WIPO - 국제 및 국내 특허문헌 검색

1.WO/2022/140845NEUTRALIZING MONOCLONAL ANTIBODIES AGAINST COVID-19

WO - 07.07.2022

국제특허분류 C07K 16/10 출원번호 PCT/CA2021/051873 출원인 VAL-CHUM, LIMITED PARTNERSHIP 발명자 STAMATATOS, Leonidas

2.WO/2022/228827HUMAN NEUTRALIZING MONOCLONAL ANTIBODIES AGAINST SARS-COV-2 AND USES THEREOF

WO - 03.11.2022

국제특허분류 C07K 16/10 출원번호 PCT/EP2022/058777 출원인 INSTITUT PASTEUR 발명자 MOUQUET, Hugo

The invention relates to antibodies against Severe Acute Respiratory Syndrome-related Coronavirus 2 (SARS-CoV-2), in particular human neutralizing monoclonal antibodies against Severe Acute Respiratory Syndrome-related Coronavirus 2 (SARS-CoV-2) and their use for the diagnosis, monitoring, prevention, and treatment of SARS-CoV-2 infection and associated disease (COVID-19).

3.20210353620Method of treating severe acute respiratory syndrome (SARS) virus infection by administering a protein disulfide isomerase (PDI) inhibitor

US - 18.11.2021

국제특허분류 A61K 31/496 출원번호 17320069 출원인 The University of Vermont and State Agricultural College 발명자 Vikas Anathy

Compositions and methods involving protein disulfide isomerase (PDI) inhibitors, such as protein disulfide isomerase A3 (PDIA3) inhibitory compounds, for human coronavirus, such as severe acute respiratory syndrome (SARS) virus (e.g., SARS-CoV-2), therapies are disclosed herein.

4.WO/2022/165039ANTI-SARS-COV-2 SPIKE GLYCOPROTEIN ANTIBODIES AND THE THERAPEUTIC USE THEREOF

WO - 04.08.2022

국제특허분류 C07K 16/10 출원번호 PCT/US2022/014103 출원인 TALEM THERAPEUTICS LLC 발명자 ROODINK, Ilse

The present application relates to neutralizing antibodies or antigen-binding fragments thereof against betacoronaviruses such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), to nucleic acid(s) encoding such neutralizing antibodies or antigen-binding fragments thereof, and to mixture and compositions comprising such antibodies, antigen-binding fragments or nucleic acids. Such neutralizing antibodies or antigen-binding fragments thereof are able to block betacoronavirus entry into cells and/or to induce complement-dependent cytotoxicity (CDC), antibody-dependent cellular cytotoxicity (ADCC) and/or antibody-dependent cellular phagocytosis (ADCP) against betacoronavirus-infected cells. Methods and uses of the antibodies, antigen-binding fragments thereof, nucleic acid(s) or compositions, including therapeutic, diagnostic, and preventative methods and uses for betacoronavirus infections and related diseases such as COVID-19, are also described.

5.WO/2006/086561NEUTRALIZING MONOCLONAL ANTIBODIES AGAINST SEVERE ACUTE RESPIRATORY SYNDROME-ASSOCIATED CORONAVIRUS

WO - 17.08.2006

국제특허분류 A61K 39/00 출원번호 PCT/US2006/004599 출원인 NEW YORK BLOOD CENTER 발명자 JIANG, Shibo

The present invention provides an isolated antibody capable of binding to the receptor- binding domain of the spike protein of the severe acute respiratory syndrome-associated coronavirus (SARS-CoV) so as to competitively inhibit the binding of the SARS-CoV to host cells. These mAbs or substances can be used: 1) as passive-immunizing agents for prevention of SARS-CoV infection; 2) as biological reagents for diagnosis of SARS-CoV infection; 3) as immunotherapeutics for early treatment of SARS-CoV infection; and 4) as probes for studying the immunogenicity, antigenicity, structure, and function of the SARS- CoV S protein.

6.WO/2005/018535COMPOSITIONS AND METHODS FOR TREATMENT OF SEVERE ACUTE RESPIRATORY SYNDROME (SARS)

WO - 03.03.2005

국제특허분류 A61K 39/395 출원번호 PCT/US2004/015864 출원인 WYETH HOLDINGS CORPORATION 발명자 SIBER, George, R.

Compositions and methods for treating Severe Acute Respiratory Syndrome (SARS) are disclosed herein. Inhibitors of SARS-associated inflammatory cytokines are provided herein for use in treating SARS, including SARS-associated coronavirus (SARS-CoV) infection. Inhibitors of TNF are disclosed herein, as is the use of said inhibitors for treating SARS, including SARS-CoV. Methods of identifying and screening for said inhibitors are also provided.

7.WO/2022/216223VACCINE AND/OR ANTIBODY FOR VIRAL INFECTION

WO - 13.10.2022

국제특허분류 C07K 16/10 출원번호 PCT/SG2021/050497 출원인 INTRA-IMMUSG PRIVATE LIMITED (SG) 발명자 ZENG, Qi

The present invention relates to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) N-protein and/or an immunogenic fragment thereof and uses thereof. The invention includes an antibody capable of binding to the SARS-CoV-2 N-protein or antigen-binding fragment thereof and uses thereof

8.WO/2021/186190CORONAVIRUS ANTIBODY

WO - 23.09.2021

국제특허분류 C07K 16/10 출원번호 PCT/GB2021/050685 출원인 IMPERIAL COLLEGE INNOVATIONS LIMITED 발명자 XU, Xiao-Ning

An antibody or antigen-binding fragment thereof is described which binds to the spike protein S2 domain of severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome-related coronavirus (MERS-CoV) and/ or severe acute respiratory syndrome coronavirus 2 (SARS CoV-2). The antibodies can be used in the diagnosis and treatment of coronavirus infection. The invention extends to compositions comprising the antibodies, including pharmaceutical compositions, diagnostic compositions, and kits. The invention also extends to methods of making and using the antibodies, for example in the diagnosis and therapy of coronavirus infections.

9.20230127518IDEBENONE FOR THE TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) IN PATIENTS DIAGNOSED WITH A CORONAVIRUS INFECTION

US - 27.04.2023

국제특허분류 A61K 31/122 출원번호 17911781 출원인 BEMIDO SA 발명자 Giampiero DE LUCA

The present invention relates to idebenone for treating Acute Respiratory Distress Syndrome (ARDS) associated with a viral infection, particularly a coronavirus infection, such as Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

10.3101131COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING CORONAVIRUS INFECTION - SARSCOV-2 VACCINES

CA - 31.07.2021

국제특허분류 C12N 15/15 출원번호 3101131 출원인 JANSSEN PHARMACEUTICALS, INC. 발명자 LANGEDIJK, JOHANNES PETRUS MARIA

P217625CA00 CR U6043CAN P1- 269 -COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING CORONAVIRUS INFECTION - SARS-COV-2 VACCINESAbstractThe invention relates to immunogenic compositions and vaccines containing a coronavirus(e.g., Wuhan coronavirus (2019-nCoV; also referred to as SARS-CoV-2)) protein or a polynucleotide encoding a coronavirus (e.g., Wuhan coronavirus (2019-nCoV; SARS-CoV-2)) protein and uses thereof. The invention also provides methods of treating and/or preventing a coronavirus (e.g., Wuhan coronavirus (2019-nCoV; SARS-CoV-2)) infectionby administering an immunogenic composition or vaccine to a subject (e.g., a human). Theinvention also provides methods of detecting and/or monitoring a protective anti-coronavirus (e.g., Wuhan coronavirus (2019-nCoV; SARS-CoV-2)) antibody response (e.g., anti-coronavirus antibody response, e.g., anti-2019-nCoV antibody response, e.g., anti-Spike antibody response, e.g., anti-Spike neutralizing antibody response). The presentinvention relates to isolated nucleic and/or recombinant nucleic acid encoding acoronavirus S protein, in particular a SARS-CoV-2 S protein, and to the coronavirus S proteins, as well as to the use of the nucleic acids and/or proteins thereof in vaccines.<1093966>Date Recue/Date Received 2020-11-28

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