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1. (WO2011005951) ANTIMICROBIAL COATING FOR DERMALLY INVASIVE DEVICES
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CLAIMS

1. An antimicrobial catheter device, comprising:

a catheter having a tip end, a base end, and an extended portion extending therebetween, the catheter further having an outer surface including a transdermal surface and an intravascular surface; and

an antimicrobial agent applied to the transdermal surface of the outer surface, such that following insertion of the catheter into a patient, the antimicrobial agent is interposedly positioned between the transdermal surface and a skin surface of the patient.

2. The device of claim 1, wherein the antimicrobial agent comprises at least one of a water soluble coating, an insoluble coating, a viscous gel coating, a shapeable matrix, and a solid coating.

3. An antimicrobial composition, comprising:

a polymer component;

a fugitive solvent component;

an alcohol component; and

a biocidal agent.

4. The composition of claim 3, wherein the biocidal agent is a non-alcohol based biocidal agent.

5. The composition of claim 3, wherein the polymer component comprises a cationic polymer component.

6. The composition of claim 3, wherein the polymer component is insoluble in water.

7. The composition of claim 3, wherein the polymer component is water soluble.

8. The composition of claim 3, wherein the biocidal agent is present in an amount from approximately 0.01% (w/v) to approximately 10.0% (w/v).

9. The composition of claim 3, wherein the biocidal agent is present in an amount from approximately 0.01% (w/v) to approximately 5.0% (w/v).

10. The composition of claim 3, wherein the polymer component is present in an amount from approximately 0.001% (w/v) to approximately 5.0% (w/v).

11. The composition of claim 6, wherein the polymer component is at least one of cellulosic polymer, chitosan, polyvinyl alcohol, polyvinyl pyrrolidone, polyvinyl acetate, polyurethane.

12. The composition of claim 3, wherein the biocidal agent is at least one of chlorhexidine dihydrochloride, chlorhexidine gluconate, chlorhexidine acetate, chlorhexidine diacetate, triclosan, chloroxylenol, dequalinium chloride, benzethonium chloride, benzalkonium chloride.

13. The composition of claim 3, wherein the alcohol component comprises a lower alcohol having between one and six carbon atoms.

14. The composition of claim 3, wherein the alcohol component is present within the antimicrobial agent in an amount approximately equal to 20% (w/v).

15. The composition of claim 3, wherein the alcohol component comprises a mixture of isopropyl alcohol and ethanol and is present within the antimicrobial agent in an amount from approximately 40% (w/v) to approximately 95% (w/v).

16. The composition of claim 3, wherein the fugitive solvent comprises an organic solvent that is present within the antimicrobial agent in an amount from approximately 20% (w/v) to approximately 95% (w/v).

17. The composition of claim 3, wherein the polymer component comprises a cationic polymer.

18. A method for manufacturing an antimicrobial catheter device, the method comprising:

providing a catheter having an outer surface;

determining a transdermal surface of the outer surface;

determining an intravascular surface of the outer surface; and

coating the transdermal surface with an antimicrobial agent.

19. The method of claim 18, further comprising the step of coating the intravascular surface with an anti-thrombogenic agent.

20. The method of claim 18, wherein the antimicrobial agent comprises a biocompatible bacteria-indicator dye.

21. The method of claim 18, further comprising the step of coating the intravascular surface with an insoluble antimicrobial agent.