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1. (WO2001030822) A NOVEL POLYPEPTIDE - HUMAN dUTP PYROPHOSPHATASE 26 AND THE POLYNUCLEOTIDE ENCODING SAID POLYPEPTIDE

Pub. No.:    WO/2001/030822    International Application No.:    PCT/CN2000/000354
Publication Date: Fri May 04 01:59:59 CEST 2001 International Filing Date: Tue Oct 24 01:59:59 CEST 2000
IPC: C12N 9/14
Applicants: SHANGHAI BIO ROAD GENE DEVELOPMENT LTD.

MAO, Yumin

XIE, Yi

Inventors: MAO, Yumin

XIE, Yi

Title: A NOVEL POLYPEPTIDE - HUMAN dUTP PYROPHOSPHATASE 26 AND THE POLYNUCLEOTIDE ENCODING SAID POLYPEPTIDE
Abstract:
The invention discloseS a new kind of polypeptide-human dUTP pyrophosphatase 26 and the polynucleotide encoding said polypeptide and a process for producing the polypeptide by recombinant methods. It also discloseS the method of applying the polypeptide for the treatment of various kinds of diseases, such as cancer, hemopathy, HIV infection, immune diseases and inflammation. The antagonist of the polypeptide and therapeutic use of the same is also disclosed. In addition, it refers to the use of polynucleotide encoding said human dUTP pyrophosphatase 26.