WIPO logo
Celular | Deutsch | English | Español | Français | 日本語 | 한국어 | Русский | 中文 | العربية |
PATENTSCOPE

Pesquisa nas coleções internacionais e nacionais de patentes
World Intellectual Property Organization
Pesquisa
 
Navegação
 
Traduzir
 
Opções
 
Notícias
 
Conectar-se
 
Ajuda
 
maximize
Tradução automática
4. (WO2013169361) IRON CHELATORS AS HIV-1 INHIBITORS
Dados bibliográficos mais recentes no arquivo da Secretaria Internacional   

№ de pub.:    WO/2013/169361    № do pedido internacional:    PCT/US2013/031231
Data de publicação: 14.11.2013 Data de depósito internacional: 14.03.2013
CIP:
C07C 337/00 (2006.01), C07C 337/08 (2006.01), A61P 35/00 (2006.01)
Requerentes: HOWARD UNIVERSITY [US/US]; 2400 Sixth Street N.W. Washington, DC 20059 (US)
Inventores: NEKHAI, Sergei; (US).
KOVALSKYY, Dmytro Borisovych; (US)
Mandatário: KRATZ, Rudy; Fitch, Even, Tabin & Flannery 120 S. Lasalle Street Suite 1600 Chicago, IL 60603 (US)
Dados da prioridade:
61/644,842 09.05.2012 US
Título (EN) IRON CHELATORS AS HIV-1 INHIBITORS
(FR) CHÉLATEURS DU FER EN TANT QU'INHIBITEURS DU VIH-1
Resumo: front page image
(EN)The present invention relates to chelator compounds for chelating metal ions. In particular, the present invention relates to (thio)semicarbazone compounds and (thio)hydrazone compounds, such as PpYeT and PpYaT, which are chelators for metal ions, including iron ions. Therapeutic use of such compounds and/ or their metal ion complexes, includes methods for treating and inhibiting HIV-1 replication, particularly in HIV-1 infected cells.
(FR)La présente invention concerne des composés chélateurs destinés à chélater des ions métalliques. En particulier, la présente invention concerne des composés de (thio)semicarbazone et des composés de (thio)hydrazone, tels que PpYeT et PpYaT, qui sont des chélateurs d'ions métalliques, y compris les ions de fer. L'utilisation thérapeutique de tels composés et/ou de leurs complexes d'ions métalliques, comprend des procédés de traitement et d'inhibition de la réplication du VIH-1, en particulier dans des cellules infectées par le VIH-1.
Estados designados: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Língua de publicação: English (EN)
Língua de depósito: English (EN)