Некоторое содержание этого приложения в настоящий момент недоступно.
Если эта ситуация сохраняется, свяжитесь с нами по адресуОтзывы и контакты
1. (WO2018085955) METHOD FOR PRODUCING A SEA URCHIN EXTRACT ENRICHED WITH 1,4-POLYHYDROXYLATED NAPHTHOQUINONES WITH ANTIMICROBIAL AND ANTIOXIDANT ACTIVITY
Новейшие библиограф. данные, касающиеся досье в Международном бюро    Отправить комментарий

№ публикации: WO/2018/085955 № международной заявки: PCT/CL2017/050064
Дата публикации: 17.05.2018 Дата международной подачи: 14.11.2017
МПК:
A61K 35/616 (2015.01)
[IPC code unknown for A61K 35/616]
Заявители:
UNIVERSIDAD TÉCNICA FEDERICO SANTA MARÍA [CL/CL]; Av. España 1680 Valparaíso, 2390123, CL
KNOP LABORATORIOS S.A. [CL/CL]; Av. Industrial 1198 Quilpué, 2420598, CL
Изобретатели:
SEEGER, Michael; CL
STRAHSBURGER, Erwin; CL
GONZÁLEZ, Myriam; CL
CÁRDENAS, Franco; CL
Агент:
ALBA PROFESIONALES; Lota 2267 oficina 211 Providencia Santiago, 8340386, CL
BARRAZA, Carola; CL
Дата приоритета:
2895-201614.11.2016CL
Название (EN) METHOD FOR PRODUCING A SEA URCHIN EXTRACT ENRICHED WITH 1,4-POLYHYDROXYLATED NAPHTHOQUINONES WITH ANTIMICROBIAL AND ANTIOXIDANT ACTIVITY
(FR) MÉTHODE DE PRODUCTION D’UN EXTRAIT D’OURSINS DE MER ENRICHIS EN 1,4-NAPHTHOQUINONES POLYHYDROXYLÉES AYANT DES ACTIVITÉS ANTIMICROBIENNES ET ANTIOXYDANTES
(ES) UN MÉTODO PARA PRODUCIR UN EXTRACTO DE ERIZOS MARINOS ENRIQUECIDO EN 1,4-NAFTOQUINONAS POLIHIDROXILADAS CON ACTIVIDADES ANTIMICROBIANAS Y ANTIOXIDANTES
Реферат:
(EN) The invention relates to a method for obtaining 1,4-polyhydroxylated naphthoquinones from live sea urchins, which comprises the following steps: (a) injecting a saline solution of KCl into the perivisceral coelom of female sea urchins to induce spawning; (b) collecting and grinding the roe to obtain a fine powder; (c) mixing said fine powder with an alcoholic solvent; and (d) separating the alcoholic supernatant comprising the 1,4-polyhydroxylated naphthoquinones in solution. According to the invention, the 1,4-polyhydroxylated naphthoquinones are chosen from: equinochrome A (6-ethyl-2,3,5,7,8-pentahydroxy-1,4-naphthoquinone), spinochrome A (2-acetyl-3,5,6,8-tetrahydroxy-1,4-naphthoquinone), spinochrome B (2,3,5,7-tetrahydroxy-1,4-naphthoquinone), spinochrome C (2-acetyl-3,5,6,7,8-pentahydroxy-1,4-naphthoquinone), spinochrome D (2,3,5,6,8-pentahydroxy-1,4-naphthoquinone), spinochrome E (hexahydroxy-1,4-naphthoquinone) or mixtures thereof.
(FR) La présente invention concerne une méthode pour obtenir des 1,4-naphthoquinones polyhydroxylées à partir d’oursins de mer vivants, laquelle méthode comprend les étapes suivantes: a) l’injection d’une solution saline de KCl dans le coelome périviscéral d’oursins de mer femelles pour induire le frai; b) la collecte des oeufs et le broyage des oeufs en une poudre fine; c) le mélange de ladite poudre fine avec un solvant alcoolique; d) la séparation du surnageant alcoolique qui comprend les 1,4-naphthoquinones polyhydroxylées en solution. Parmi les 1,4-naphthoquinones polyhydroxylées on trouve: l’échinochrome A (6-éthyl-2,3,5,7,8-pentahydroxy1,4-naphthoquinone), le spinochrome A (2-acétyl-3,5,6,8-tétrahydroxy-1,4-naphthoquinone), le spinochrome B (2,3,5,7-tétrahydroxy-1,4-naphthoquinone), le spinochrome C (2- acétyl-3,5,6,7,8- pentahydroxy-1,4-naphthoquinone), le spinochrome D (2,3,5,6,8-pentahydroxy- 1,4-naphthoquinone), le spinochrome E (hexahydroxy-1,4-naphthoquinone) ou leurs mélanges.
(ES) La invención se refiere a un método para obtener 1,4-naftoquinonas polihidroxiladas desde erizos de mar vivos, que comprende las siguientes etapas: a) inyectar una solución salina de KCl en el celoma perivisceral de erizos de mar hembra para inducir el desove; b) recolectar las ovas, y molerlas hasta obtener un polvo fino; c) mezclar dicho polvo fino con un solvente alcohólico; d) separar el sobrenadante alcohólico que comprende las 1,4-naftoquinonas polihidroxiladas en solución. Donde las 1,4-naftoquinonas polihidroxiladas se escogen entre: equinocromo A (6-etil- 2,3,5,7,8-pentahidroxi-1,4-naftoquinona), espinocromo A (2-acetil-3,5,6,8-tetrahidroxi-1,4- naftoquinona), espinocromo B (2,3,5,7-tetrahidroxi-1,4-naftoquinona), espinocromo C (2- acetil-3,5,6,7,8- pentahidroxi-1,4-naftoquinona), espinocromo D (2,3,5,6,8-pentahidroxi- 1,4-naftoquinona), espinocromo E (hexahidroxi-1,4-naftoquinona) o sus mezclas.
Указанные государства: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
Африканская региональная организация промышленной собственности (АРОПС) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Евразийская патентная организация (AM, AZ, BY, KG, KZ, RU, TJ, TM)
Европейское патентное ведомство (ЕПВ) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
Африканская организация интеллектуальной собственности (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Язык публикации: Испанский (ES)
Язык подачи: Испанский (ES)