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1. (WO2004094986) SYSTEM AND METHOD FOR ELECTROCHEMICAL DETECTION OF BIOLOGICAL COMPOUNDS
국제사무국에 기록된 최신 서지정보

공개번호: WO/2004/094986 국제출원번호: PCT/US2004/011900
공개일: 04.11.2004 국제출원일: 16.04.2004
IPC:
C12Q 1/68 (2006.01)
C SECTION C — 화학; 야금
12
생화학; 맥주; 주정; 포도주; 식초; 미생물학; 효소학; 돌연변이 또는 유전자공학
Q
효소 또는 미생물을 함유한 측정 또는 시험방법; 그것을 위한 조성물 또는 시험지; 그 조성물을 조제하는 방법; 미생물학적 또는 효소학적 방법에 있어서의 상태응답 제어
1
효소 또는 미생물을 함유한 측정 또는 시험방법; 그것을 위한 조성물; 그 조성물의 제조방법
68
핵산을 함유한 것
출원인:
HANDYLAB, INC. [US/US]; 5230 S. State Road Suite 100 Ann Arbor, MI 48108-9754, US (AllExceptUS)
ALTHAUS, John, S. [US/US]; US (UsOnly)
KYONGHOON, Lee [KR/US]; US (UsOnly)
NAMASIVAYAM, Vijay [IN/US]; US (UsOnly)
BRAHMASANDRA, Sundaresh, N. [IN/US]; US (UsOnly)
HANDIQUE, Kalyan [IN/US]; US (UsOnly)
발명자:
ALTHAUS, John, S.; US
KYONGHOON, Lee; US
NAMASIVAYAM, Vijay; US
BRAHMASANDRA, Sundaresh, N.; US
HANDIQUE, Kalyan; US
대리인:
FISTER, Julius, C., III; Fish & Richardson P.C. 1425 K Street, NW Washington, DC 20005, US
우선권 정보:
60/463,04716.04.2003US
발명의 명칭: (EN) SYSTEM AND METHOD FOR ELECTROCHEMICAL DETECTION OF BIOLOGICAL COMPOUNDS
(FR) SYSTEME ET PROCEDE DE DETECTION ELECTROCHIMIQUE DE COMPOSES BIOLOGIQUES
요약서:
(EN) The present invention relates to an electrochemical method for detecting a target polynucleotide. An electrode comprising an electrode surface is provided. The electrode surface includes at least one probe molecule reverisbly immobilized with respect to the electrode surface. A first electrochemical signal indicative of an amount of probe molecule immobilized with respect to the electrode surface is obtained. The electrode surface is contacted with a liquid comprising the target polynucleotide. Upon the contacting step, at least some of the probe molecule immobilized with respect to the electrode surface dissociates therefrom. A second electrochemical signal indicative of an amount of probe molecule immobilized with respect to the electrode surface is obtained. The presence of the target polynucleotide is determined at least partially on the basis of the first and second electrochemical signals.
(FR) La présente invention concerne un procédé électrochimique de détection d'un polynucléotide cible. Une électrode comprenant une surface d'électrode est prévue. La surface d'électrode comprend au moins une molécule sonde immobilisée de manière réversible par rapport à la surface d'électrode. Un premier signal électrochimique indiquant une quantité de molécule sonde immobilisée par rapport à la surface d'électrode est obtenu. La surface d'électrode est mise en contact avec un liquide comprenant le polynucléotide cible. Lors de l'étape de mise en contact, au moins une partie de la molécule sonde immobilisée par rapport à la surface d'électrode se dissocie de celle-ci. Un second signal électrochimique indiquant une quantité de molécule sonde immobilisée par rapport à la surface d'électrode est obtenu. La présence du polynucléotide cible est déterminée au moins partiellement sur la base des premier et second signaux électrochimiques.
front page image
지정국: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
아프리카지역 지식재산권기구(ARIPO) (BW, GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
유라시아 특허청(EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
유럽 특허청(EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
아프리카 지식재산권기구(OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
공개언어: 영어 (EN)
출원언어: 영어 (EN)
또한로 출판 됨:
US20060207891