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1. (WO2019025857) ADDITIVELY MANUFACTURED FUNCTIONAL DOSAGE FORMS
국제사무국에 기록된 최신 서지정보    정보 제출

공개번호: WO/2019/025857 국제출원번호: PCT/IB2018/000974
공개일: 07.02.2019 국제출원일: 30.07.2018
IPC:
A61K 9/48 (2006.01) ,B29C 64/118 (2017.01) ,B29C 64/336 (2017.01)
A SECTION A — 생활필수품 농업
61
위생학; 의학 또는 수의학
K
의약용, 치과용 또는 화장용 제제
9
특별한 물리적 형태에 의하여 특징 지어지는 의약품 제제
48
캡슐제제, 예. 젤라틴제, 초콜렛제
[IPC code unknown for B29C 64/118][IPC code unknown for B29C 64/336]
출원인:
TEVA PHARMACEUTICALS INDUSTRIES LIMITED [IL/IL]; 5 Basel Street 49131 Petach Tikva, IL
발명자:
NIE, Haichen; US
DRAGER, Anthony; US
WATTAMWAR, Paritosh; US
MCINTYRE, Bradley; US
YAZDANIAN SR., Mehan; US
대리인:
KORAKH, Eliav; IL
우선권 정보:
62/539,30331.07.2017US
발명의 명칭: (EN) ADDITIVELY MANUFACTURED FUNCTIONAL DOSAGE FORMS
(FR) FORMES GALÉNIQUES FONCTIONNELLES FABRIQUÉES DE MANIÈRE ADDITIVE
요약서:
(EN) 3D printed functional dosage forms, and methods for making thereof are disclosed. In one aspect of the disclosure, a dosage form is presented that includes an outer shell printed from a first material and at least one inner core containing an active pharmaceutical ingredient (API) disposed within the outer shell. The dosage form includes an opening structure extending from an outer surface of the outer shell to the at least one inner core. The dosage form may include a plurality of pH sensitive mucoadhesive projections printed from a third material and extending from the outer shell. The dosage form may include a plug printed from the second or third material within the opening structure and can include an outer cap printed over the plug from a fourth material. The dosage form also may include an internal hollow cavity such that the dosage form is buoyant in an aqueous solution.
(FR) L'invention concerne des formes galéniques fonctionnelles imprimées en 3D, et des procédés de fabrication correspondants. Selon un aspect de l'invention, une forme galénique comprend une écorce externe imprimée à partir d'un premier matériau et au moins un cœur interne contenant un principe actif pharmaceutique (API) disposé à l'intérieur de l'écorce externe. La forme galénique comprend une structure d'ouverture s'étendant d'une surface externe de l'écorce externe au dit cœur interne. La forme galénique peut comprendre une pluralité de saillies mucoadhésives sensibles au pH imprimées à partir d'un troisième matériau et s'étendant à partir de l'écorce externe. La forme galénique peut comprendre un bouchon imprimé à partir du deuxième ou du troisième matériau à l'intérieur de la structure d'ouverture et peut comprendre un capuchon externe imprimé sur le bouchon à partir d'un quatrième matériau. La forme galénique peut également comprendre une cavité creuse interne de telle sorte que la forme galénique est flottante dans une solution aqueuse.
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지정국: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
아프리카지역 지식재산권기구(ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
유라시아 특허청 (AM, AZ, BY, KG, KZ, RU, TJ, TM)
유럽 특허청(EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
공개언어: 영어 (EN)
출원언어: 영어 (EN)