국제 및 국내 특허문헌 검색

1. (WO2015157704) METHODS AND COMPOSITIONS FOR DETECTING MISFOLDED PROTEINS

Pub. No.:    WO/2015/157704    International Application No.:    PCT/US2015/025432
Publication Date: Fri Oct 16 01:59:59 CEST 2015 International Filing Date: Sat Apr 11 01:59:59 CEST 2015
IPC: G01N 33/52
G01N 33/68
Applicants: YALE UNIVERSITY
Inventors: BUHIMSCHI, Irina
BUHIMSCHI, Catalin, S.
CHOMA, Michael
TAGARE, Hemant
JONAS, Stephan, Michael
Title: METHODS AND COMPOSITIONS FOR DETECTING MISFOLDED PROTEINS
Abstract:
Various aspects and embodiments of the present disclosure are directed to methods and compositions (e.g., kits) for the identification of subjects with misfolded proteins in their urine. For example, methods and compositions for determining that a urine sample from a pregnant woman contains or does not contain misfolded are provided. In some embodiments, the presence of misfolded proteins in a urine sample from a pregnant woman is an indication of preeclampsia.