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1. (WO2017214379) SIMULATING LIVING CELL IN SILICO
국제사무국에 기록된 최신 서지정보    정보 제출

공개번호: WO/2017/214379 국제출원번호: PCT/US2017/036526
공개일: 14.12.2017 국제출원일: 08.06.2017
IPC:
C12M 1/36 (2006.01) ,C12M 1/34 (2006.01)
C SECTION C — 화학; 야금
12
생화학; 맥주; 주정; 포도주; 식초; 미생물학; 효소학; 돌연변이 또는 유전자공학
M
효소학 또는 미생물학을 위한 장치
1
효소학 또는 미생물학을 위한 장치
36
조건 또는 시간에 따라 조절되는 것을 포함하는 것, 예. 자동조절된 발효기
C SECTION C — 화학; 야금
12
생화학; 맥주; 주정; 포도주; 식초; 미생물학; 효소학; 돌연변이 또는 유전자공학
M
효소학 또는 미생물학을 위한 장치
1
효소학 또는 미생물학을 위한 장치
34
상태의 측정 또는 검출수단으로 측정 또는 시험을 행하는 것, 예. 콜로니 계수기
출원인:
X DEVELOPMENT LLC [US/US]; 1600 Amphitheatre Parkway Mountain View, CA 94043, US
발명자:
THOUPPAURACHCHI, Chirath; US
PEIKON, Ian; US
THOMPSON, Jason; US
SPALINK, Tammo; US
대리인:
RELLINGER, Benjamin, Addison; US
우선권 정보:
15/177,04708.06.2016US
발명의 명칭: (EN) SIMULATING LIVING CELL IN SILICO
(FR) SIMULATION DE CELLULE VIVANTE IN SILICO
요약서:
(EN) The behavior and/or internal activities of a microorganism can be simulated using a model of the microorganism. Such simulations can be used to determine the efficacy of treatments, disinfectants, antibiotics, chemotherapies, or other methods of interacting with the microorganism, or to provide some other information about the microorganism. Systems and methods are provided herein for fitting, refining, or otherwise improving such models in an automated fashion. Such systems and methods include performing whole-cell experiments to determine a correspondence between the predictions of such models and the actual behavior of samples of the microorganism. Such systems and methods also include, based on such determined correspondences, directly assessing determined discrete sets of properties of the microorganism and/or of constituents of the microorganism and updating parameters of the model corresponding to the properties of the discrete set such that the overall accuracy of the model is improved.
(FR) La présente invention décrit le comportement et/ou les activités internes d’un micro-organisme pouvant être simulés à l'aide d'un modèle du micro-organisme. De telles simulations peuvent être utilisées en vue de déterminer l’efficacité des traitements, des désinfectants, des antibiotiques, des chimiothérapies, ou d’autres procédés d’interaction avec le micro-organisme, ou en vue de fournir certaines autres informations sur le micro-organisme. Les systèmes et les procédés sont décrits ici pour l’ajustement, l’affinage, ou sinon l’amélioration de tels modèles d’une manière automatisée. De tels systèmes et procédés comprennent l’exécution d’expérimentations sur des cellules entières en vue de déterminer une correspondance entre les prédictions de tels modèles et le comportement réel des échantillons du micro-organisme. De tels systèmes et procédés comprennent également, sur la base de telles correspondances déterminées, l’évaluation directement déterminée d’ensembles discrets de propriétés du micro-organisme et/ou des constituants du micro-organisme et la mise à jour des paramètres du modèle correspondant aux propriétés de l’ensemble discret de sorte que la précision globale du modèle soit améliorée.
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지정국: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
아프리카지역 지식재산권기구(ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
유라시아 특허청 (AM, AZ, BY, KG, KZ, RU, TJ, TM)
유럽 특허청(EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
공개언어: 영어 (EN)
출원언어: 영어 (EN)