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1. (WO2018102252) METHODS FOR MAKING BACTERIOCHLORIN MACROCYCLES COMPRISING AN ANNULATED ISOCYCLIC RING AND RELATED COMPOUNDS

Pub. No.:    WO/2018/102252    International Application No.:    PCT/US2017/063251
Publication Date: Fri Jun 08 01:59:59 CEST 2018 International Filing Date: Tue Nov 28 00:59:59 CET 2017
IPC: C07D 487/22
C07D 403/06
C07D 207/333
C07D 403/14
A61K 31/409
A61P 35/00
Applicants: NORTH CAROLINA STATE UNIVERSITY
Inventors: LINDSEY, Jonathan S.
ZHANG, Shaofei
Title: METHODS FOR MAKING BACTERIOCHLORIN MACROCYCLES COMPRISING AN ANNULATED ISOCYCLIC RING AND RELATED COMPOUNDS
Abstract:
Described herein are bacteriochlorins comprising an annulated isocyclic ring. Also described are methods and intermediates for the synthesis of bacteriochlorins comprising an annulated isocyclic ring, and methods of using such bacteriochlorins for, among other things, diagnostic and therapeutic purposes such as, e.g., luminescent compounds in flow cytometry, and/or as active agents in photodynamic therapy (PDT).