检索国际和国家专利汇编

1. (WO2009064481) IDENTIFICATION OF NOVEL SUBGROUPS OF HIGH-RISK PEDIATRIC PRECURSOR B ACUTE LYMPHOBLASTIC LEUKEMIA, OUTCOME CORRELATIONS AND DIAGNOSTIC AND THERAPEUTIC METHODS RELATED TO SAME

Pub. No.:    WO/2009/064481    International Application No.:    PCT/US2008/012821
Publication Date: Sat May 23 01:59:59 CEST 2009 International Filing Date: Sat Nov 15 00:59:59 CET 2008
IPC: C12Q 1/68
C12N 15/10
C12N 15/09
Applicants: STC.UNM
SANDIA CORPORATION
WILLMAN, Cheryl, L.
HARVEY, Richard
DAVIDSON, George, S.
WANG, Xuefei
ATLAS, Susan, R.
BEDRICK, Edward, J.
CHEN, Iming, M.
Inventors: WILLMAN, Cheryl, L.
HARVEY, Richard
DAVIDSON, George, S.
WANG, Xuefei
ATLAS, Susan, R.
BEDRICK, Edward, J.
CHEN, Iming, M.
Title: IDENTIFICATION OF NOVEL SUBGROUPS OF HIGH-RISK PEDIATRIC PRECURSOR B ACUTE LYMPHOBLASTIC LEUKEMIA, OUTCOME CORRELATIONS AND DIAGNOSTIC AND THERAPEUTIC METHODS RELATED TO SAME
Abstract:
The present invention relates to the identification of genetic markers patients with high risk B-precursor acute lymphoblastic leukemia (B-ALL) and associated methods and their relationship to therapeutic outcome. The present invention also relates to diagnostic, prognostic and related methods using these genetic markers, as well as kits which provide microchips and/or immunoreagents for performing analysis on leukemia patients.