WIPO logo
Celular | Deutsch | English | Español | Français | 日本語 | 한국어 | Русский | 中文 | العربية |
PATENTSCOPE

Pesquisa nas coleções internacionais e nacionais de patentes
World Intellectual Property Organization
Pesquisa
 
Navegação
 
Traduzir
 
Opções
 
Notícias
 
Conectar-se
 
Ajuda
 
Tradução automática
1. (WO2007100578) A SIMPLIFIED QTL MAPPING APPROACH FOR SCREENING AND MAPPING NOVEL MARKERS ASSOCIATED WITH BEEF MARBLING
Dados bibliográficos mais recentes no arquivo da Secretaria Internacional   

№ de pub.:    WO/2007/100578    № do pedido internacional:    PCT/US2007/004485
Data de publicação: 07.09.2007 Data de depósito internacional: 21.02.2007
CIP:
C12Q 1/68 (2006.01), C12P 19/34 (2006.01), G06F 17/00 (2006.01), G06F 17/30 (2006.01), G06F 17/40 (2006.01), G06F 19/00 (2006.01), C07H 21/04 (2006.01)
Requerentes: WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATTION [US/US]; 1610 NE Eastgate Boulevard, Pullman, WA 99163, Edmonton, AB, T6G 2E1 (US) (For All Designated States Except US).
JIANG, Zhihua [CA/US]; (US) (For US Only).
MICHAL, Jennifer, J. [US/US]; (US) (For US Only).
XIAO, Qianjun [CN/US]; (US) (For US Only).
WIBOWO, Tito, A. [ID/US]; (US) (For US Only)
Inventores: JIANG, Zhihua; (US).
MICHAL, Jennifer, J.; (US).
XIAO, Qianjun; (US).
WIBOWO, Tito, A.; (US)
Mandatário: JARECKI-BLACK, Judy; Merial Limited, 3239 Satellite Boulevard, Bldg. 500, Duluth, GA 30096 (US)
Dados da prioridade:
60/775,625 22.02.2006 US
Título (EN) A SIMPLIFIED QTL MAPPING APPROACH FOR SCREENING AND MAPPING NOVEL MARKERS ASSOCIATED WITH BEEF MARBLING
(FR) APPROCHE DE MAPPAGE DE QTL SIMPLIFIÉE POUR LE CRIBLAGE ET LE MAPPAGE DE NOUVEAUX MARQUEURS ASSOCIÉS AU PERSILLAGE DU BOEUF
Resumo: front page image
(EN)Particular aspects provide an inexpensive QTL mapping approach for genome-wide scans of QTL linked markers and for narrowed locations of QTL regions, which may comprise integration of the amplified fragment length polymorphism (AFLP) with DNA pooling and selective genotyping and comparative bioinformatics tools. AFLP simultaneously screens high numbers of loci for polymorphisms and detects many more polymorphic DNA markers than any other PCR based detection systems, and provides for identification of 'responsible mutations' for a QTL. Aspects of the present invention also provide novel compositions and methods based on novel DOPEY2 and/or KIAA1462 single nucleotide polymorphisms such as AAFC03071397.1 :g.72SS/G>C, g. l2925G>A, g. l2951T>C, g.l3013A>G, g.l3125G>A and g.13173OT 'in the DOPEY2 gene and AAFC02113318.1 :,gJ367σ>&Lgr; and g.!372G>A in the KIAAl 462 gene, which may provide novel markers for beef marbling and subcutaneous fat. Additional aspects provide for novel methods which may comprise marker-assisted selection to improve beef marbling and subcutaneous fat in cattle.
(FR)Certains aspects de l'invention concernent une approche de mappage de QTL économique pour des analyses sur tout le génome de marqueurs liés à des QTL et pour des emplacements étroits de régions de QTL, et peuvent consister à intégrer un polymorphisme de longueur de fragments amplifiés (AFLP) avec le génotypage sélectif et le pooling d'ADN et des outils bioinformatiques comparatifs. Le polymorphisme AFLP crible simultanément de grands nombres de loci pour des polymorphismes et détecte beaucoup plus de marqueurs ADN polymorphiques que tout autre système de détection fondé sur la PCR, et permet d'identifier des 'mutations responsables' pour un QTL. D'autres aspects de l'invention concernent également des nouvelles compositions et méthodes faisant intervenir des nouveaux polymorphismes mononucléotidiques DOPEY2 et/ou KIAA1462 de type AAFC03071397.1 :g.72SS/G>C, g. l2925G>A, g. l2951T>C, g.l3013A>G, g.l3125G>A et g.13173OT ' dans le gène DOPEY2 et AAFC02113318.1 :,gJ367σ>&Lgr; et g.!372G>A dans le gène KIAAl 462, qui permettent d'obtenir des nouveaux marqueurs pour le persillage du boeuf et la graisse sous-cutanée. D'autres aspects concernent des nouvelles méthodes de sélection assistée par des marqueurs permettant d'améliorer le persillage du boeuf et la graisse sous-cutanée chez des bovins.
Estados designados: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Língua de publicação: English (EN)
Língua de depósito: English (EN)