Parte del contenido de esta aplicación no está disponible en este momento.
Si esta situación persiste, contáctenos aComentarios y contacto
1. (WO2018060466) FINNED ANGIOPLASTY BALLOON
Nota: Texto obtenido mediante procedimiento automático de reconocimiento óptico de caracteres.
Solo tiene valor jurídico la versión en formato PDF

An angioplasty balloon comprising:

an elongate tube of polymeric material having a relaxed delivery configuration and an expanded deployed configuration, the elongate tube comprising :- a proximal neck portion;

a distal neck portion

a main body portion;

a proximal transition portion between the proximal neck portion and the main body portion;

a distal transition portion between the distal neck portion and the main body portion,

a plurality of radially extending fins formed integrally with the elongate tube, the fins extending longitudinally along only a part of the main body portion leaving:- a proximal region and a distal region of the main body portion;

the proximal transition portion and the distal transition portion; and the proximal neck portion and the distal neck portion,

free of fins when the tube is in the expanded configuration.

An angioplasty balloon as claimed in claim 1 wherein the fin-free proximal region of the main body has a length Li of from 0.6 to 1.2 times the nominal diameter of the balloon.

An angioplasty balloon as claimed in claim 1 or 2 wherein the fin-free proximal region of the main body has a length Li of about 0.8 times the nominal diameter of the balloon.

An angioplasty balloon as claimed in claim 1 or 2 wherein the fin-free proximal region of the main body has a length Li of about 0.75 times the nominal diameter of the balloon.

An angioplasty balloon as claimed in claim 1 or 2 wherein the fin-free distal region of the main body has a length L2 of from 0.6 to 1.2 times the nominal diameter of the balloon..

An angioplasty balloon as claimed in any of claims 1 to 5 wherein the fin-free distal region of the main body has a length L2 of about 0.8 times the nominal diameter of the balloon.

An angioplasty balloon as claimed in any of claims 1 to 5 wherein the fin-free distal region of the main body has a length L2 of about 0.75 times the nominal diameter of the balloon.

An angioplasty balloon as claimed in any of claims 1 to 7 wherein the length L3 of the fin preferably equals the balloon nominal length minus about one and a half times the balloon nominal diameter.

An angioplasty balloon as claimed in any of claims 1 to 8 wherein the fins are of generally triangular shape in transverse cross section.

An angioplasty balloon as claimed in claim 9 wherein the height of each of the fins is about 0.75mm or less.

An angioplasty balloon as claimed in claim 9 or 10 wherein the width of each of the fins, at their widest point, is about 0.5mm or less.

An angioplasty balloon as claimed in any of claims 9 to 11 wherein a ratio of the height of the fins to the width of the base of the fins is from about 1.25: 1 to about 1.75: 1.

An angioplasty balloon as claimed in any of claims 1 to 12 wherein the tips of the fins are rounded.

An angioplasty balloon as claimed in any of claims 1 to 13 wherein the fins are spaced equidistant from one another around the exterior of the tube.

An angioplasty balloon as claimed in any of claims 1 to 14 consisting of only three fins.

16. An angioplasty balloon as claimed in any of claims 1 to 15 wherein a distal end of each fin is of generally concave shape in longitudinal cross section.

17. An angioplasty balloon as claimed in any of claims 1 to 16 wherein a proximal end of each fin is of generally convex shape in longitudinal cross section.

18. An angioplasty balloon as claimed in any of claims 1 to 17 wherein the fins have longitudinally spaced- apart interruptions.

19. An angioplasty balloon as claimed in any of claims 1 to 18 wherein the tube is of Nylon material.

20. An angioplasty balloon as claimed in claim 19 wherein the tube is of Nylon 12.

21. An angioplasty balloon comprising:

an elongate tube of polymeric material having a relaxed delivery configuration and an expanded deployed configuration, the elongate tube comprising :- a proximal neck portion;

a distal neck portion

a main body portion;

a proximal transition portion between the proximal neck portion and the main body portion;

a distal transition portion between the distal neck portion and the main body portion,

only three radially extending fins formed integrally with the elongate tube, the fins being spaced circumferentially equidistant from one another around the exterior of the tube, the fins extending longitudinally along only a part of the main body portion leaving:- a proximal region and a distal region of the main body portion;

the proximal transition portion and the distal transition portion; and the proximal neck portion and the distal neck portion, free of fins when the tube is in the expanded configuration.

22. An angioplasty balloon comprising:

an elongate tube of polymeric material having a relaxed delivery configuration and an expanded deployed configuration, the elongate tube comprising :- a proximal neck portion;

a distal neck portion

a main body portion;

a proximal transition portion between the proximal neck portion and the main body portion;

a distal transition portion between the distal neck portion and the main body portion,

a plurality of radially extending fins formed integrally with the elongate tube, the fins extending longitudinally along only a part of the main body portion leaving:- a proximal region and a distal region of the main body portion;

the proximal transition portion and the distal transition portion; and the proximal neck portion and the distal neck portion, free of fins when the tube is in the expanded configuration

wherein the fin-free proximal region of the main body has a length Li of from 0.6 to 1.2 times the nominal diameter of the balloon and wherein the fin-free distal region of the main body has a length L2 of from 0.6 to 1.2 times the nominal diameter of the balloon.

23. An angioplasty balloon comprising:

an elongate tube of polymeric material having a relaxed delivery configuration and an expanded deployed configuration, the elongate tube comprising :- a proximal neck portion;

a distal neck portion

a main body portion;

a proximal transition portion between the proximal neck portion and the main body portion;

a distal transition portion between the distal neck portion and the main body portion,

a plurality of radially extending fins formed integrally with the elongate tube, the fins extending longitudinally along only a part of the main body portion leaving:- a proximal region and a distal region of the main body portion;

the proximal transition portion and the distal transition portion; and the proximal neck portion and the distal neck portion, free of fins when the tube is in the expanded configuration,

wherein the fins are of generally triangular shape in transverse cross section, the height of each of the fins is about 0.75mm or less, the width of each of the fins, at their widest point, is about 0.5mm or less and wherein a ratio of the height of the fins to the width of the base of the fins is from about 1.25: 1 to about 1.75: 1

24. An angioplasty balloon as claimed in any of claims 21 to 23 wherein the length L3 of the fin equals the balloon nominal length minus about one and a half times the balloon nominal diameter.

25. An angioplasty system comprising an angioplasty balloon as claimed in any of claims 1 to 24 and a catheter to which the balloon is mounted, the catheter comprising an outer shaft to which a proximal end of the balloon is mounted and an inner shaft which extends through the balloon wherein the inner tube has at least one radiopaque marker band thereon aligned with the fin-free proximal or distal region of the main body portion of the balloon.

26. An angioplasty system as claimed in claim 25 wherein the inner tube has a distal marker band aligned with the fin-free distal region of the main body portion of the balloon and a proximal marker band aligned with the fin-free proximal region of the main body portion of the balloon.

27. A method of treating a region of stenosis in a vasculature comprising the steps of:

providing an angioplasty system as claimed in claim 25 or 26;

advancing the catheter to a lesion;

with the balloon in the relaxed configuration, advancing the catheter through the lesion so that the fins are aligned with the region of stenosis;

inflating the balloon so that the fins cut into the stenotic material; deflating the balloon and subsequently re-inflating the balloon so that the fins cut further into the stenotic material.

28. A method as claimed in claim 27 wherein the inflation and deflation steps are carried out multiple times as the balloon is located in the region of stenosis.

29. A method as claimed in any of claims 27 or 28 comprising, after angioplasty, deploying a stent at the lesion.