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1. (WO2004094608) HUMAN PROCOLIPASE LIKE NUCLEIC ACIDS AND POLYPEPTIDES AND THEIR METHODS OF USE THREOF
Dados bibliográficos mais recentes no arquivo da Secretaria Internacional   

№ de pub.:    WO/2004/094608    № do pedido internacional:    PCT/US2004/012290
Data de publicação: 04.11.2004 Data de depósito internacional: 19.04.2004
Pedido de exame (capítulo 2) depositado:    07.10.2004    
CIP:
A61K 38/17 (2006.01), C12P 21/02 (2006.01), C12Q 1/68 (2006.01)
Requerentes: CURAGEN CORPORATION [US/US]; 555 Long Wharf Drive, New Haven, CT 06511 (US) (For All Designated States Except US).
DI-HALVORSEN, Yuan [US/US]; (US) (For US Only).
ARJONA, Anibal, A. [US/US]; (US) (For US Only).
PATTURAJAN, Meera [IN/US]; (US) (For US Only).
MILLER, Charles, E. [US/US]; (US) (For US Only)
Inventores: DI-HALVORSEN, Yuan; (US).
ARJONA, Anibal, A.; (US).
PATTURAJAN, Meera; (US).
MILLER, Charles, E.; (US)
Mandatário: YAHWAK, George; C/O CuraGen Corporation, 555 Long Wharf Drive, New Haven, CT 06511 (US)
Dados da prioridade:
60/463,822 18.04.2003 US
60/323,519 19.09.2001 US (IA Considered Withdrawn 26.07.2004)
10/236,392 06.09.2002 US (IA Considered Withdrawn 26.07.2004)
Título (EN) HUMAN PROCOLIPASE LIKE NUCLEIC ACIDS AND POLYPEPTIDES AND THEIR METHODS OF USE THREOF
(FR) ACIDES NUCLEIQUES ET POLYPEPTIDES APPARENTES A LA PROCOLIPASE HUMAINE ET LEURS METHODES D'UTILISATION
Resumo: front page image
(EN)This invention relates to novel procolipase-like polynucleotides, polypeptides and antibodies. The invention also describes the related procolipase variants. Disclosed herein are the use of the novel procolipase-like polynucleotides, polypeptides and antibodies and their variants in the methods of treating overweight, obesity, dislipidemia and cardiovascular diseases. Also described herein are the uses of the polypeptide as a therapeutic with a combined effect of lipase inhibition and appetite suppression.
(FR)Cette invention concerne de nouveaux polynucléotides, polypeptides et anticorps apparentés à la procolipase, ainsi que les variants voisins de la procolipase. L'invention concerne également l'utilisation des nouveaux polynucléotides, polypeptides et anticorps apparentés à la procolipase ainsi que de leurs variants dans les méthodes de traitement de la surcharge pondérale, de l'obésité, de la dyslipidémie et des maladies cardiovasculaires. L'invention concerne en outre les utilisations du polypeptide comme agent thérapeutique présentant une action combinée d'inhibition de la lipase et de diminution de l'appétit.
Estados designados: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Língua de publicação: English (EN)
Língua de depósito: English (EN)