WO2018202202 COMPOUND WITH KINASE INHIBITORY ACTIVITY AND PREPARATION METHOD AND USE THEREOF

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1. (WO2018202202) COMPOUND WITH KINASE INHIBITORY ACTIVITY AND PREPARATION METHOD AND USE THEREOF

국제사무국에 기록된 최신 서지정보

공개번호:	WO/2018/202202	국제출원번호:	PCT/CN2018/085848
공개일:	08.11.2018	국제출원일:	07.05.2018

IPC:

C07D 401/14 (2006.01) ,C07D 403/14 (2006.01) ,C07D 405/14 (2006.01) ,A61K 31/506 (2006.01) ,A61K 31/5377 (2006.01) ,A61K 31/501 (2006.01) ,A61P 35/00 (2006.01)

출원인:

上海时莱生物技术有限公司 SELECTION BIOSCIENCE LLC [CN/CN]; 中国上海市自由贸易区蔡伦路230号1幢4层 4th Floor, Building 1, No.230 Cailun Road, Shanghai Free Trade Zone Shanghai 201203, CN

발명자:

张富尧 ZHANG, Fuyao; CN

陈先杰 CHEN, Xianjie; CN

方为军 FANG, Weijun; CN

孙华 SUN, Hua; CN

대리인:

上海弼兴律师事务所 SHANGHAI BESHINING LAW OFFICE; 中国上海市小木桥路681号外经大厦21楼 21st Floor SFECO Mansion 681 Xiaomuqiao Road Shanghai 200032, CN

우선권 정보:

201710315240.4

05.05.2017

발명의 명칭:

(EN) COMPOUND WITH KINASE INHIBITORY ACTIVITY AND PREPARATION METHOD AND USE THEREOF
(FR) COMPOSÉ PRÉSENTANT UNE ACTIVITÉ INHIBITRICE DE KINASE, SON PROCÉDÉ DE PRÉPARATION ET SON UTILISATION
(ZH) 具有激酶抑制活性的化合物、其制备方法和用途

요약서:

(EN) The present invention provides a compound as shown in general formulas (I) or (II) and a pharmaceutically acceptable salt, an isomer or a mixture form thereof, a solvate, a polymorph, a stable isotope derivative, or a prodrug of the same. The compound of the present invention has CDK kinase inhibitory activity and can be used in treating a disease related to CDK kinase, such as a cancer.
(FR) La présente invention concerne un composé tel que représenté dans les formules générales (I) ou (II) et un sel pharmaceutiquement acceptable, un isomère ou une forme de mélange de celui-ci, un solvate, un polymorphe, un dérivé isotopique stable, ou un promédicament de celui-ci. Le composé de la présente invention a une activité inhibitrice de la kinase CDK et peut être utilisé dans le traitement d'une maladie associée à une kinase CDK, telle qu'un cancer.
(ZH) 本发明公开了一种如通式(I)或(II)所示的化合物、其药学上可接受的盐、异构体或其混合物形式、溶剂化物、多晶型物、稳定的同位素衍生物或前药。本发明的化合物具有CDK激酶抑制活性，可用于治疗CDK激酶相关的疾病，如癌症等。

지정국:

AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
아프리카지역 지식재산권기구(ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
유라시아 특허청 (AM, AZ, BY, KG, KZ, RU, TJ, TM)
유럽 특허청(EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)

공개언어:

중국어 (ZH)

출원언어:

중국어 (ZH)

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