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1. (US20170286620) Method and system for microbiome-derived diagnostics and therapeutics

专利局 : 美国
申请号: 15621152 申请日: 13.06.2017
公布号: 20170286620 公布日: 05.10.2017
授权号: 10331857 授权日: 25.06.2019
公布类型: B2
国际专利分类:
G01N 33/48
G06F 19/00
G16B 50/00
C12Q 1/68
C12Q 1/6883
C12Q 1/689
G16H 50/20
G16H 20/10
G16B 99/00
G16B 5/00
G06G 7/58
G PHYSICS
01
用于测量的传感器,如敏感元件
N
借助于测定材料的化学或物理性质来测试或分析材料
33
利用不包括在G01N 1/00至G01N 31/00组中的特殊方法来研究或分析材料
48
生物物质,例如血、尿;血球计数器
G PHYSICS
06
计算;推算;计数
F
电数字数据处理
19
专门适用于特定应用的数字计算或数据处理的设备或方法
[IPC code unknown for G16B 50]
C 化学;冶金
12
包括微生物或酶的生物化学、微生物学、酶学,它们的制备;用其来合成化合物或组合物;涉及微生物或酶的测定或检验方法;变异或遗传工程
Q
包含酶或微生物的测定或检验方法;其所用的组合物或试纸;这种组合物的制备方法;在微生物学方法或酶学方法中的条件反应控制
1
包含酶或微生物的测定或检验方法;其组合物;这种组合物的制备方法
68
包括核酸
[IPC code unknown for C12Q 1/6883][IPC code unknown for C12Q 1/689][IPC code unknown for G16H 50/20][IPC code unknown for G16H 20/10][IPC code unknown for G16B 99][IPC code unknown for G16B 5]
G PHYSICS
06
计算;推算;计数
G
模拟计算机
7
通过改变电量或磁量执行计算操作的器件
48
用于特定的过程、系统或设备的模拟计算机,例如,模拟器
58
用于化学处理过程的
CPC:
C12Q 1/68
G06F 19/3418
C12Q 1/689
C12Q 1/6883
G06F 19/30
G16B 5/00
G16B 50/00
G16B 99/00
G16H 20/10
G16H 50/20
C12Q 2600/118
Y02A 90/26
申请人: uBiome, Inc.
发明人: Zachary Apte
Jessica Richman
Daniel Almonacid
代理人: Kilpatrick Townsend & Stockton LLP
优先权数据:
标题: (EN) Method and system for microbiome-derived diagnostics and therapeutics
摘要: front page image
(EN)

A method for diagnosing and treating an immune microbial dysfunction in a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the immune microbial dysfunction based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset, wherein the characterization is diagnostic of at least one of Crohn's disease, inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), ulcerative colitis, and celiac disease; based upon the characterization, generating a therapy model configured to correct the immune microbial dysfunction; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.