| 摘要： |
(EN)
(12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT)
(19) World Intellectual Property
Organization
International Bureau
(43) International Publication Date
27 October 2016 (27.10.2016) WIPOIPCT
(10) International Publication Number
WO 2016/170112 A1
(51) International Patent Classification:
A01N1/02 (2006.01)
(21) International Application Number:
(22) International Filing Date:
(25) Filing Language:
(26) Publication Language:
PCT/EP2016/05 9005
22 April 2016 (22.04.2016)
English
English
(30) Priority Data:
15164903.5 23 April 2015 (23.04.2015) EP
(71) Applicant: BONE THERAPEUTICS S.A. [BE/BE]; Rue
Auguste Piccard, 37, 6041 Gosselies (BE).
(72) Inventors: BASTIANELLI, Enrico; Avenue de la Libera
tion 41, 1640 Rhode St Genese (BE). BRENNER, Car
men; Rue des Chevaliers 20, 1050 Bruxelles (BE). DEL-
TOUR, Elodie; Rue Fond Vandenbosch 35, 1410 Water
loo (BE).
(74) Agents: MICHALIK, Andrej et al.; De Clercq & Part
ners, E. Gevaertdreef 10a, 9830 Sint-Martens-Latem (BE).
(81) Designated States (unless otherwise indicated, for every
kind of national protection available)'. AE, AG, AL, AM,
AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY,
BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM,
DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT,
HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR,
KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG,
MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM,
PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC,
SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN,
TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
(84) Designated States (unless otherwise indicated, for every
kind of regional protection available)'. ARIPO (BW, GH,
GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ,
TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU,
TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE,
DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU,
LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK,
SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ,
GW, KM, ML, MR, NE, SN, TD, TG).
Declarations under Rule 4.17:
— of inventorship (Rule 4.17(iv))
Published:
— with international search report (Art. 21(3))
— with amended claims (Art. 19(1))
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o CJ (54) Title: IN VITRO PRESERVATION OF THERAPEUTIC CELLS
(57) Abstract: The invention concerns in vitro preservation of living animal cells. In particular, the invention provides a method for
in vitro preservation of cells comprising maintaining adherent mesenchymal stem cells (MSC) or adherent MSC-derived cells in sus
pension in a composition comprising at least 20% v/v human plasma or human serum or a mixture thereof.
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