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1. (WO2017214010) TEMPORAL MULTIPLEXED EXCITATION FOR MINIATURIZED, PLANAR FLUORESCENCE ACTIVATED CELL SORTING
국제사무국에 기록된 최신 서지정보    정보 제출

공개번호: WO/2017/214010 국제출원번호: PCT/US2017/035887
공개일: 14.12.2017 국제출원일: 05.06.2017
IPC:
G01N 15/14 (2006.01) ,B01L 3/00 (2006.01)
G SECTION G — 물리학
01
측정; 시험
N
재료의 화학적 또는 물리적 성질의 검출에 의한 재료의 조사 또는 분석
15
입자의 특징의 조사; 다공성 재료의 투과율, 기공량 또는 표면적의 조사
10
개별의 입자조사
14
전기광학적 조사
B SECTION B — 처리조작; 운수
01
물리적 방법, 화학적 방법 또는 장치일반
L
일반적으로 사용되는 화학 또는 물리 실험장치
3
실험용 용기 또는 접시, 예. 실험용글라스기구; 점적기
출원인:
VERILY LIFE SCIENCES LLC [US/US]; 1600 Amphitheatre Parkway Mountain View, CA 94043, US
발명자:
SINHA, Supriyo; US
RABKIN, Brian; US
대리인:
MACHONKIN, Richard, A.; US
우선권 정보:
62/346,20606.06.2016US
발명의 명칭: (EN) TEMPORAL MULTIPLEXED EXCITATION FOR MINIATURIZED, PLANAR FLUORESCENCE ACTIVATED CELL SORTING
(FR) EXCITATION MULTIPLEXÉE DANS LE TEMPS POUR TRI CELLULAIRE ACTIVÉ PAR FLUORESCENCE PLANAIRE, MINIATURISÉ
요약서:
(EN) A system for fluorescence activated cell sorting includes at least two excitation lasers and an objective that directs light from the at least two excitation lasers to a common point in an interrogation region of a fluidic channel. The fluidic channel directs a flow of a plurality of fluorescently labeled particles through the interrogation region. At least one modulator temporally multiplexes light from the at least two excitation lasers such that pulses of light from different lasers intersect the common point at different times. The system further includes at least one detector and at least one optical element that directs light emitted from the particles and transmitted through the objective to the at least one detector. The system may further include optics for generating and detecting side and forward scattered light. Methods for operating example systems to collect fluorescent, side scattered and forward scattered light are also described herein.
(FR) Cette invention concerne un système de tri cellulaire activé par fluorescence comprenant au moins deux lasers d'excitation et un objectif qui dirige la lumière provenant desdits deux lasers d'excitation vers un point commun dans une région d'interrogation d'un canal fluidique. Le canal fluidique dirige un flux constitué d'une pluralité de particules marquées par fluorescence dans la région d'interrogation. Au moins un modulateur multiplexe la lumière provenant desdits deux lasers d'excitation dans le temps de façon que les impulsions lumineuses provenant des différents lasers coupent le point commun à des temps différents. Le système comprend en outre au moins un détecteur et au moins un élément optique qui dirige la lumière émise par les particules et transmise à travers l'objectif audit détecteur. Le système peut en outre comprendre une optique pour générer et détecter la lumière diffusée latérale et vers l'avant. Des procédés de fonctionnement de systèmes illustratifs pour collecter la lumière fluorescente, diffusée latéralement et diffusée vers l'avant sont en outre décrits.
front page image
지정국: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
아프리카지역 지식재산권기구(ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
유라시아 특허청 (AM, AZ, BY, KG, KZ, RU, TJ, TM)
유럽 특허청(EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
공개언어: 영어 (EN)
출원언어: 영어 (EN)