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Resultados 1-4 de 4 para Critérios: ALLNAMES:(Matulis) Organismo(s): all Língua: pt Radicalização: false
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TítuloCtrData de publicação
№ do pedidoRequerenteInventorCIP
5-ARYL-4-(5-SUBSTITUTED 2,4-DIHYDROXYPHENYL)-1,2,3-THIADIAZOLES AS INHIBITORS OF HSP90 CHAPERONE AND THE INTERMEDIATES FOR PRODUCTION THEREOF
WO05.11.2009
PCT/LT2008/000003BIOTECHNOLOGIJOS INSTITUTASMATULIS, Daumantas
C07D 285/06
C QUÍMICA; METALURGIA
07
QUÍMICA ORGÂNICA
D
COMPOSTOS HETEROCÍCLICOS
285
Compostos heterocíclicos contendo anéis tendo átomos de nitrogênio e de enxofre como os únicos heteroátomos do anel, não incluídos nos grupos C07D275/-C07D283/193
01
Anéis de cinco membros
02
Tiadiazóis; Tiadiazóis hidrogenados
04
não-condensados com outro anéis
06
1, 2, 3 - Tiadiazóis; 1, 2, 3 - Tiadazóis hidrogenado
Invention is related to novel compounds - 5-aryl-4-(5-substituted 2,4-dihydroxyphenyl)-1,2,3-thiadiazoles with general formula (I). The compounds can be used in biomedicine as active ingredients in pharmaceutical formulations, because they inhibit Hsp90 chaperone which participate in cancer progression. This invention is also related to new intermediate compounds which are used for the synthesis of thiadiazoles of general formula (I).

BENZIMIDAZO[1,2-C][1,2,3]THIADIAZOL-7-SULFONSÄUREAMIDE ALS CARBOANHYDRASEINHIBITOREN UND ZWISCHENPRODUKTE ZU DEREN HERSTELLUNG
EP06.05.2009
07793796BIOTECHNOLOGIJOS INSTMATULIS DAUMANTAS
C07D 513/04
C QUÍMICA; METALURGIA
07
QUÍMICA ORGÂNICA
D
COMPOSTOS HETEROCÍCLICOS
513
Compostos heterocíclicos contendo no sistema condensado pelo menos um heteroanel, tendo átomos de nitrogênio e enxofre como únicos átomos no heteroanel, não previstos pelos grupos C07D463/, C07D477/243
02
em que o sistema condensado contêm dois heteroanéis
04
Sistemas condensados em orto
The invention is related to novel compounds - benzimidazo[1,2-c][1,2,3]thiadiazole sulfonamides, corresponding to the general formula (I). The compounds can be used in biomedicine as active ingredients in pharmaceutical formulations, because they inhibit enzymes which participate in disease progression such as glaucome. The compounds of formula (I) inhibits enzymes such as carbonic anhydrases and metallo proteinases. This invention is also related to new intermediate compounds which are used for the synthesis of sulfonamides of formula (I).

5-ARYL-4-(5-SUBSTITUTED 2,4-DIHYDROXYFENIL)-1,2,3-THIADIAZOLES AS INHIBITORS OF HSP90 CHAPERONE AND THE INTERMEDIATES FOR PRODUCTION THEREOF
LT25.11.2009
2008035BIOTECHNOLOGIJOS INSTMATULIS DAUMANTAS
C07D 285/00
C QUÍMICA; METALURGIA
07
QUÍMICA ORGÂNICA
D
COMPOSTOS HETEROCÍCLICOS
285
Compostos heterocíclicos contendo anéis tendo átomos de nitrogênio e de enxofre como os únicos heteroátomos do anel, não incluídos nos grupos C07D275/-C07D283/193
Ivention is related to novel compounds - 5-aryl-4-(5-substituted 2,4-dihydroxyphenyl)-1,2,3-thiadiazoles with general formula (I). The compounds can be used in biomedicine as active ingredients in pharmaceutical formulations, because they inhibit Hsp90 chaperone which participate in cancer progression. This invention is also related to new intermediate compounds which are used for the synthesis of thiadiazoles of formula (I).@

BENZIMIDAZO[1,2-C][1,2,3]THIADIAZOL-7-SULFONSÄUREAMIDE ALS CARBOANHYDRASEINHIBITOREN UND ZWISCHENPRODUKTE ZU DEREN HERSTELLUNG
EP06.05.2009
07793796BIOTECHNOLOGIJOS INSTMATULIS DAUMANTAS
C07D 513/04
C QUÍMICA; METALURGIA
07
QUÍMICA ORGÂNICA
D
COMPOSTOS HETEROCÍCLICOS
513
Compostos heterocíclicos contendo no sistema condensado pelo menos um heteroanel, tendo átomos de nitrogênio e enxofre como únicos átomos no heteroanel, não previstos pelos grupos C07D463/, C07D477/243
02
em que o sistema condensado contêm dois heteroanéis
04
Sistemas condensados em orto
The invention is related to novel compounds - benzimidazo[1,2-c][1,2,3]thiadiazole sulfonamides, corresponding to the general formula (I). The compounds can be used in biomedicine as active ingredients in pharmaceutical formulations, because they inhibit enzymes which participate in disease progression such as glaucome. The compounds of formula (I) inhibits enzymes such as carbonic anhydrases and metallo proteinases. This invention is also related to new intermediate compounds which are used for the synthesis of sulfonamides of formula (I).

Resultados 1-4 de 4 para Critérios: ALLNAMES:(Matulis) Organismo(s): all Língua: pt Radicalização: false
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