfering particles of influenza A have beneficial effects in the treatment of SARS coronavirus infection, in particular, SARS-CoV-2 infection. Further, the present invention relates to a pharmaceutical composition for use in treating coronaviridae infection, in particular SARS-CoV-2. In a further aspect, methods for the prophylactic or therapeutic treatments of coronaviridae based on the administration of DIFs are disclosed.
2.WO/2021/216467A NANO-ENABLED VACCINATION APPROACH FOR CORONAVIRUS DISEASE (COVID-19) AND OTHER VIRAL DISEASES
WO 28.10.2021
Clasificación Internacional A61K 31/7088
ANECESIDADES CORRIENTES DE LA VIDA
61CIENCIAS MEDICAS O VETERINARIAS; HIGIENE
KPREPARACIONES DE USO MEDICO, DENTAL O PARA EL ASEO
31Preparaciones medicinales que contienen ingredientes orgánicos activos
70Hidratos de carbono; Azúcares; Sus derivados
7088Compuestos que tienen al menos tres nucleósidos o nucleótidos
Nº de solicitud PCT/US2021/028004 Solicitante THE REGENTS OF THE UNIVERSITY OF CALIFORNIA Inventor/a NEL, Andre, E.
In various embodiments immunogenic nanoparticles are provided that are capable of raising an immune response directed against one or more viral proteins and/or protein fragments. In certain embodiments the immunogenic nanoparticles raise an immune response directed against a virus (e.g., SARS-CoV-2 (2019-nCoV), SARS-CoV-2, and MERS-CoV, and the like). In certain embodiments the immunogenic nanoparticles comprise a nanoparticle formed from one or more biocompatible polymer(s), one or more viral proteins or fragments thereof encapsulated within or attached to the biocompatible polymer(s) where the viral protein or fragment thereof comprises an antigen to which an immune response is to be induced by administration of the immunogenic nanoparticle to a mammal and where the immunogenic nanoparticle further comprises an adjuvant (e.g., a STING agonist).
3.20150275183Human Betacoronavirus lineage C and identification of N-terminal dipeptidyl peptidase as its virus receptor
US 01.10.2015
Clasificación Internacional C12N 7/00
CQUIMICA; METALURGIA
12BIOQUIMICA; CERVEZA; BEBIDAS ALCOHOLICAS; VINO; VINAGRE; MICROBIOLOGIA; ENZIMOLOGIA; TECNICAS DE MUTACION O DE GENETICA
NMICROORGANISMOS O ENZIMAS; COMPOSICIONES QUE LOS CONTIENEN; PROPAGACION, CULTIVO O CONSERVACION DE MICROORGANISMOS; TECNICAS DE MUTACION O DE INGENIERIA GENETICA; MEDIOS DE CULTIVO
7Virus, p. ej. bacteriófagos; Composiciones que los contienen; Su preparación o purificación
Nº de solicitud 14430010 Solicitante Erasmus University Medical Center Rotterdam Inventor/a Bartholomeus Leonardus Haagmans

The invention provides an isolated essentially mammalian positive-sense single stranded RNA virus classifiable as belonging to the Order: Nidovirales; Family: Coronaviridae; Subfamily: Coronavirinae; Genus: Betacoronavirus; and non-Lineage A, non-Lineage B or non-Lineage D, human betacoronavirus. The invention also provides a human virus having a receptor binding domain (RBD) capable of binding to a dipeptidyl peptidase 4. The invention also provides diagnostic means and methods, prophylactic means and methods and therapeutic means and methods to be employed in the diagnosis, prevention and/or treatment of disease, in particular of respiratory disease, in particular of mammals, more in particular in humans.

4.WO/2021/178416IMMUNE-MEDIATED CORONAVIRUS TREATMENTS
WO 10.09.2021
Clasificación Internacional A61K 35/76
ANECESIDADES CORRIENTES DE LA VIDA
61CIENCIAS MEDICAS O VETERINARIAS; HIGIENE
KPREPARACIONES DE USO MEDICO, DENTAL O PARA EL ASEO
35Preparaciones medicinales que contienen sustancias de constitución indeterminada o sus productos de reacción
66Microorganismos o sustancias que provienen de ellos
76Virus; Partículas subvirales; Bacteriófagos
Nº de solicitud PCT/US2021/020490 Solicitante HEAT BIOLOGICS, INC. Inventor/a HUTCHINS, Jeff T.
The present invention provides an expression vector, host cells, methods and kits for the treatment or prevention of a coronavirus infection in a subject.
5.WO/2004/092360THE SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS
WO 28.10.2004
Clasificación Internacional A61K 35/76
ANECESIDADES CORRIENTES DE LA VIDA
61CIENCIAS MEDICAS O VETERINARIAS; HIGIENE
KPREPARACIONES DE USO MEDICO, DENTAL O PARA EL ASEO
35Preparaciones medicinales que contienen sustancias de constitución indeterminada o sus productos de reacción
66Microorganismos o sustancias que provienen de ellos
76Virus; Partículas subvirales; Bacteriófagos
Nº de solicitud PCT/US2004/011710 Solicitante CHIRON CORPORATION Inventor/a RAPPUOLI, Rino
An outbreak of a virulent respiratory virus, now known as Severe Acute Respiratory Syndrome (SARS), was identified in Hong Kong, China and a growing number of countries around the world in 2003. The invention relates to nucleic acids and proteins from the SARS coronavirus. These nucleic acids and proteins can be used in the preparation and manufacture of vaccine formulations, diagnostic reagents, kits, etc. The invention also provides methods for treating SARS by administering small molecule antiviral compounds, as well as methods of identifying potent small molecules for the treatment of SARS.
6.20070286872Live Attenuated Nidovirus Vaccines
US 13.12.2007
Clasificación Internacional A61K 39/12
ANECESIDADES CORRIENTES DE LA VIDA
61CIENCIAS MEDICAS O VETERINARIAS; HIGIENE
KPREPARACIONES DE USO MEDICO, DENTAL O PARA EL ASEO
39Preparaciones medicinales que contienen antígenos o anticuerpos
12Antígenos virales
Nº de solicitud 10553883 Solicitante Vanderbilt University Inventor/a Denison Mark

The present invention is directed live, attenuated Nidovirus vaccines, and in a particular embodiment, to coronavirus vaccines. The vaccine comprises a viral genome encoding a replicase polyprotein having at least one proteinase cleavage site that exhibits reduced or no cleavage. Such viruses show reduced.

7.WO/2022/135683USE OF A BIRNAVIRUS ALONE OR IN COMBINATION THERAPY FOR THE TREATMENT OF A DISEASE CAUSED BY A NIDOVIRUS
WO 30.06.2022
Clasificación Internacional C12N 7/00
CQUIMICA; METALURGIA
12BIOQUIMICA; CERVEZA; BEBIDAS ALCOHOLICAS; VINO; VINAGRE; MICROBIOLOGIA; ENZIMOLOGIA; TECNICAS DE MUTACION O DE GENETICA
NMICROORGANISMOS O ENZIMAS; COMPOSICIONES QUE LOS CONTIENEN; PROPAGACION, CULTIVO O CONSERVACION DE MICROORGANISMOS; TECNICAS DE MUTACION O DE INGENIERIA GENETICA; MEDIOS DE CULTIVO
7Virus, p. ej. bacteriófagos; Composiciones que los contienen; Su preparación o purificación
Nº de solicitud PCT/EP2020/087550 Solicitante PROBIOGEN AG Inventor/a KOVESDI, Imre
The present invention relates to a birnavirus for use in the treatment of a disease caused by a nidovirus. Further, the present invention relates to a combination comprising at least one birnavirus and at least one further active agent for use in the treatment of a disease caused by a nidovirus. Furthermore, the present invention relates to a pharmaceutical composition comprising the birnavirus or the combination for use in the treatment of a disease caused by a nidovirus.
8.WO/2008/062309ANTI-CORONAVIRUS MOLECULES AND THEIR USE IN COMPOSITIONS AND METHODS FOR TREATING AND/OR PREVENTING INFECTION CAUSED BY A CORONAVIRUS
WO 29.05.2008
Clasificación Internacional C07K 14/165
CQUIMICA; METALURGIA
07QUIMICA ORGANICA
KPEPTIDOS
14Péptidos con más de 20 aminoácidos; Gastrinas; Somatostatinas; Melanotropinas; Sus derivados
005de origen vírico
08Virus ARN
165Coronaviridae, p. ej. virus de la bronquitis infecciosa aviar
Nº de solicitud PCT/IB2007/004174 Solicitante HONG-KONG PASTEUR RESEARCH CENTRE Inventor/a NAL-ROGIER, Béatrice, Thérèse, Marie
The present invention relates to the field of coronavirus and more particularly to anti-coronavirus molecules and their use in compositions and methods for treating and/or preventing infection caused by a coronavirus such as the one responsible for SARS. The present invention also relates to a method for screening new anti- coronavirus molecules.
9.WO/2021/210686CORONAVIRUS VACCINE
WO 21.10.2021
Clasificación Internacional A61P 31/14
ANECESIDADES CORRIENTES DE LA VIDA
61CIENCIAS MEDICAS O VETERINARIAS; HIGIENE
PACTIVIDAD TERAPEUTICA ESPECIFICA DE COMPUESTOS QUIMICOS O DE PREPARACIONES MEDICINALES
31Antiinfecciosos, es decir antibióticos, antisépticos, quimioterápicos
12Antivirales
14para virus ARN
Nº de solicitud PCT/JP2021/015773 Solicitante VLP THERAPEUTICS, INC. Inventor/a AKAHATA, Wataru
Provided herein is an isolated polynucleotide, which encodes alphavirus non-structural proteins nsp1, nsp2, nsp3 and nsp4 and a polypeptide comprising a coronavirus protein fused to a signal sequence and/or transmembrane domain. The coronavirus protein may be the receptor binding domain of the S1 subunit of coronavirus spike (S) protein. The polynucleotide such as RNA is useful for as a vaccine against coronavirus infection, especially, COVID-19 infection.
10.20220054601Methods and compositions for treating coronavirus infections
US 24.02.2022
Clasificación Internacional C07K 16/10
CQUIMICA; METALURGIA
07QUIMICA ORGANICA
KPEPTIDOS
16Inmunoglobulinas, p. ej. anticuerpos mono o policlonales
08contra materiales víricos
10de virus ARN
Nº de solicitud 17342897 Solicitante MOREHOUSE SCHOOL OF MEDICINE Inventor/a Michael Powell

The present application relates to a compositions and methods comprising or expressing a HEVAR or MOMO30 protein derived from Momordica balsamina. The HEVAR or MOMO30 protein and/or a nucleic acid encoding the same may be used in methods for treating or preventing viral infections, particularly those caused by coronaviruses, such as SARS-CoV-2.