WIPO - 국제 및 국내 특허문헌 검색

1.20080044814Oligonucleotides, reagents and amplification methods for detecting severe acute respiratory syndrome coronavirus

US - 21.02.2008

국제특허분류 C12Q 1/70 출원번호 10552327 출원인 Genome Institute of Singapore 발명자 Ren Ee Chee

This invention provides oligonucleotides, reagents and amplification methods for detecting the severe acute respiratory syndrome coronavirus (SARS CoV). This invention also provides related compositions, kits, systems, and computers.

2.20050142536Method and kit for the detection of a novel coronoavirus associated with the severe acute respiratory syndrome (SARS)

US - 30.06.2005

국제특허분류 C12Q 1/68 출원번호 10837026 출원인 QIAGEN Diagnostics GmbH 발명자 Laue Thomas

The instant invention relates to a quantitative real time RT-PCR method for detecting Severe Acute Respiratory Syndrome-associated virus (SARS-associated virus) and to oligonucleotides and kits for detecting SARS-associated virus.

3.WO/2005/042767COMPOSITIONS AND METHODS FOR DETECTING SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS

WO - 12.05.2005

국제특허분류 C12P 19/34 출원번호 PCT/US2004/036689 출원인 DIAGNOSTIC HYBRIDS, INC. 발명자 SCHOLL, David, R.

The invention provides compositions and methods for detecting the presence of SARS-coronavirus, for screening anti-SARS coronavirus agents and vaccines, and for reducing infection with plus-strand RNA viruses such as SARS-coronavirus.

4.20050037338Method and means for detection of severe acute respiratory syndrome

US - 17.02.2005

국제특허분류 C12P 19/34 출원번호 10640032 출원인 발명자 Tseng Kuo-Tang

A diagnostic means and method of detecting the presence or the absence of severe acute respiratory syndrome coronavirus antibody in a test sample. The means comprises a solid support, an unlabeled recombinant antigen peptide on a first area of the solid support, a labeled recombinant antigen peptide on a second area of the solid support and an internal control antibody peptide on a third area of the solid phase. The first area is located between the second and the third area.

5.20060263847Compositions and methods for treatment of severe acute respiratory syndrome (SARS)

US - 23.11.2006

국제특허분류 A61K 39/215 출원번호 10557479 출원인 Wyeth 발명자 Siber George R.

Compositions and methods for treating Severe Acute Respiratory Syndrome (SARS) are disclosed herein. Inhibitors of SARS-associated inflammatory cytokines are provided herein for use in treating SARS, including SARS-associated coronavirus (SARS-CoV) infection. Inhibitors of TNF are disclosed herein, as is the use of said inhibitors for treating SARS, including SARS-CoV. Methods of identifying and screening for said inhibitors are also provided.

6.20070099178Method for detecting SARS coronavirus

US - 03.05.2007

국제특허분류 C12Q 1/68 출원번호 10561947 출원인 Eiken Kagaku Kabushiki Kaisha 발명자 Minekawa Harumi

This invention provides: a method for detecting SARS pathogenic viruses with high sensitivity and rapidity for diagnosing severe acute respiratory syndrome (SARS); an oligonucleotide primer that can specifically hybridize with any nucleotide sequence constructed based on the nucleotide sequence of RNA polymerase of the SARS coronavirus; a method for nucleic acid amplification using such primer; a method for diagnosing infection with the SARS coronavirus via detection of nucleic acid amplification; and a kit for diagnosing SARS.

7.20220401550Nucleic acid vaccine against the SARS-CoV-2 coronavirus

US - 22.12.2022

국제특허분류 A61K 39/215 출원번호 17819187 출원인 INSTITUT PASTEUR 발명자 Etienne Simon-Loriere

The invention relates to an immunogenic or vaccine composition against the 2019 novel coronavirus (SARS-CoV-2), comprising a nucleic acid construct encoding a SARS-CoV-2 coronavirus Spike (S) protein antigen or a fragment thereof comprising the receptor-binding domain, wherein the nucleic acid construct sequence is codon-optimized for expression in human.

8.20090226885Nucleic acid sequences that can be used as primers and probes in the amplification and detection of SARS coronavirus

US - 10.09.2009

국제특허분류 C07H 21/04 출원번호 10559949 출원인 Biomerieux, B.V. 발명자 Sillekens Peter T. G.

The present invention is related to nucleic acid sequences that can be used in the field of virus diagnostics, more specifically the diagnosis of infections with a novel human coronavirus causing Severe Acute Respiratory Syndrome (SARS). With the present invention nucleotide sequences are provided that can be used as primers and probes in the amplification and detection of SARS nucleic acid. The oligonucleotide sequences provided with the present invention are located in the replicase gene, the nucleocapsid gene and the 3′ end non-coding region of the SARS Coronavirus genome. It has been found that, by using the sequences of the present invention in methods for the amplification and detection of nucleic acid a sensitive and specific detection of SARS Coronavirus can be obtained. The oligonucleotide sequences according to the present invention are especially useful in methods for the amplification of nucleic acid.

9.20040229211Sensitive diagnostic testing methodology using multiplex real time PCR with one dye (MOD) and its use as in severe acute respiratory syndrome (SARS)

US - 18.11.2004

국제특허분류 C12P 19/34 출원번호 10455043 출원인 발명자 Yeung Wah Hin Alex

This invention provides a new and more sensitive methodology for multiplex real time PCR testing of any genetic materials. The method is best illustrated here with the detection and diagnosis of Severe Acute Respiratory Syndrome (SARS) but can be applicable to any other usage where more sensitivity is required. It can be combined with the usual multiplex real time PCR test for further confirmation and multiple parameter assessment of SARS or other diseases. A kit form is provided for the detection of SARS by this methodology, but equally applicable to other diseases or testing conditions.

10.WO/2021/183899METHODS AND KITS FOR THE DETECTION OF SARS-COV-2

WO - 16.09.2021

국제특허분류 C12P 19/34 출원번호 PCT/US2021/022128 출원인 THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE 발명자 ENGELTHALER, David

Methods, kits, and oligonucleotides used in the detection of coronavirus, for example, SARS-CoV-2, CoV-HKU1, CoV-OC43, CoV-229E, and CoV-NL63, are disclosed. A method of detecting coronavirus may include contacting a sample with at least one primer pair and probe targeting SARS-CoV-2 and at least one of: a primer pair and probe targeting CoV-HKU1, a primer pair and probe targeting CoV-OC43, a primer pair and probe targeting CoV-229E, a primer pair and probe targeting CoV-NL63, subjecting the mixture to conditions that allow nucleic acid amplification, and detecting the presence or absence of coronavirus, including SARS-CoV-2, CoV-HKU1, CoV-OC43, CoV-229E, and/or CoV-NL63, by analyzing the nucleic acid amplification products.

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