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1 / 16,196
1.1907540IN-SOLUTION ACTIVATION OF FACTOR VII
PT - 04.02.2013
国际分类 C12N 9/64
C化学;冶金
12生物化学;啤酒;烈性酒;果汁酒;醋;微生物学;酶学;突变或遗传工程
N微生物或酶;其组合物;繁殖、保藏或维持微生物;变异或遗传工程;培养基。
9酶,如连接酶(6.);酶原;其组合物;制备、活化、抑制、分离或纯化酶的方法
14水解酶(3.)
48作用在肽键上,如促凝血酶、亮氨酸氨基肽酶(34)
50蛋白酶
64从动物组织得到,如凝乳酶
 申请号 06800183 申请人 BAYER HEALTHCARE LLC 发明人 KREBBER CLAUS M
The present invention is directed to a method for activation of Factor VII to FVIIa in solution.
2.1641607METHOD AND PLANT FOR FORMING CERAMIC SLABS OR TILES OF CONTROLLED THICKNESS
PT - 21.10.2008
国际分类 B28B 3/12
B作业;运输
28加工水泥、黏土或石料
B黏土或其他陶瓷成分的成型;熔渣的成型;含有水泥材料的混合物的成型,例如灰浆
3使用压力机由材料生产成型制品;及其专用压力机
12具有一个或多个辊子加压在材料上
 申请号 04740798 申请人 SACMI 发明人 RIVOLA PIETRO
Method for forming ceramic tiles, comprising the following operative steps: creating a continuous layer of powders on a flexible belt, advancing said belt through a pressing station of continuous type, with which means are associated to laterally retain the powders, and which presses the powders during belt advancement to obtain a coherent article of compacted powders, measuring the thickness of the slab of compacted material and, on the basis of the slab thickness measurement, regulating the powder thickness of the layer before compaction.
3.1924570AZOLE AND THIAZOLE DERIVATIVES AND THEIR USE
PT - 17.12.2010
国际分类 C07D 263/32
C化学;冶金
07有机化学
D杂环化合物(高分子化合物入C08)
263杂环化合物,含有1,3-唑环或氢化1,3-唑环
02不和其他环稠合
30环原子间或环原子与非环原子间有两个或3个双键
32只有氢原子、烃基或取代烃基,直接连在环碳原子上
 申请号 06765253 申请人 PULMAGEN THERAPEUTICS SYNERGY LTD 发明人 FINCH HARRY
Compounds of formula (I) are useful in the treatment of diseases where enhanced M3 receptor activation is implicated, such as respiritory tract diseases: wherein (i) R1 is C1-C6-alkyl or hydrogen; and R2 is hydrogen or a group -R7, -Z-Y-R7, -Z-NR9R10; -Z-CO-NR9R10, -Z-NR9-[AE11]C(O)O-R7, or -Z-C(O)-R7; and R3 is a lone pair, or C1C6-alkyl; or (ii) R1 and R3 together with the nitrogen to which they are attached form a heterocycloalkyl ring, and R2 is a lone pair or a group -R7, -Z-Y-R7, -Z-NR9R10, -Z-CO-NR9R10, -Z-NR9-[AE12]C(O)O-R7; or; -Z-C(O)-R7; or (iii) R1 and R2 together with the nitrogen to which they are attached form a heterocycloalkyl ring, said ring being substituted by a group -Y-R7, -Z-Y-R7, -Z-NR9R10; -Z-CO-NR9R10; -Z-NR9-[AE13]C(O)O-R7; or; -Z-C(O)-R7; and R3 is a lone pair, or C1-C6-aIkyl; R4 and R5 are independently selected from the group consisting of aryl, arytfused-heterocycloalkyl, heteroaryl, C1-C6-alkyl, cycloalkyl; R6 is -OH, C1-C6-alkyl, C1-C6-alkoxy, hydroxy-C1-C6-alkyl, nitrile, a group CONR82 or a hydrogen atom; A is an oxygen or a sulfur atom; X is an alkylene, alkenylene or alkynylene group; R7 is an C1-C6-alkyl, aryl, aryl-fused-cycloalkyl, aryl-ffused-heterocycloalkyl, heteroaryl, aryl(C1-C8-alkyl)-, heteroaryl(C1-C8-alkyl)-, cycloalkyl or heterocycloalkyl group; R8 is C1-C6-alkyl or a hydrogen atom; Z is a C1-C16-alkylene, C2-C16-alkenylene or C2-C16-alkynylene group; Y is a bond or oxygen atom; R9 and R10 are independently a hydrogen atom, C1-C6-alkyl, aryl, aryl-fused-heterocycloalkyl, aryl-fused-cycloalkyl, heteroaryl, aryl(C1-C6-alkyl)-, or heteroaryl(C1-C6-alkyl)- group; or R9 and R10 together with the nitrogen atom to which they are attached form a heterocyclic ring of 48 atoms, optionally containing a further nitrogen or oxygen atom.
4.1926472STABILIZED AND PRESERVED KETOTIFEN OPHTHALMIC COMPOSITIONS
PT - 11.07.2011
国际分类 A61K 9/00
A人类生活必需
61医学或兽医学;卫生学
K医用、牙科用或梳妆用的制剂
9以特殊物理形状为特征的医药配制品
 申请号 06802303 申请人 NOVARTIS AG 发明人 TSAO FU-PAO
Ophthalmic compositions comprising ketotifen, a source of hydrogen peroxide providing an amount of hydrogen peroxide of from about 0.001 to about 0.1 % (w/v), one or more ocular-compatible hydrogen peroxide stabilizers, HPMC and CMC, and methods for the treatment and prevention of allergic conjunctivitis using these ophthalmic compositions are provided herein.
5.1926732A PROCESS FOR THE PREPARATION OF CARBAPENEM COMPOUNDS
PT - 27.12.2013
国际分类 C07D 477/20
C化学;冶金
07有机化学
D杂环化合物(高分子化合物入C08)
477杂环化合物,含有1-氮杂二环庚烷环系,即含下式环系的化合物:,例如碳代青霉素,沙纳霉素;这类环系进一步稠合,例如与含氧、含氮或含硫杂环2,3-稠合
10有氢原子,烃基或取代的烃基,直接连在位置4,并有3个键连杂原子至多1个键连卤素的碳原子,例如酯基或氰基,直接连在位置2
12有氢原子,烃基或取代的烃基,连在位置6
16有杂原子或3个键连杂原子至多1个键连卤素的碳原子,例如酯基或氰基,直接连在位置3
20硫原子
 申请号 06820743 申请人 RANBAXY LAB LTD 发明人 TEWARI NEERA
6.1928240TRIAZOLE-BASED FUNGICIDAL MIXTURES
PT - 06.11.2009
国际分类 A01N 43/653
A人类生活必需
01农业;林业;畜牧业;狩猎;诱捕;捕鱼
N杀生剂
43含有杂环化合物的杀生剂、害虫驱避剂或引诱剂,或植物生长调节剂
64具有带3个氮原子作为仅有的环杂原子的环
647三唑,氢化三唑
6531,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
 申请号 06793096 申请人 BASF SE 发明人 STIERL REINHARD
Fungizide Mischungen, enthaltend (1) Epoxiconazol der Formel (I) oder dessen Salze oder Addukte und (2) Tebuconazol der Formel (II) oder dessen Salze oder Addukte in einer synergistisch wirksamen Menge, Verfahren zur Bekämpfung von Schadpilzen mit Mischungen aus einer Verbindung (I) und mindestens einem Wirkstoff (II) und die Verwendung einer Verbindung (I) mit Wirkstoffen (II) zur Herstellung derartiger Mischungen sowie Mittel, die diese Mischungen enthalten.
7.1928872NOVEL SULPHONYLPYRROLES AS INHIBITORS OF HDAC
PT - 25.05.2012
国际分类 C07D 417/14
C化学;冶金
07有机化学
D杂环化合物(高分子化合物入C08)
417杂环化合物,含两个或更多个杂环、至少有1个环有氮原子和硫原子作为仅有的杂环原子,C07D415/00组不包含的
14含有3个或更多个杂环
 申请号 06793379 申请人 4SC AG 发明人 HUMMEL ROLF-PETER
Compounds of a certain formula (I), in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, as well as salts thereof are novel effective HDAC inhibitors.
8.1937575CONVEYOR BELT WITH OVERLAPPING PLANAR SURFACE PLATES
PT - 18.03.2013
国际分类 B65G 17/06
B作业;运输
65输送;包装;贮存;搬运薄的或细丝状材料
G运输或贮存装置,例如装载或倾卸用输送机、车间输送机系统或气动管道输送机
17具有环形牵引元件,如链条的输送机,牵引元件将运动传递给连续的或基本上连续的载荷运载表面或传递给一系列单个载荷运载体;由链条构成载荷运载表面的环形链输送机
06具有由一系列相互连接的,如纵向连杆、板或平台组成的载荷运载表面
 申请号 06808858 申请人 MAGALDI POWER SPA 发明人 MAGALDI MARIO
The present invention is about an innovative metallic conveyor belt, comprising a metallic net traction element individually supporting a plurality of partially overlapping plates, in such a way to form a continuous planar surface belt that can be of considerable reliability and can be so much sturdy as to resist extreme mechanical and thermal stress. The load bearing planar surface and the absence of vibrations make it a suitable working plane for a plurality of uses, such as the separation by means of one or more deviators and/or channels of different materials or objects, and the transport without shakes of high temperature material, such as mould parts.
9.1947093SUBSTITUTED MORPHOLINE AND THIOMORPHOLINE DERIVATIVES
PT - 22.12.2009
国际分类 C07D 295/12
C化学;冶金
07有机化学
D杂环化合物(高分子化合物入C08)
295杂环化合物,含多亚甲基亚胺环,最少有五元环,3-氮杂二环-壬烷,哌嗪,吗啉或硫吗啉环,仅有氢原子直接连在环碳原子上
04有被杂原子取代的烃基,连在环氮原子上
12被以单键或双键键合的氮原子取代
 申请号 08007169 申请人 LUNDBECK & CO AS H 发明人 ROTTLAENDER MARIO
The present invention relates to morpholine and thiomorpholine derivatives of the general formula I or pharmaceutically acceptable salts thereof, and their use.
10.1977950METHOD FOR EFFECT-RELATED ASSESSMENT OF THE PLACING OF A TRACK
PT - 10.05.2013
国际分类 B61K 9/08
B作业;运输
61铁路
K其他不包括的特别适用于铁路的辅助设备小类索引 有关轨道的装备 润湿,润滑;测试;止动,减速;其他3/00;9/00;7/00;13/00 有关车辆的装备 运动中传送负载、连接、或脱开;断面测量;脱轨,复轨1/00;9/00;5/00 车轮的润湿或润滑;测试3/00;9/00 机车保养11/00 其他13/00
9铁路车辆外形测量器;部件过热的探测或指示;在机车或货车上指示不良轨道断面的装置;轨道记录车的一般设计
08监测线路的测量设备
 申请号 08003150 申请人 DB NETZ AG 发明人 NICKLISCH DIRK
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