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1. (US20120178836) Interconnected porous non-degradable poly(vinyl) alcohol implant and method of manufacture

专利局 : 美国
申请号: 13349365 申请日: 12.01.2012
公布号: 20120178836 公布日: 12.07.2012
授权号: 08557270 授权日: 15.10.2013
公布类型: B2
国际专利分类:
C08J 9/26
C 化学;冶金
08
有机高分子化合物;其制备或化学加工;以其为基料的组合物
J
加工;配料的一般工艺过程;不包括在C08B,C08C,C08F,C08G或C08H小类中的后处理(塑料的加工,如成型入B29)
9
高分子物质加工成多孔或蜂窝状制品或材料:它们的后处理
26
从高分子的组合物或制品中去掉固相,如浸出
申请人: Maher Suzanne A.
New York Society for the Ruptured and Crippled Maintaining the Hospital for Special Surgery
Ng Kenneth
Chen Tony
Wanivenhaus Florian
发明人: Maher Suzanne A.
Ng Kenneth
Chen Tony
Wanivenhaus Florian
代理人: Leason Ellis LLP
优先权数据:
标题: (EN) Interconnected porous non-degradable poly(vinyl) alcohol implant and method of manufacture
摘要: front page image
(EN)

The present invention relates to a method of manufacture of an interconnected porous non-biodegradable polymer implant suitable for implantation into a mammal for the treatment, repair or replacement of defects or injury in musculoskeletal tissue, wherein the mechanical properties of the implant can be controlled by varying the concentration of the non-biodegradable polymer and/or varying the duration and number of freeze-thaw cycles and the interconnected porous non-biodegradable polymer implant has sufficient percent porosity and pore diameter to facilitate integration of cells and attachment within the mammal via ingrowth of surrounding tissue. The present invention also relates to an implant manufactured by the method.