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1. (WO2018178668) A COMBINATION FOR USE IN THE TREATMENT OF LUNG CANCER

Pub. No.:    WO/2018/178668    International Application No.:    PCT/GB2018/050820
Publication Date: Fri Oct 05 01:59:59 CEST 2018 International Filing Date: Thu Mar 29 01:59:59 CEST 2018
IPC: A61K 45/06
A61K 31/485
A61K 31/592
A61K 31/593
A61K 35/00
Applicants: LDN PHARMA LIMITED
Inventors: DALGLEISH, Angus
LUI, Wai
Title: A COMBINATION FOR USE IN THE TREATMENT OF LUNG CANCER
Abstract:
The invention is based on the finding that co-administration of 6-β-naltrexol alongside vitamin D together with a chemotherapeutic agent, results in a further reduction in lung cancer cell growth. The combination of 6-β-naltrexol with vitamin D results in a greater decrease in the growth of cancer cells compared to the sum of the effects of each agent when administered in isolation.