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1. (WO2011154895) POLYNUCLEOTIDE SEQUENCE, PROCESSES, COMPOSITION AND METHODS THEREOF

Pub. No.:    WO/2011/154895    International Application No.:    PCT/IB2011/052475
Publication Date: Fri Dec 16 00:59:59 CET 2011 International Filing Date: Wed Jun 08 01:59:59 CEST 2011
IPC: C12N 15/30
C07K 14/44
A61K 31/395
G01N 31/00
Applicants: INDIAN INSTITUTE OF SCIENCE
TATU, Utpal
PALLAVI, Rani
YADAV, Suresh, Chander
SINGH, Raj, Kumar
Inventors: TATU, Utpal
PALLAVI, Rani
YADAV, Suresh, Chander
SINGH, Raj, Kumar
Title: POLYNUCLEOTIDE SEQUENCE, PROCESSES, COMPOSITION AND METHODS THEREOF
Abstract:
The present disclosure relates to a polynucleotide sequence coding for a protein of Trypanosoma species. The disclosure further provides processes for inhibiting said protein for treatment of protozoan infections, Malaria and Surra, by Geldanamycin and 17-AAG. The disclosure also relates to processes for identification of these inhibitions, compositions and method of treatments of said infections. Lastly, the present disclosure also relates to examining the efficacy of Hsp90 inhibitor as an anti-malarial and anti-surra agents.